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Protein
Submitted name:

Glial fibrillary acidic protein

Gene

Gfap

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Glial fibrillary acidic proteinImported
Gene namesi
Name:GfapImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi2679 Gfap

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Intermediate filamentPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 115IF rodInterPro annotationAdd BLAST115

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili13 – 86Sequence analysisAdd BLAST74

Sequence similaritiesi

Belongs to the intermediate filament family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00910000143989

Family and domain databases

InterProiView protein in InterPro
IPR027701 GFAP
IPR001664 IF
IPR018039 IF_conserved
IPR039008 IF_rod_dom
PANTHERiPTHR23239 PTHR23239, 1 hit
PTHR23239:SF41 PTHR23239:SF41, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

A0A1W2Q6C8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XLTDVASRNA ELLRQAKHEA NDYRRQLQAL TCDLESLRGT NESLERQMRE
60 70 80 90 100
QEERHARESA SYQEALARLE EEGQSLKEEM ARHLQEYQDL LNVKLALDIE
110 120 130 140 150
IATYRKLLEG EENRITIPVQ TFSNLQIRGG KSTKEGEGHK VTRHLKRLTI
160
QVIPIQALAR L
Length:161
Mass (Da):18,626
Last modified:June 7, 2017 - v1
Checksum:i081CD8AF39521EE8
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P47819GFAP_RAT
Glial fibrillary acidic protein
Gfap
430Annotation score:
A0A1W2Q658A0A1W2Q658_RAT
Glial fibrillary acidic protein
Gfap
51Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07072191 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000093266; ENSRNOP00000076226; ENSRNOG00000002919

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07072191 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000093266; ENSRNOP00000076226; ENSRNOG00000002919

Organism-specific databases

RGDi2679 Gfap

Phylogenomic databases

GeneTreeiENSGT00910000143989

Family and domain databases

InterProiView protein in InterPro
IPR027701 GFAP
IPR001664 IF
IPR018039 IF_conserved
IPR039008 IF_rod_dom
PANTHERiPTHR23239 PTHR23239, 1 hit
PTHR23239:SF41 PTHR23239:SF41, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1W2Q6C8_RAT
AccessioniPrimary (citable) accession number: A0A1W2Q6C8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: June 20, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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