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UniProtKB - A0A1W2PQL0 (A0A1W2PQL0_HUMAN)
Protein
Submitted name:
Heterogeneous nuclear ribonucleoprotein U
Gene
HNRNPU
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Heterogeneous nuclear ribonucleoprotein U |
Gene namesi | Name:HNRNPU |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:5048, HNRNPU |
VEuPathDBi | HostDB:ENSG00000153187 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 168 | B30.2/SPRYInterPro annotationAdd BLAST | 168 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 374 – 504 | DisorderedSequence analysisAdd BLAST | 131 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 374 – 391 | Basic and acidic residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 469 – 504 | Polar residuesSequence analysisAdd BLAST | 36 |
Phylogenomic databases
GeneTreei | ENSGT00940000156546 |
Family and domain databases
CDDi | cd12884, SPRY_hnRNP, 1 hit |
Gene3Di | 2.60.120.920, 1 hit 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR001870, B30.2/SPRY IPR043136, B30.2/SPRY_sf IPR013320, ConA-like_dom_sf IPR026745, hnRNP_U IPR027417, P-loop_NTPase IPR003877, SPRY_dom IPR035778, SPRY_hnRNP_U |
PANTHERi | PTHR12381:SF11, PTHR12381:SF11, 1 hit |
Pfami | View protein in Pfam PF00622, SPRY, 1 hit |
SMARTi | View protein in SMART SM00449, SPRY, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50188, B302_SPRY, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All
A0A1W2PQL0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XHFKISRDRL SASSLTMESF AFLWAGGRAS YGVSKGKVCF EMKVTEKIPV
60 70 80 90 100
RHLYTKDIDI HEVRIGWSLT TSGMLLGEEE FSYGYSLKGI KTCNCETEDY
110 120 130 140 150
GEKFDENDVI TCFANFESDE VELSYAKNGQ DLGVAFKISK EVLAGRPLFP
160 170 180 190 200
HVLCHNCAVE FNFGQKEKPY FPIPEEYTFI QNVPLEDRVR GPKGPEEKKD
210 220 230 240 250
CEVVMMIGLP GAGKTTWVTK HAAENPGKYN ILGTNTIMDK MMVAGFKKQM
260 270 280 290 300
ADTGKLNTLL QRAPQCLGKF IEIAARKKRN FILDQTNVSA AAQRRKMCLF
310 320 330 340 350
AGFQRKAVVV CPKDEDYKQR TQKKAEVEGK DLPEHAVLKM KGNFTLPEVA
360 370 380 390 400
ECFDEITYVE LQKEEAQKLL EQYKEESKKA LPPEKKQNTG SKKSNKNKSG
410 420 430 440 450
KNQFNRGGGH RGRGGFNMRG GNFRGGAPGN RGGYNRRGNM PQRGGGGGGS
460 470 480 490 500
GGIGYPYPRA PVFPGRGSYS NRGNYNRGGM PNRGNYNQNF RGRGNNRGYK
510 520
NQSQGYNQWQ QGSVHVNVLC GRVKGPN
Computationally mapped potential isoform sequencesi
There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ00839 | HNRPU_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU C1orf199, HNRPU, SAFA, U21.1 | 825 | Annotation score: | ||
A0A1W2PP22 | A0A1W2PP22_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 181 | Annotation score: | ||
Q5RI18 | Q5RI18_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 602 | Annotation score: | ||
A0A1W2PP34 | A0A1W2PP34_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 546 | Annotation score: | ||
A0A1W2PP35 | A0A1W2PP35_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 728 | Annotation score: | ||
A0A1W2PPH7 | A0A1W2PPH7_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 549 | Annotation score: | ||
A0A1W2PPL4 | A0A1W2PPL4_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 547 | Annotation score: | ||
A0A1X7SBS1 | A0A1X7SBS1_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 744 | Annotation score: | ||
A0A1W2PQD4 | A0A1W2PQD4_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 327 | Annotation score: | ||
A0A1W2PPS1 | A0A1W2PPS1_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 804 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX323046 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000638230.1; ENSP00000492010.1; ENSG00000153187.20 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX323046 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | A0A1W2PQL0 |
Genome annotation databases
Ensembli | ENST00000638230.1; ENSP00000492010.1; ENSG00000153187.20 |
Organism-specific databases
HGNCi | HGNC:5048, HNRNPU |
OpenTargetsi | ENSG00000153187 |
VEuPathDBi | HostDB:ENSG00000153187 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156546 |
Miscellaneous databases
ChiTaRSi | HNRNPU, human |
Gene expression databases
ExpressionAtlasi | A0A1W2PQL0, baseline and differential |
Family and domain databases
CDDi | cd12884, SPRY_hnRNP, 1 hit |
Gene3Di | 2.60.120.920, 1 hit 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR001870, B30.2/SPRY IPR043136, B30.2/SPRY_sf IPR013320, ConA-like_dom_sf IPR026745, hnRNP_U IPR027417, P-loop_NTPase IPR003877, SPRY_dom IPR035778, SPRY_hnRNP_U |
PANTHERi | PTHR12381:SF11, PTHR12381:SF11, 1 hit |
Pfami | View protein in Pfam PF00622, SPRY, 1 hit |
SMARTi | View protein in SMART SM00449, SPRY, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50188, B302_SPRY, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A1W2PQL0_HUMAN | |
Accessioni | A0A1W2PQL0Primary (citable) accession number: A0A1W2PQL0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 7, 2017 |
Last sequence update: | June 7, 2017 | |
Last modified: | May 25, 2022 | |
This is version 25 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |