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Protein

Probable L-aspartate decarboxylase

Gene

mfnA

Organism
Euryarchaeota archaeon ADurb.Bin190
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

L-aspartate = beta-alanine + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Pathwayi: coenzyme A biosynthesis

This protein is involved in the pathway coenzyme A biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway coenzyme A biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

UniPathwayi
UPA00241

Names & Taxonomyi

Protein namesi
Recommended name:
Probable L-aspartate decarboxylaseUniRule annotation (EC:4.1.1.11UniRule annotation)
Short name:
ADCUniRule annotation
Gene namesi
Name:mfnAUniRule annotationImported
ORF Names:BWY13_01350Imported
OrganismiEuryarchaeota archaeon ADurb.Bin190Imported
Taxonomic identifieri1852877 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeota

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei224N6-(pyridoxal phosphate)lysineUniRule annotation1

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family. MfnA subfamily.UniRule annotation

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
HAMAPiMF_01610 MfnA_decarbox, 1 hit
InterProiView protein in InterPro
IPR020931 MfnA
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
IPR021115 Pyridoxal-P_BS
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR03812 tyr_de_CO2_Arch, 1 hit
PROSITEiView protein in PROSITE
PS00392 DDC_GAD_HDC_YDC, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1V5XUT2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIEKGLPERE VMRLLEKTRE RDYSYDRFFS TMCTQPHPIA VKAHDMFLET
60 70 80 90 100
NLGDPGLFPG VAELEERVVA MLGELLGCPN ACGYVSTGGT ESNIQAIRAA
110 120 130 140 150
RNEAGIKDGN IVVPASAHFS FDKIGDLLSL EVRKAELDES LKVDLSSVQA
160 170 180 190 200
LLDEKTVALV GIAGSTEFGQ VDPIEDLASM AGERGIHMHV DAAFGGFVLP
210 220 230 240 250
FLKRKFKWDF SLPAVSSITI DPHKMGLSTI PAGGLLFRGA ECLSALETET
260 270 280 290 300
HYLTRARQAS LTGTRSGAAA AATYAVMMHL GREGFQKMVD YCMDLTAYLL
310 320 330 340 350
AGARKMGIEP VIEPVMNVVA LSVPSPAAVR EELMKLNWHV SMTREPNRAL
360 370
RLILMGHMSR EKIDLFLADL EAVLLKL
Length:377
Mass (Da):41,180
Last modified:June 7, 2017 - v1
Checksum:i42F553793CDF5F26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MWCS01000261 Genomic DNA Translation: OQB19373.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MWCS01000261 Genomic DNA Translation: OQB19373.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayi
UPA00241

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
HAMAPiMF_01610 MfnA_decarbox, 1 hit
InterProiView protein in InterPro
IPR020931 MfnA
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
IPR021115 Pyridoxal-P_BS
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR03812 tyr_de_CO2_Arch, 1 hit
PROSITEiView protein in PROSITE
PS00392 DDC_GAD_HDC_YDC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1V5XUT2_9EURY
AccessioniPrimary (citable) accession number: A0A1V5XUT2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: October 10, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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