UniProtKB - A0A1W2PPA3 (A0A1W2PPA3_HUMAN)
Protein
Glial fibrillary acidic protein
Gene
GFAP
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Glial fibrillary acidic proteinARBA annotation |
Gene namesi | Name:GFAPImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
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Organism-specific databases
HGNCi | HGNC:4235, GFAP |
Subcellular locationi
Cytoskeleton
- intermediate filament Source: UniProtKB-KW
- intermediate filament cytoskeleton Source: HPA
Keywords - Cellular componenti
Intermediate filamentARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 17 | IF rodInterPro annotationAdd BLAST | 17 |
Keywords - Domaini
Coiled coilARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000159539 |
Family and domain databases
InterProi | View protein in InterPro IPR027701, GFAP IPR018039, IF_conserved IPR039008, IF_rod_dom |
PANTHERi | PTHR45652:SF9, PTHR45652:SF9, 1 hit |
PROSITEi | View protein in PROSITE PS00226, IF_ROD_1, 1 hit PS51842, IF_ROD_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 21 potential isoforms that are computationally mapped.Show allAlign All
A0A1W2PPA3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XEIATYRKLL EGEENRITIP VQTFSNLQIR ETSLDTKSVS EGHLKRNIVV
60
KTVEMRDGEG THPETSGII
Computationally mapped potential isoform sequencesi
There are 21 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP14136 | GFAP_HUMAN | Glial fibrillary acidic protein | GFAP | 432 | Annotation score: | ||
A0A1W2PR46 | A0A1W2PR46_HUMAN | Glial fibrillary acidic protein | GFAP | 505 | Annotation score: | ||
A0A1W2PRT3 | A0A1W2PRT3_HUMAN | Glial fibrillary acidic protein | GFAP | 326 | Annotation score: | ||
K7EJU1 | K7EJU1_HUMAN | Glial fibrillary acidic protein | GFAP | 248 | Annotation score: | ||
A0A1X7SBR3 | A0A1X7SBR3_HUMAN | Glial fibrillary acidic protein | GFAP | 472 | Annotation score: | ||
A0A1X7SCE1 | A0A1X7SCE1_HUMAN | Glial fibrillary acidic protein | GFAP | 334 | Annotation score: | ||
K7EPI4 | K7EPI4_HUMAN | Glial fibrillary acidic protein | GFAP | 124 | Annotation score: | ||
K7EKH9 | K7EKH9_HUMAN | Glial fibrillary acidic protein | GFAP | 261 | Annotation score: | ||
A0A1W2PS58 | A0A1W2PS58_HUMAN | Glial fibrillary acidic protein | GFAP | 67 | Annotation score: | ||
B4DIR1 | B4DIR1_HUMAN | Glial fibrillary acidic protein | GFAP | 179 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC015936 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000638304; ENSP00000491042; ENSG00000131095 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC015936 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | A0A1W2PPA3 |
Protocols and materials databases
Antibodypediai | 3505, 2939 antibodies |
Genome annotation databases
Ensembli | ENST00000638304; ENSP00000491042; ENSG00000131095 |
Organism-specific databases
HGNCi | HGNC:4235, GFAP |
OpenTargetsi | ENSG00000131095 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159539 |
Miscellaneous databases
ChiTaRSi | GFAP, human |
Gene expression databases
ExpressionAtlasi | A0A1W2PPA3, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR027701, GFAP IPR018039, IF_conserved IPR039008, IF_rod_dom |
PANTHERi | PTHR45652:SF9, PTHR45652:SF9, 1 hit |
PROSITEi | View protein in PROSITE PS00226, IF_ROD_1, 1 hit PS51842, IF_ROD_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A1W2PPA3_HUMAN | |
Accessioni | A0A1W2PPA3Primary (citable) accession number: A0A1W2PPA3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 7, 2017 |
Last sequence update: | June 7, 2017 | |
Last modified: | April 7, 2021 | |
This is version 21 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |