Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Forkhead box protein O6

Gene

FOXO6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi88 – 182Fork-headPROSITE-ProRule annotationAdd BLAST95

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscriptionSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box protein O6Imported
Gene namesi
Name:FOXO6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A1X9RU27

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 182Fork-headInterPro annotationAdd BLAST95

Phylogenomic databases

KOiK17847

Family and domain databases

CDDicd00059 FH, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR032067 FOXO-TAD
IPR032068 FOXO_KIX-bd
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
PF16676 FOXO-TAD, 1 hit
PF16675 FOXO_KIX_bdg, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1X9RU27-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAKLRAHQV DVDPDFAPQS RPRSCTWPLP QPDLAGDEDG ALGAGVAEGA
60 70 80 90 100
EDCGPERRAT APAMAPAPPL GAEVGPLRKA KSSRRNAWGN LSYADLITKA
110 120 130 140 150
IESAPDKRLT LSQIYDWMVR YVPYFKDKGD SNSSAGWKNS IRHNLSLHTR
160 170 180 190 200
FIRVQNEGTG KSSWWMLNPE GGKTGKTPRR RAVSMDNGAK FLRIKGKASK
210 220 230 240 250
KKQLQAPERS PDDSSPSAPA PGPVPAAAKW AASPASHASD DYEAWADFRG
260 270 280 290 300
GGRPLLGEAA ELEDDEALEA LAPSSPLMYP SPASALSPAL GSRCPGELPR
310 320 330 340 350
LAELGGPLGL HGGGGAGLPE GLLDGAQDAY GPRARAGTPA YFGGCKGGAY
360 370 380 390 400
GGGGGFGPPA MGALRRLPMQ TIQENKQASF VPAAAPFRPG ALPALLPPPP
410 420 430 440 450
PAPRPGPVLG APGELALAGA AAAYPGKGAA PYAPPAPSRS ALAHPISLMT
460 470 480 490 500
LPGEAGAAGL APSGHAAAFG GPPGGLLLDA LPGPYAAAAA GPLGAAPDRF
510 520 530 540 550
PADLDLDMFS GSLECDVESI ILNDFMDSDE MDFNFDSALP PPPPGLAGAP

PPNQSWVPG
Length:559
Mass (Da):57,202
Last modified:August 30, 2017 - v1
Checksum:iFA7CD2463739405B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KY243080 mRNA Translation: ARQ84049.1
RefSeqiNP_001278210.2, NM_001291281.2
UniGeneiHs.559677

Genome annotation databases

GeneIDi100132074
KEGGihsa:100132074

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KY243080 mRNA Translation: ARQ84049.1
RefSeqiNP_001278210.2, NM_001291281.2
UniGeneiHs.559677

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A1X9RU27

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100132074
KEGGihsa:100132074

Organism-specific databases

CTDi100132074

Phylogenomic databases

KOiK17847

Miscellaneous databases

ChiTaRSiFOXO6 human

Family and domain databases

CDDicd00059 FH, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR032067 FOXO-TAD
IPR032068 FOXO_KIX-bd
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
PF16676 FOXO-TAD, 1 hit
PF16675 FOXO_KIX_bdg, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1X9RU27_HUMAN
AccessioniPrimary (citable) accession number: A0A1X9RU27
Entry historyiIntegrated into UniProtKB/TrEMBL: August 30, 2017
Last sequence update: August 30, 2017
Last modified: November 7, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again