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Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Mycolicibacterium doricum
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei68Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processDNA damage, DNA repairUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
Short name:
UDGUniRule annotation
Gene namesi
Name:ungUniRule annotation
ORF Names:AWC01_05745Imported
OrganismiMycolicibacterium doricumImported
Taxonomic identifieri126673 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycolicibacterium
Proteomesi
  • UP000193564 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 214UDGInterPro annotationAdd BLAST162

Sequence similaritiesi

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd10027 UDG_F1, 1 hit
Gene3Di3.40.470.10, 1 hit
HAMAPiMF_00148 UDG, 1 hit
InterProiView protein in InterPro
IPR002043 UDG_fam1
IPR018085 Ura-DNA_Glyclase_AS
IPR005122 Uracil-DNA_glycosylase-like
IPR036895 Uracil-DNA_glycosylase-like_sf
PANTHERiPTHR11264 PTHR11264, 1 hit
PfamiView protein in Pfam
PF03167 UDG, 1 hit
SMARTiView protein in SMART
SM00986 UDG, 1 hit
SUPFAMiSSF52141 SSF52141, 1 hit
TIGRFAMsiTIGR00628 ung, 1 hit
PROSITEiView protein in PROSITE
PS00130 U_DNA_GLYCOSYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1X1TFT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTARALSELV DQGWAQALEP VHEQVAQVGE FLRAELAAGH RYLPAGANVL
60 70 80 90 100
RAFSFPFDRV RVLLVGQDPY PTPGHAVGLS FSVDPQVRPL PRSLANIFTE
110 120 130 140 150
YTADLGHPQP NNGDLTPWAK RGVLLLNRVL TVRPGAPASH RGKGWEAVTE
160 170 180 190 200
CAIRALVARD TPMVALLWGR DAATLKPMLT GNGCVAIESP HPSPLSASRG
210 220
FFGSRPFSRA NELLTEMGAE PIDWQLP
Length:227
Mass (Da):24,582
Last modified:July 5, 2017 - v1
Checksum:iAA3FF3A09EC3DAB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LQOS01000018 Genomic DNA Translation: ORV43424.1

Similar proteinsi

Entry informationi

Entry nameiA0A1X1TFT4_9MYCO
AccessioniPrimary (citable) accession number: A0A1X1TFT4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2017
Last sequence update: July 5, 2017
Last modified: July 18, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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