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Protein

Alpha-1,4 glucan phosphorylase

Gene

pygl

Organism
Scleropages formosus (Asian bonytongue)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.UniRule annotation

Catalytic activityi

((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase
Biological processCarbohydrate metabolismUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-1,4 glucan phosphorylaseUniRule annotation (EC:2.4.1.1UniRule annotation)
Gene namesi
Name:pyglImported
OrganismiScleropages formosus (Asian bonytongue)Imported
Taxonomic identifieri113540 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOsteoglossocephalaOsteoglossomorphaOsteoglossiformesOsteoglossidaeScleropages
Proteomesi
  • UP000192224 Componenti: Genome assembly

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei680N6-(pyridoxal phosphate)lysineUniRule annotation1

Family & Domainsi

Sequence similaritiesi

Belongs to the glycogen phosphorylase family.UniRule annotation

Phylogenomic databases

KOiK00688

Family and domain databases

CDDicd04300 GT1_Glycogen_Phosphorylase, 1 hit
InterProiView protein in InterPro
IPR011833 Glycg_phsphrylas
IPR000811 Glyco_trans_35
IPR035090 Pyridoxal_P_attach_site
PANTHERiPTHR11468 PTHR11468, 1 hit
PfamiView protein in Pfam
PF00343 Phosphorylase, 1 hit
PIRSFiPIRSF000460 Pprylas_GlgP, 1 hit
TIGRFAMsiTIGR02093 P_ylase, 1 hit
PROSITEiView protein in PROSITE
PS00102 PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1W4Y4C5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAPLSDHEK RKQISIRGIV GVENVSEIKK GFNRHLHFTL VKDRNIATHR
60 70 80 90 100
DYYFALAHTV RDHLVGRWIR TQQFYYETDP KRVYYLSLEF YMGRTLQNTM
110 120 130 140 150
INLGLQNACD EAIYQLGLDM EDLEEVEEDA GLGNGGLGRL AACFLDSMAT
160 170 180 190 200
LGLAAYGYGI RYEYGIFNQR IKEGWQVEEA DDWLRHGNPW EKARPEYMLP
210 220 230 240 250
VHFYGRVEET KKGPKWVDTQ VVLAMPYDTP VPGYMNNTVN TMRLWSARAP
260 270 280 290 300
NDFNLQDFNV GDYIQAVLDR NLAENISRVL YPNDHFFVGK ELRLKQEYFV
310 320 330 340 350
VAATLQDIIR RFKTSKREHT SSTISFDTFP DKVAIQLNDT HPALAIPELM
360 370 380 390 400
RILVDIEKLH WDKAWNITKR TFAYTNHTVL PEALERWPIQ LLETLLPRHL
410 420 430 440 450
QIIYEINQKH LDRIAALFPK DLDRLRRTSL IEEDGGKRIN MAHLCIVGSH
460 470 480 490 500
AVNGVAQIHS NIIKTDVFKD FSELEPDKFQ NKTNGITPRR WLLLCNPGLA
510 520 530 540 550
ELIAEAIGEE YVKDLSQLKK LNDFVDDDTF IRDISKVKQD NKEKFAQYLE
560 570 580 590 600
KVYKVKINPS SMFDVHVKRI HEYKRQLLNC LHIISMYNRI KKDPTAPFVP
610 620 630 640 650
RTVIIGGKAA PGYHMAKMII KLITSVAEVV NNDPVLDDKL KVIFLENYRV
660 670 680 690 700
SLAEKVIPAT DLSEQISLAG TEASGTGNMK FMLNGALTIG TMDGANVEMA
710 720 730 740 750
EEAGEDNLFI FGMRVEDVSE IDKKGYNAMK YYEQIPDLKQ VIDQIKSGFF
760 770 780 790 800
SPQQPALFKD ITEMLFKHDR FKVFADYEDY VCCQERVSRL YQKPKEWTKK
810 820 830 840 850
VIKNIAASGK FSSDRTITEY ATEIWGVEPT DLKIPSPNEP REAIEETARA

LKKASIL
Length:857
Mass (Da):98,604
Last modified:June 7, 2017 - v1
Checksum:i98DF4EE9E0913F1D
GO

Sequence databases

RefSeqiXP_018583260.1, XM_018727744.1

Genome annotation databases

GeneIDi108919616
KEGGisfm:108919616

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_018583260.1, XM_018727744.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi108919616
KEGGisfm:108919616

Organism-specific databases

CTDi5836

Phylogenomic databases

KOiK00688

Family and domain databases

CDDicd04300 GT1_Glycogen_Phosphorylase, 1 hit
InterProiView protein in InterPro
IPR011833 Glycg_phsphrylas
IPR000811 Glyco_trans_35
IPR035090 Pyridoxal_P_attach_site
PANTHERiPTHR11468 PTHR11468, 1 hit
PfamiView protein in Pfam
PF00343 Phosphorylase, 1 hit
PIRSFiPIRSF000460 Pprylas_GlgP, 1 hit
TIGRFAMsiTIGR02093 P_ylase, 1 hit
PROSITEiView protein in PROSITE
PS00102 PHOSPHORYLASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1W4Y4C5_9TELE
AccessioniPrimary (citable) accession number: A0A1W4Y4C5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: February 28, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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