Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 15 (12 Aug 2020)
Sequence version 1 (05 Jul 2017)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

100633604

Organism
Amphimedon queenslandica (Sponge)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:100633604Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAmphimedon queenslandica (Sponge)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri400682 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaPoriferaDemospongiaeHeteroscleromorphaHaploscleridaNiphatidaeAmphimedon
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007879 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini199 – 213CCHC-typeInterPro annotationAdd BLAST15
Domaini449 – 650Reverse transcriptaseInterPro annotationAdd BLAST202
Domaini778 – 931Integrase catalyticInterPro annotationAdd BLAST154

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni239 – 261DisorderedSequence analysisAdd BLAST23
Regioni1014 – 1105DisorderedSequence analysisAdd BLAST92

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili99 – 119Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1014 – 1075PolyampholyteSequence analysisAdd BLAST62

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0017, Eukaryota

Database of Orthologous Groups

More...
OrthoDBi
583605at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.70.10, 1 hit
3.30.420.10, 1 hit
3.30.70.270, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR021109, Peptidase_aspartic_dom_sf
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR000477, RT_dom
IPR001878, Znf_CCHC
IPR036875, Znf_CCHC_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17921, Integrase_H2C2, 1 hit
PF00665, rve, 1 hit
PF00078, RVT_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00343, ZnF_C2HC, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50630, SSF50630, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
SSF57756, SSF57756, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50994, INTEGRASE, 1 hit
PS50878, RT_POL, 1 hit
PS50158, ZF_CCHC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1X7TR37-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAENTPYGRL EEFSPEIETF ASYSERVELF LQAHAVPDDR QVAVVLNAVG
60 70 80 90 100
VKNYSLLRGL VAPAKPSEKT VTELLDLLKG HYEPEPVIIA ERYHFYTRNQ
110 120 130 140 150
KEEESVAQYA AELRRLASTC SFGDHLDDAL RDRLVCGILS AGARKKLLAE
160 170 180 190 200
KKLKFQGAVA IATNYETIEK DSRSIQQQHE SGDAHKVAYK GKDTGDKPCY
210 220 230 240 250
RCGRQGHAPS TCRFRNARCN NCSKLGHIAA VCRSNQGKKY NRSQGKTHKV
260 270 280 290 300
DEQADETSGE SEDDLGVFQI QSISSHSPPI MISLKLNGQT IEMELDTGAS
310 320 330 340 350
VSLISEEVKD KYLPHVPLQP THIRLQTYTA QSIKVLGKCQ VTVKYGVQEK
360 370 380 390 400
SLVVIVVAGK RPCLFGRNWL KHIVLDWSSI SHVSLAEKQK VDKVCSKYGA
410 420 430 440 450
VFREETGIMK NFKAKLQLKK DAIPRFHRPR QVPFALKEAV GQELDRLEGC
460 470 480 490 500
GILEKVKTSE WAAPIVAVPK KDGRIRVCGD YKVTINPFLD IDVYPLPNVD
510 520 530 540 550
EMFAVMAGGE KFTKLDLTNA YQQMELDNLS RDLVTINTHQ GLYRYTRLPF
560 570 580 590 600
GVASAPAVFQ RTMDTILQGL DKVVCYIDDI LLTGVDDNDH LKTLEAVLQR
610 620 630 640 650
LQQHGITLKK GYRSTEQHGN ADSLSRLPLP HCPKRELDVD TLFNIIHMSS
660 670 680 690 700
LPLTHSKLKA ATLTDPKLSK IMGFIRTGWP QTVDEELAAY WRRRNELSVE
710 720 730 740 750
IGCLLWGRRV IIPRKLQKQV LLELHTGHPG ICRMKSLARS HLWWPNLDAD
760 770 780 790 800
IEQLARSCRP CLEVKSTMTP PPLHPWIWPR KPWTRVHLDF AGPLYGKMYL
810 820 830 840 850
LAVDACSKWP EVWEMSSTTA KRTVQILSHL FGLYGLPEQI VTDNGPQFVS
860 870 880 890 900
EEFCSFLRER GVKHFRSAPY HPATNGAVER FVKTFKQALK IGRQEGKLSS
910 920 930 940 950
QEVIDRFLLQ YRSTPHATTL STPAELFLGR LLRTRLDLMK PEIYQEVERQ
960 970 980 990 1000
QAHQKHYFDR RGCDRVFTLG QNVLVREYCR GGVKWSFGQI TGICGPLSYW
1010 1020 1030 1040 1050
IKLEDGRQVR RHVEQLKKGS ARDRVDKDIN DDWMSHTTEP QIEESPDLRD
1060 1070 1080 1090 1100
ETGYHGNEDQ GSEGMAEDQL ERQEVDTPSE TTSPVPRYPR RNRRVPERPF

MVSLS
Length:1,105
Mass (Da):125,547
Last modified:July 5, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i08931C9BC5268D16
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_019858296.1, XM_020002737.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
Aqu2.1.17263_001; Aqu2.1.17263_001; Aqu2.1.17263

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100633604

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
aqu:100633604

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_019858296.1, XM_020002737.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiAqu2.1.17263_001; Aqu2.1.17263_001; Aqu2.1.17263
GeneIDi100633604
KEGGiaqu:100633604

Phylogenomic databases

eggNOGiKOG0017, Eukaryota
OrthoDBi583605at2759

Family and domain databases

Gene3Di2.40.70.10, 1 hit
3.30.420.10, 1 hit
3.30.70.270, 1 hit
InterProiView protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR021109, Peptidase_aspartic_dom_sf
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR000477, RT_dom
IPR001878, Znf_CCHC
IPR036875, Znf_CCHC_sf
PfamiView protein in Pfam
PF17921, Integrase_H2C2, 1 hit
PF00665, rve, 1 hit
PF00078, RVT_1, 1 hit
SMARTiView protein in SMART
SM00343, ZnF_C2HC, 2 hits
SUPFAMiSSF50630, SSF50630, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
SSF57756, SSF57756, 1 hit
PROSITEiView protein in PROSITE
PS50994, INTEGRASE, 1 hit
PS50878, RT_POL, 1 hit
PS50158, ZF_CCHC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1X7TR37_AMPQE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1X7TR37
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2017
Last sequence update: July 5, 2017
Last modified: August 12, 2020
This is version 15 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again