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Protein

Ribonuclease 3

Gene

rnc

Organism
Shewanella sp. FDAARGOS_354
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi42MagnesiumUniRule annotation1
Active sitei46UniRule annotation1
Metal bindingi115MagnesiumUniRule annotation1
Active sitei118UniRule annotation1
Metal bindingi118MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-binding, rRNA-bindingUniRule annotationSAAS annotation
Biological processmRNA processingUniRule annotationSAAS annotation, rRNA processingUniRule annotationSAAS annotation, tRNA processingUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease 3UniRule annotation (EC:3.1.26.3UniRule annotation)
Alternative name(s):
Ribonuclease IIIUniRule annotation
Short name:
RNase IIIUniRule annotation
Gene namesi
Name:rncUniRule annotation
ORF Names:CEQ32_09225Imported
OrganismiShewanella sp. FDAARGOS_354Imported
Taxonomic identifieri1930557 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000197056 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 129RNase IIIInterPro annotationAdd BLAST123
Domaini156 – 226DRBMInterPro annotationAdd BLAST71

Sequence similaritiesi

Belongs to the ribonuclease III family.SAAS annotation

Phylogenomic databases

KOiK03685

Family and domain databases

CDDicd00048 DSRM, 1 hit
cd00593 RIBOc, 1 hit
Gene3Di1.10.1520.10, 1 hit
HAMAPiMF_00104 RNase_III, 1 hit
InterProiView protein in InterPro
IPR014720 dsRBD_dom
IPR011907 RNase_III
IPR000999 RNase_III_dom
IPR036389 RNase_III_sf
PfamiView protein in Pfam
PF00035 dsrm, 1 hit
PF14622 Ribonucleas_3_3, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 1 hit
SM00535 RIBOc, 1 hit
SUPFAMiSSF69065 SSF69065, 1 hit
TIGRFAMsiTIGR02191 RNaseIII, 1 hit
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 1 hit
PS00517 RNASE_3_1, 1 hit
PS50142 RNASE_3_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1Z4AB70-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPIKNLPRL CRTLGYEFKN IDLLTQALTH RSAANKHNER LEFLGDSILS
60 70 80 90 100
IVISDALYHQ FPKATEGDLS RMRATLVRGD TLTLIAQAFK LGDYLFLGPG
110 120 130 140 150
ELKSGGFRRE SILADAVEAI IGAIYLDSDL EVCRELLLKW YAERLAEIQP
160 170 180 190 200
GVNQKDAKTL LQEYLQGLKK PLPDYQVINI EGDAHDQTFT VECRIDDLSE
210 220
SVIGVASSRR KAEQIAAAQV LELLKK
Length:226
Mass (Da):25,299
Last modified:November 22, 2017 - v1
Checksum:i1DC00D629CE0BBD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP022089 Genomic DNA Translation: ASF15148.1

Genome annotation databases

KEGGishf:CEQ32_09225

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP022089 Genomic DNA Translation: ASF15148.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGishf:CEQ32_09225

Phylogenomic databases

KOiK03685

Family and domain databases

CDDicd00048 DSRM, 1 hit
cd00593 RIBOc, 1 hit
Gene3Di1.10.1520.10, 1 hit
HAMAPiMF_00104 RNase_III, 1 hit
InterProiView protein in InterPro
IPR014720 dsRBD_dom
IPR011907 RNase_III
IPR000999 RNase_III_dom
IPR036389 RNase_III_sf
PfamiView protein in Pfam
PF00035 dsrm, 1 hit
PF14622 Ribonucleas_3_3, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 1 hit
SM00535 RIBOc, 1 hit
SUPFAMiSSF69065 SSF69065, 1 hit
TIGRFAMsiTIGR02191 RNaseIII, 1 hit
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 1 hit
PS00517 RNASE_3_1, 1 hit
PS50142 RNASE_3_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1Z4AB70_9GAMM
AccessioniPrimary (citable) accession number: A0A1Z4AB70
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: September 12, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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