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Entry version 12 (17 Jun 2020)
Sequence version 1 (05 Jul 2017)
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Protein
Submitted name:

Secretion protein EccB

Gene

AWC00_28180

Organism
Mycobacterium conspicuum
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi499 – 506ATPPROSITE-ProRule annotation8
Nucleotide bindingi876 – 883ATPPROSITE-ProRule annotation8
Nucleotide bindingi1178 – 1185ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
GCF_002102095:AWC00_RS28440-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Secretion protein EccBImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:AWC00_28180Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium conspicuumImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44010 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000193407 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei37 – 59HelicalSequence analysisAdd BLAST23
Transmembranei71 – 90HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini476 – 678FtsKInterPro annotationAdd BLAST203
Domaini858 – 1052FtsKInterPro annotationAdd BLAST195
Domaini1161 – 1354FtsKInterPro annotationAdd BLAST194

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR023836 EccCa-like_Actinobacteria
IPR023837 EccCb-like_Actinobacteria
IPR002543 FtsK_dom
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01580 FtsK_SpoIIIE, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03924 T7SS_EccC_a, 1 hit
TIGR03925 T7SS_EccC_b, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50901 FTSK, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1X1SSK6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRGFARPTP EKPPVIKPEN IVLPTPLSIP PPEGKPWWLI VVGVLVIGLL
60 70 80 90 100
GGMVAMVFAS GSHVFGGAGS IFPIFMVGGM MMMMFGGRFG GQQQMSRPKL
110 120 130 140 150
DAMRAQFMLM LDMLRETANE SADSMDANYR WYHPAPNTLA AAVGSSRMWE
160 170 180 190 200
RKPDGKDLNF GVVRVGVGMT RPEVTWGEPQ NMPTDIELEP VTGKALQEFG
210 220 230 240 250
RYQSVVYNLP KMVSVMVEPW YSLLGEREQV LGLMRSIICQ LAFSHGPDHV
260 270 280 290 300
RMIVVTSDLE EWDWVKWLPH FGDPRRQDAA GSARMVYGSV REFAAEQAEL
310 320 330 340 350
FAGRGSFTPR HASSAAQTPT PHHVIIADLT DPQWEYVISS EGVDGVTFFD
360 370 380 390 400
LTGASMWSSV PERSLTFDKR GVIEALPRDR DTWMVIDDKP WFFALTDHLS
410 420 430 440 450
IPEAEEFAQK VARWRIAEAY EEIGQRVAHI GARDILSYYG IEDPADIDFD
460 470 480 490 500
ALWASRTDSM GRSRLRVPFG NRSDNGELLF LDMKSLDEGG DGPHGVMSGT
510 520 530 540 550
TGSGKSTLVR TVIESLMLGH PPEELQFVLA DLKGGSAVKP FAGVPHVSRI
560 570 580 590 600
ITDLEEDQAL MERFLDALWG EIARRKAVCD SAGVDDAKEY NSVRARMRAR
610 620 630 640 650
GQDMMPLPML VVVIDEFYEW FRIMPTAVDV LDSIGRQGRA YWIHLMMASQ
660 670 680 690 700
TIESRAEKLM ENMGYRLVLK ARTAGAAQAA GVPNAVNLPA QAGLGYFRKS
710 720 730 740 750
LEDIIRFQAE FLWRDYYARG VTVDGEEAPA LVHSIDYVRP QLFTNSFTPL
760 770 780 790 800
EVSVGGPEIE PILSNGSNGE AIEAEEVDDE DEGEGHIRTP KVGTVIIEQL
810 820 830 840 850
RKIDFEPYRL WQPPLTEPVA IDDLVDRFLG RPWNKDYGTA RDLVFPIGII
860 870 880 890 900
DRPFKHDQPP WTVDTSGAGS NVLILGAGGS GKTTALQTLI CAAALTHTPE
910 920 930 940 950
QVQFYCLAYS STALTTVARL PHVGEVVGPT DPYGVRRTVA EILALVRDRK
960 970 980 990 1000
RSFLEHGIAS MEMFRRRKFG GEAGPVPNDG FGDVYLVIDN YRALAEENEV
1010 1020 1030 1040 1050
LIEQVNVIIN QGPSFGVHVI ATADRESELR PPVRSGFGSR VELRLAAVED
1060 1070 1080 1090 1100
AKLVRSRFAK DVPVKPGRGM VAVNYVRLDA DPQSGLHTLV ARPALASTPN
1110 1120 1130 1140 1150
NTFESDSVVE AVSRVATSQA PPVRRLPAKF GVEQVRELAA RDTRQGVGVG
1160 1170 1180 1190 1200
GIVWAISELD LQPVYLNFAE NSHLVITGRR ECGRTTTLAT IMSEIGRLYA
1210 1220 1230 1240 1250
PGATSAPPPP AGRPSAQVWL IDPRRQLLTT LGSDYVEKFA YNLDGVVAMM
1260 1270 1280 1290 1300
GELAAALAGR EPPPGLSAEE LLSRSWWSGP EIFLIVDDIQ QLPPGFDSPL
1310 1320 1330 1340 1350
HKAVPWVTRA ADVGLHVIAT RTFGGWSSAG SDPMLRALHQ ANAPLLVMDA
1360 1370 1380 1390
DPDEGFIRGK MKGGPLPRGR GLLMAEDTGV FVQVAATELK R
Length:1,391
Mass (Da):152,928
Last modified:July 5, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFB7D2DB8034B8F86
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
LQOR01000084 Genomic DNA Translation: ORV33501.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LQOR01000084 Genomic DNA Translation: ORV33501.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Enzyme and pathway databases

BioCyciGCF_002102095:AWC00_RS28440-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR023836 EccCa-like_Actinobacteria
IPR023837 EccCb-like_Actinobacteria
IPR002543 FtsK_dom
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01580 FtsK_SpoIIIE, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 3 hits
SUPFAMiSSF52540 SSF52540, 2 hits
TIGRFAMsiTIGR03924 T7SS_EccC_a, 1 hit
TIGR03925 T7SS_EccC_b, 1 hit
PROSITEiView protein in PROSITE
PS50901 FTSK, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1X1SSK6_9MYCO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1X1SSK6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2017
Last sequence update: July 5, 2017
Last modified: June 17, 2020
This is version 12 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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