The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - A0A1W2PPL4 (A0A1W2PPL4_HUMAN)
Protein
Submitted name:
Heterogeneous nuclear ribonucleoprotein U
Gene
HNRNPU
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Heterogeneous nuclear ribonucleoprotein U |
Gene namesi | Name:HNRNPU |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:5048, HNRNPU |
VEuPathDBi | HostDB:ENSG00000153187 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 186 | B30.2/SPRYInterPro annotationAdd BLAST | 186 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 393 – 471 | DisorderedSequence analysisAdd BLAST | 79 | |
Regioni | 491 – 521 | DisorderedSequence analysisAdd BLAST | 31 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 393 – 409 | Basic and acidic residuesSequence analysisAdd BLAST | 17 |
Phylogenomic databases
GeneTreei | ENSGT00940000156546 |
Family and domain databases
CDDi | cd12884, SPRY_hnRNP, 1 hit |
Gene3Di | 2.60.120.920, 1 hit 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR001870, B30.2/SPRY IPR043136, B30.2/SPRY_sf IPR013320, ConA-like_dom_sf IPR026745, hnRNP_U IPR027417, P-loop_NTPase IPR003877, SPRY_dom IPR035778, SPRY_hnRNP_U |
PANTHERi | PTHR12381:SF11, PTHR12381:SF11, 1 hit |
Pfami | View protein in Pfam PF00622, SPRY, 1 hit |
SMARTi | View protein in SMART SM00449, SPRY, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50188, B302_SPRY, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All
A0A1W2PPL4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFTLDVKSNT VFDIITDNCD LHFKISRDRL SASSLTMESF AFLWAGGRAS
60 70 80 90 100
YGVSKGKVCF EMKVTEKIPV RHLYTKDIDI HEVRIGWSLT TSGMLLEEFS
110 120 130 140 150
YGYSLKGIKT CNCETEDYGE KFDENDVITC FANFESDEVE LSYAKNGQDL
160 170 180 190 200
GVAFKISKEV LAGRPLFPHV LCHNCAVEFN FGQKEKPYFP IPEEYTFIQN
210 220 230 240 250
VPLEDRVRGP KGPEEKKDCE VVMMIGLPGA GKTTWVTKHA AENPGKYNIL
260 270 280 290 300
GTNTIMDKMM VAGFKKQMAD TGKLNTLLQR APQCLGKFIE IAARKKRNFI
310 320 330 340 350
LDQTNVSAAA QRRKMCLFAG FQRKAVVVCP KDEDYKQRTQ KKAEVEGKDL
360 370 380 390 400
PEHAVLKMKG NFTLPEVAEC FDEITYVELQ KEEAQKLLEQ YKEESKKALP
410 420 430 440 450
PEKKQNTGSK KSNKNKSGKN QFNRGGGHRG RGGFNMRGGN FRGGAPGNRG
460 470 480 490 500
GYNRRGNMPQ RGGGGGGSGG IGYPYPRAPV FPGRGSYSNR GNYNRGGMPN
510 520 530 540
RGNYNQNFRG RGNNRGYKNQ SQGYNQWQQG QFWGQKPWSQ HYHQGYY
Computationally mapped potential isoform sequencesi
There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ00839 | HNRPU_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU C1orf199, HNRPU, SAFA, U21.1 | 825 | Annotation score: | ||
A0A1W2PP22 | A0A1W2PP22_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 181 | Annotation score: | ||
Q5RI18 | Q5RI18_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 602 | Annotation score: | ||
A0A1W2PP34 | A0A1W2PP34_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 546 | Annotation score: | ||
A0A1W2PP35 | A0A1W2PP35_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 728 | Annotation score: | ||
A0A1W2PPH7 | A0A1W2PPH7_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 549 | Annotation score: | ||
A0A1X7SBS1 | A0A1X7SBS1_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 744 | Annotation score: | ||
A0A1W2PQD4 | A0A1W2PQD4_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 327 | Annotation score: | ||
A0A1W2PPS1 | A0A1W2PPS1_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 804 | Annotation score: | ||
A0A1W2PQ74 | A0A1W2PQ74_HUMAN | Heterogeneous nuclear ribonucleopro... | HNRNPU | 372 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX323046 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000638716.1; ENSP00000491601.1; ENSG00000153187.20 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX323046 Genomic DNA No translation available. |
3D structure databases
SMRi | A0A1W2PPL4 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | A0A1W2PPL4 |
Protocols and materials databases
Antibodypediai | 3158, 256 antibodies from 32 providers |
Genome annotation databases
Ensembli | ENST00000638716.1; ENSP00000491601.1; ENSG00000153187.20 |
Organism-specific databases
HGNCi | HGNC:5048, HNRNPU |
OpenTargetsi | ENSG00000153187 |
VEuPathDBi | HostDB:ENSG00000153187 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156546 |
Miscellaneous databases
ChiTaRSi | HNRNPU, human |
Gene expression databases
ExpressionAtlasi | A0A1W2PPL4, baseline and differential |
Family and domain databases
CDDi | cd12884, SPRY_hnRNP, 1 hit |
Gene3Di | 2.60.120.920, 1 hit 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR001870, B30.2/SPRY IPR043136, B30.2/SPRY_sf IPR013320, ConA-like_dom_sf IPR026745, hnRNP_U IPR027417, P-loop_NTPase IPR003877, SPRY_dom IPR035778, SPRY_hnRNP_U |
PANTHERi | PTHR12381:SF11, PTHR12381:SF11, 1 hit |
Pfami | View protein in Pfam PF00622, SPRY, 1 hit |
SMARTi | View protein in SMART SM00449, SPRY, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50188, B302_SPRY, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A1W2PPL4_HUMAN | |
Accessioni | A0A1W2PPL4Primary (citable) accession number: A0A1W2PPL4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 7, 2017 |
Last sequence update: | June 7, 2017 | |
Last modified: | May 25, 2022 | |
This is version 29 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |