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Protein

tRNA dimethylallyltransferase

Gene

miaA

Organism
Geobacillus sp. 46C-IIa
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i6A).UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Dimethylallyl diphosphate + adenine(37) in tRNA = diphosphate + N6-dimethylallyladenine(37) in tRNA.UniRule annotation

Cofactori

Mg2+UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 17ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported
Biological processtRNA processingUniRule annotation
LigandATP-bindingUniRule annotation, MagnesiumUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA dimethylallyltransferaseUniRule annotation (EC:2.5.1.75UniRule annotation)
Alternative name(s):
Dimethylallyl diphosphate:tRNA dimethylallyltransferaseUniRule annotation
Short name:
DMAPP:tRNA dimethylallyltransferaseUniRule annotation
Short name:
DMATaseUniRule annotation
Isopentenyl-diphosphate:tRNA isopentenyltransferaseUniRule annotation
Short name:
IPP transferaseUniRule annotation
Short name:
IPPTUniRule annotation
Short name:
IPTaseUniRule annotation
Gene namesi
Name:miaAUniRule annotation
ORF Names:B1690_01910Imported
OrganismiGeobacillus sp. 46C-IIaImported
Taxonomic identifieri1963025 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000192323 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Monomer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei101Interaction with substrate tRNAUniRule annotation1
Sitei124Interaction with substrate tRNAUniRule annotation1

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni12 – 17Substrate bindingUniRule annotation6
Regioni35 – 38Interaction with substrate tRNAUniRule annotation4

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili252 – 272Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the IPP transferase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

HAMAPiMF_00185 IPP_trans, 1 hit
InterProiView protein in InterPro
IPR018022 IPT
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01715 IPPT, 1 hit
SUPFAMiSSF52540 SSF52540, 4 hits
TIGRFAMsiTIGR00174 miaA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1V9BFF8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKVVVIVG PTAVGKTKLG IALAKKLGGE IISGDSMQIY KGMDIGTAKV
60 70 80 90 100
KPDEMEGVPH HLLDIKEPCE PFSVVEFQRL ARALIADISA RGRLPIIVGG
110 120 130 140 150
TGLYIQAAIY DYQFSDASSD EAYRRTLKQL AAEQGVEALH EQLEAVDPES
160 170 180 190 200
AARIHPHNIR RVIRALEVYH CTGKPFSEWQ RGQQRQLLYE TAIIGLTAER
210 220 230 240 250
NVLYRRINER VDEMIAEGLI EEARSLYDRG LRDCQAVQAI GYKELYDYFD
260 270 280 290 300
GRVSLDEAIE QLKQNSRRYA KRQLTWFRNQ MPVRWFDMTD PEPFAAKVEE
310
IFHYIAGKLR LEANI
Length:315
Mass (Da):35,780
Last modified:June 7, 2017 - v1
Checksum:i3E0BC6694D849747
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
NADR01000001 Genomic DNA Translation: OQP08071.1

Similar proteinsi

Entry informationi

Entry nameiA0A1V9BFF8_9BACI
AccessioniPrimary (citable) accession number: A0A1V9BFF8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: March 28, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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