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Entry version 7 (31 Jul 2019)
Sequence version 1 (27 Sep 2017)
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Protein

WD_REPEATS_REGION domain-containing protein

Gene

Celaphus_00004260

Organism
Cervus elaphus hippelaphus (European red deer)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WD_REPEATS_REGION domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:Celaphus_00004260Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCervus elaphus hippelaphus (European red deer)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri46360 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraCervidaeCervinaeCervus

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini275 – 316WD_REPEATS_REGIONInterPro annotationAdd BLAST42
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati275 – 308WDPROSITE-ProRule annotationAdd BLAST34

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 24DisorderedSequence analysisAdd BLAST24
Regioni552 – 587DisorderedSequence analysisAdd BLAST36
Regioni651 – 713DisorderedSequence analysisAdd BLAST63
Regioni728 – 752DisorderedSequence analysisAdd BLAST25
Regioni788 – 861DisorderedSequence analysisAdd BLAST74
Regioni902 – 956DisorderedSequence analysisAdd BLAST55
Regioni1526 – 1549DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi673 – 688PolarSequence analysisAdd BLAST16
Compositional biasi733 – 752PolarSequence analysisAdd BLAST20
Compositional biasi821 – 835PolarSequence analysisAdd BLAST15
Compositional biasi841 – 857PolarSequence analysisAdd BLAST17

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032401 EDC4_WD40
IPR026144 Neuritin_fam
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16529 Ge1_WD40, 1 hit
PF15056 NRN1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320 WD40, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978 SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50082 WD_REPEATS_2, 1 hit
PS50294 WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

A0A212DE32-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
SSEWPFLPLG PSAENQRPSN AYNGDLNGLL VPDPLCSGDS ASTNKPGLRA
60 70 80 90 100
MPPINLQEKQ VICLLGDDSS TGIGILAKEV EIVASSDSSI SSKARGSNKV
110 120 130 140 150
KIQPVAKYDW EQKYYYGNLI AVSNSFLAYA IRAANNGSAM VRVISVSTSE
160 170 180 190 200
RTLLKGFTGS VADLAFAHLN SPQLACLDEA GNLFVWRLAL INGKIQEEIL
210 220 230 240 250
VHIRQPEGTP LNHFRRIIWC PFIPEESEDC CEEGSPTVAL LHEDRAEVWD
260 270 280 290 300
LDMLRTNHST WPVDVTQIKQ GFIVVKGHST CLSEGALSPD GTVLATASHD
310 320 330 340 350
GFVKFWQIYI EGQDEPRCLH EWKPHDGRPL SCLLFCDNHK KQDPEVPFWR
360 370 380 390 400
FLITGADQNR ELKMWCTVSW TCLQTIRFSP DIFSPVSVPP SLKVCLDLSA
410 420 430 440 450
EYLILSDVQR KVGCSGGRAG SIGGMKVCVA HLGPSYTLNS AVTLPPMQVL
460 470 480 490 500
YVMELLQNQE EGRACFSSIS EFLLTHPVLS FGIQVVSRCR LRHTEVLPAE
510 520 530 540 550
EENDSLGADG THGAGAMESA AGVLIKLFCV HTKALQDVQI RFQPQLNPDV
560 570 580 590 600
VAPLPSHPAH EDFAFGESRP ELGSEGLGSA TQGSQPDLRR IVELPAPADF
610 620 630 640 650
LSLSSETKPK LMTPDAFMTP SASLQQIAAS PSSSSSSSSS SLTAVSAMSS
660 670 680 690 700
TSVVDPSLPR PPEELTLSPK LQLDGGLTMS SSSLQASPRG LLPGLLPGPA
710 720 730 740 750
DKLTPKGPGQ VPTAASALAL ELQEVEPLGL PQASPSRTRS PDVISSASTA
760 770 780 790 800
LSQDIPEIAS EALSRGFGAS APEGLEPDSM ASAASALHLL SPRPRPGPEL
810 820 830 840 850
GPQLSLDGSP GDGDRHSTPS LLEAALTQEA TAPDSQVWPT APDITRETCS
860 870 880 890 900
SLAESPRNGL QEKHKSLAFH RPPYHLLQQH DSQDASAEQS DHDDEVASLA
910 920 930 940 950
SAAGNFGTKV PTPRLPAKDW KTKGSPRASP KLKRKGKKDD GDSSLGSRLT
960 970 980 990 1000
EHQVAETPEN WPALIWQQQR ELAQLRHSQE ELLQRLCTQL EGLQSTVTGH
1010 1020 1030 1040 1050
VERALDDSTE RRLERALAEG QQRGGQLQEQ LTQQLSQALS SAVAGRLERS
1060 1070 1080 1090 1100
IRDEIKKTVP PCVSRSLEPV AGQLSNSVAT KLTAVESSMK ENISKLLKSK
1110 1120 1130 1140 1150
NLTDAIARAA ADTLQGPMQA AYREAFQSVV LPAFEKSCQA MFQQINDSFR
1160 1170 1180 1190 1200
LGTQEYLQQL ESHMKSRKAR EQEAREPVLA QLRGLVSTLQ GATEQMAATV
1210 1220 1230 1240 1250
SGSVRAEVQH QLHVAVGSLQ EAILAQVQRI VKGEVSVALK EQQAAVTSSI
1260 1270 1280 1290 1300
MQAMRSAAGT PVPAAHLDCQ AQQAHILQLL QQGHLNQAFQ QALTAADLNL
1310 1320 1330 1340 1350
VLYVCETVDP GQVFGQPPCP LSQPVLLSLI QQLASDLGTR TDLKLSYLEE
1360 1370 1380 1390 1400
AVMHLDHSDP ITRDHMGSVM AQVRQKLFQF LQAEPHNSLG KAARRSQLGM
1410 1420 1430 1440 1450
MRCCCCCCCH HRQPPCALGL LLLLLLPPLV PVSPLAAATA GPGRCDTIYH
1460 1470 1480 1490 1500
GFAECLIRLG DGMGHGGELE TVCRSWNDFH TCASRVLSGC PEEAAAVWES
1510 1520 1530 1540
LQQEARRAPH PDNLHTLCGT PVRLQERGVG PETNQETLRA TAPAPTPAP
Length:1,549
Mass (Da):167,130
Last modified:September 27, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3DF31915B8EA08ED
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei1549Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
MKHE01000004 Genomic DNA Translation: OWK16480.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MKHE01000004 Genomic DNA Translation: OWK16480.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR032401 EDC4_WD40
IPR026144 Neuritin_fam
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF16529 Ge1_WD40, 1 hit
PF15056 NRN1, 1 hit
SMARTiView protein in SMART
SM00320 WD40, 3 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50082 WD_REPEATS_2, 1 hit
PS50294 WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A212DE32_CEREH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A212DE32
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 27, 2017
Last sequence update: September 27, 2017
Last modified: July 31, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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