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Protein

Caveolin

Gene

CAV1

Organism
Alligator sinensis (Chinese alligator)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.UniRule annotationSAAS annotation

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
CaveolinUniRule annotation
Gene namesi
Name:CAV1Imported
OrganismiAlligator sinensis (Chinese alligator)Imported
Taxonomic identifieri38654 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaCrocodyliaAlligatoridaeAlligatorinaeAlligator
Proteomesi
  • UP000189705 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei117 – 144HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Golgi apparatusUniRule annotationSAAS annotation, Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the caveolin family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

KOiK06278

Family and domain databases

InterProiView protein in InterPro
IPR015504 CAV-1
IPR001612 Caveolin
IPR018361 Caveolin_CS
PANTHERiPTHR10844 PTHR10844, 1 hit
PTHR10844:SF18 PTHR10844:SF18, 1 hit
PfamiView protein in Pfam
PF01146 Caveolin, 1 hit
PROSITEiView protein in PROSITE
PS01210 CAVEOLIN, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1U8DDZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLKKEIQLL KHVMVLLDTS FQKRKQQLHF LCDKFILAVS ETFFQRNWLA
60 70 80 90 100
RDSSWDSFVK FLTPNLKSRN GNINTSKELQ IDFEDVIAEP EGTHSFDGIW
110 120 130 140 150
KASFTTFTVT KYWFYRLLAA IFGIPLALIW GIYFAILSFL HIWAVVPCIR
160 170 180 190
SYLIEIQCIS RVYSICIHTF CDPLFEAIGK IFSSIQATVR KEI
Length:193
Mass (Da):22,558
Last modified:May 10, 2017 - v1
Checksum:iFD21C9C9D4E16B80
GO

Sequence databases

RefSeqiXP_014375425.1, XM_014519939.1

Genome annotation databases

GeneIDi102368943
KEGGiasn:102368943

Similar proteinsi

Entry informationi

Entry nameiA0A1U8DDZ4_ALLSI
AccessioniPrimary (citable) accession number: A0A1U8DDZ4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: July 18, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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