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Protein
Submitted name:

EPCAM

Gene

EPCAM

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
EPCAMImported
Gene namesi
Name:EPCAMImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei266 – 289HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501098414723 – 314Sequence analysisAdd BLAST292

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

ExpressionAtlasiA0A1X9RRB4 baseline and differential

Structurei

3D structure databases

SMRiA0A1X9RRB4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 135Thyroglobulin type-1InterPro annotationAdd BLAST73

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

KOiK06737
OMAiREKPYDV

Family and domain databases

CDDicd00191 TY, 1 hit
Gene3Di4.10.800.10, 1 hit
InterProiView protein in InterPro
IPR000716 Thyroglobulin_1
IPR036857 Thyroglobulin_1_sf
PfamiView protein in Pfam
PF00086 Thyroglobulin_1, 1 hit
SMARTiView protein in SMART
SM00211 TY, 1 hit
SUPFAMiSSF57610 SSF57610, 1 hit
PROSITEiView protein in PROSITE
PS00484 THYROGLOBULIN_1_1, 1 hit
PS51162 THYROGLOBULIN_1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A0A1X9RRB4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPPQVLAFG LLLAAATAAV AAAQQGCVCE NYKLTTNCSL NALGQCQCTS
60 70 80 90 100
IGAQNSVICS KLASKCLVMK AEMTGSKAGR RLKPENAIQN NDGLYDPDCD
110 120 130 140 150
ENGLFKAKQC NGTSMCWCVN TAGVRRTDKD SEISCLERVR TYWIIIELKH
160 170 180 190 200
KTREKPYDVT SLQNALKEVI TDRYQLDPKY ITNILYENDI ITIDLVQNSS
210 220 230 240 250
QKTLNEVDIA DVAYYFEKDV KDESLFHSKR MDLRVNGELL DLDPGQTSIY
260 270 280 290 300
YVDEKPPEFS MQGLQAGIIA VIAVVAIAIV AGIIVLIVST KKRRAKYEKA
310
EIKEMGEMHR ELNA
Length:314
Mass (Da):34,833
Last modified:August 30, 2017 - v1
Checksum:i88177EFD6D20D1F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KX904866 mRNA Translation: ARQ82883.1
RefSeqiNP_999584.1, NM_214419.1
UniGeneiSsc.51858

Genome annotation databases

GeneIDi403163
KEGGissc:403163

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KX904866 mRNA Translation: ARQ82883.1
RefSeqiNP_999584.1, NM_214419.1
UniGeneiSsc.51858

3D structure databases

SMRiA0A1X9RRB4
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi403163
KEGGissc:403163

Organism-specific databases

CTDi4072

Phylogenomic databases

KOiK06737
OMAiREKPYDV

Gene expression databases

ExpressionAtlasiA0A1X9RRB4 baseline and differential

Family and domain databases

CDDicd00191 TY, 1 hit
Gene3Di4.10.800.10, 1 hit
InterProiView protein in InterPro
IPR000716 Thyroglobulin_1
IPR036857 Thyroglobulin_1_sf
PfamiView protein in Pfam
PF00086 Thyroglobulin_1, 1 hit
SMARTiView protein in SMART
SM00211 TY, 1 hit
SUPFAMiSSF57610 SSF57610, 1 hit
PROSITEiView protein in PROSITE
PS00484 THYROGLOBULIN_1_1, 1 hit
PS51162 THYROGLOBULIN_1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1X9RRB4_PIG
AccessioniPrimary (citable) accession number: A0A1X9RRB4
Entry historyiIntegrated into UniProtKB/TrEMBL: August 30, 2017
Last sequence update: August 30, 2017
Last modified: October 10, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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