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Protein
Submitted name:

Poly(A) polymerase alpha isoform A

Gene

PAPOLA

Organism
Patagioenas fasciata monilis
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions. Also active with manganese.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei152ATPUniRule annotation1
Metal bindingi156Magnesium 1; catalyticUniRule annotation1
Metal bindingi156Magnesium 2; catalyticUniRule annotation1
Metal bindingi158Magnesium 1; catalyticUniRule annotation1
Metal bindingi158Magnesium 2; catalyticUniRule annotation1
Metal bindingi210Magnesium 2; catalyticUniRule annotation1
Binding sitei210ATPUniRule annotation1
Binding sitei271ATPUniRule annotation1
Binding sitei280ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi143 – 145ATPUniRule annotation3
Nucleotide bindingi156 – 158ATPUniRule annotation3
Nucleotide bindingi289 – 290ATPUniRule annotation2

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingUniRule annotation, MagnesiumUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Poly(A) polymerase alpha isoform AImported
Gene namesi
Name:PAPOLAImported
ORF Names:AV530_009932Imported
OrganismiPatagioenas fasciata monilisImported
Taxonomic identifieri372326 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeColumbiformesColumbidaePatagioenas
Proteomesi
  • UP000190648 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 406PAP_centralInterPro annotationAdd BLAST343
Domaini130 – 217NTP_transf_2InterPro annotationAdd BLAST88
Domaini409 – 477PAP_RNA-bindInterPro annotationAdd BLAST69
Domaini469 – 548PAP_RNA-bindInterPro annotationAdd BLAST80

Family and domain databases

InterProiView protein in InterPro
IPR011068 NuclTrfase_I-like_C
IPR007012 PolA_pol_cen_dom
IPR007010 PolA_pol_RNA-bd_dom
IPR014492 PolyA_polymerase
IPR002934 Polymerase_NTP_transf_dom
PANTHERiPTHR10682 PTHR10682, 1 hit
PfamiView protein in Pfam
PF01909 NTP_transf_2, 1 hit
PF04928 PAP_central, 1 hit
PF04926 PAP_RNA-bind, 2 hits
PIRSFiPIRSF018425 PolyA_polymerase, 1 hit
SUPFAMiSSF55003 SSF55003, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1V4KC93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAAPLTRT EPGHVRWRSA APGGFRAIPV GLGAGVRLLC AWSWGTSPVT
60 70 80 90 100
TQGSQTQQLQ KHYGITSPIS LAAPKESDCM LTQKLIETLK PYGVFEEEEE
110 120 130 140 150
LQRRILILGK LNNLVKEWIR EISESKNLPQ SVIENVGGKI FTFGSYRLGV
160 170 180 190 200
HTKGADIDAL CVAPRHVERS DFFTSFYEKL KQQEEVKDLR AVEEAFVPVI
210 220 230 240 250
KLCFDGIEID ILFARLALQT IPEDLDLRDD SLLKNLDIRC IRSLNGCRVT
260 270 280 290 300
DEILHLVPNI DNFRLTLRAI KLWAKRHNIY SNILGFLGGV SWAMLVARTC
310 320 330 340 350
QLYPNAIAST LVHKFFLVFS KWEWPNPVLL KQPEECNLNL PVWDPRVNPS
360 370 380 390 400
DRYHLMPIIT PAYPQQNSTY NVSVSTRMVM VEEFKQGLAI TDEILLSKAE
410 420 430 440 450
WSKLFEAPNF FQKYKHYIVL LASAPTEKQR LEWVGLVESK IRILVGNLEK
460 470 480 490 500
NEFITLAHVN PQSFPAPKEN PDKEEYRTMW VIGLVFKKTE NSENLSVDLT
510 520 530 540 550
YDIQSFTDTV YRQAINSKMF EMDMKIAARH VKRKQLHQLL PSHVLQKKKK
560 570 580 590 600
HSTEGIRLAA LNDSSLDLSM DSDNSTSVPS PTSAMKTSPL NSSGSSQGRS
610 620 630 640 650
SPAPAVTAAS VTNIQASEVT VPQINSSESS GGTSNESIPQ TATQPAISPP
660 670 680 690 700
PKPTISRIVS SAYLLNPSPR TSGNVATKMP SPVTAVKRTS SPHKEESPKK
710 720 730 740 750
MKIEEDEISE DTSCIDLNEH EKMETKEQLE TEVNVNSQTE TLQTTSLQAP
760 770 780
QKTPSTDLSD IPALPANPIP VIKNSIKLRL NR
Length:782
Mass (Da):87,408
Last modified:June 7, 2017 - v1
Checksum:iBE43A6A07AEAD140
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LSYS01003973 Genomic DNA Translation: OPJ81497.1

Similar proteinsi

Entry informationi

Entry nameiA0A1V4KC93_PATFA
AccessioniPrimary (citable) accession number: A0A1V4KC93
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: December 20, 2017
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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