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Protein

Homeobox protein cut-like

Gene

Cux1

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1230 – 1289HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein cut-likeUniRule annotation
Gene namesi
Name:Cux1Imported
OrganismiMesocricetus auratus (Golden hamster)Imported
Taxonomic identifieri10036 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
Proteomesi
  • UP000189706 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini553 – 640CUTInterPro annotationAdd BLAST88
Domaini920 – 1007CUTInterPro annotationAdd BLAST88
Domaini1103 – 1190CUTInterPro annotationAdd BLAST88
Domaini1228 – 1288HomeoboxInterPro annotationAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili17 – 37Sequence analysisAdd BLAST21
Coiled coili68 – 88Sequence analysisAdd BLAST21
Coiled coili112 – 196Sequence analysisAdd BLAST85
Coiled coili201 – 228Sequence analysisAdd BLAST28
Coiled coili237 – 274Sequence analysisAdd BLAST38
Coiled coili296 – 330Sequence analysisAdd BLAST35
Coiled coili335 – 355Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the CUT homeobox family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotation

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR003350 CUT_dom
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376 CUT, 3 hits
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM01109 CUT, 3 hits
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 3 hits
PROSITEiView protein in PROSITE
PS51042 CUT, 3 hits
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1U8CCR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR
60 70 80 90 100
EFKKNTPEDL RKQVAPLLKS FQGEIDALSK RSKEAEAAFL TVYKRLIDVP
110 120 130 140 150
DPAPALDLGQ QLEIKVQRLH DIETENQKLR ETLEEYNKEF AEVKNQEVTI
160 170 180 190 200
KALKEKIREY EQTLKSQAET IALEKEQKLQ NDFAEKERKL QETQMSTTSK
210 220 230 240 250
LEEAEHKLQT LQTALEKTRT ELFDLKTKYD EETTAKADEM EMIMTDLERA
260 270 280 290 300
NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVEQA IEVLTRSSLE
310 320 330 340 350
VELAAKEREI AQLVEDVQRL QASLTKLREN SASQISQLEQ QLSAKNSTLK
360 370 380 390 400
QLEEKLRGQA DYEEVKKELN TLKSMEFAPA EGAGTQDSTK PLEVLLLEKN
410 420 430 440 450
RSLQSENATL RISNSDLSGS ARRKGRDQPE SRRPGPLPAS PPPQLPRNTG
460 470 480 490 500
EQVSNTNGTH HFSPAGLSQD FFSSNMASPS LPLASTGKFA LNSLLQRQLM
510 520 530 540 550
QSFYSKAMQE AGSTSTIFST GPYSTNSISS PSPLQQSPDV NGMAPSPSQS
560 570 580 590 600
ESAGSVSEGE EIDTAEIARQ VKEQLIKHNI GQRIFGHYVL GLSQGSVSEI
610 620 630 640 650
LARPKPWNKL TVRGKEPFHK MKQFLSDEQN ILALRSIQGR QRGNITTRIR
660 670 680 690 700
ASETGSDEAI KSILEQAKRE LQVQKTAEPA QPSSASSSGN SDDAIRSILQ
710 720 730 740 750
QARREMEAQQ AALDPTLKPA PLSQPELAVL TPKLLSASPM PTVPSYPPLA
760 770 780 790 800
IPLKKTPAAP EATASALPSA PALKKEAQDA PGLDPAGSTD AAQGVLRQVK
810 820 830 840 850
SELVRGSTWK DPWWSPVQPE RRNLTSCEET KADEASASGK EKASSSQPRA
860 870 880 890 900
ERSQLQGPSS SAEYWKEWPS AESPYSQSSE LSLTGASRSE TPQNSPLPSS
910 920 930 940 950
PIVPMAKPAK PSVPPLTPEQ YEVYMYQEVD TIELTRQVKE KLAKNGICQR
960 970 980 990 1000
IFGEKVLGLS QGSVSDMLSR PKPWSKLTQK GREPFIRMQL WLNGELGQGV
1010 1020 1030 1040 1050
LPVQGQQQGP VLHSVTSLQD PLQQGCVSSE STPKTSASCS PAPESPMSSS
1060 1070 1080 1090 1100
ESVKSLTELV QQPCPAIETS KEGKPPEPSD PPASDSQPTT PLPLSGHSAL
1110 1120 1130 1140 1150
SIQELVAMSP ELDTYGITKR VKEVLTDNNL GQRLFGETIL GLTQGSVSDL
1160 1170 1180 1190 1200
LARPKPWHKL SLKGREPFVR MQLWLNDPNN VEKLMDMKRM EKKAYMKRRH
1210 1220 1230 1240 1250
SSVSDTQPCE PPSVGIDYSQ GASPQPQQQL KKPRVVLAPE EKEALKRAYQ
1260 1270 1280 1290 1300
QKPYPSPKTI EELATQLNLK TSTVINWFHN YRSRIRRELF IEEIQAGSQG
1310 1320 1330 1340 1350
QAGASDSPSA RSGRAAPSSE GDSCDGVEAA DVEEPGGTTV ATKSQGGPAE
1360 1370 1380 1390 1400
VAAAPADREE AAQPAEKAKA QPLSSATPGQ DDGDDAGRPR PPPEGPADTP
1410 1420 1430 1440 1450
APVPNLAAPA PGEDAATSAT ATAPEARGAA RAGPAERSSA LPSTSAPATA
1460 1470 1480 1490 1500
PARRPSSLQS LFGLPEAAGA RDNPVRKKKA ANLNSIIHRL EKAASREEPI

EWEF
Length:1,504
Mass (Da):164,355
Last modified:May 10, 2017 - v1
Checksum:iA94D9AF342AF2000
GO

Sequence databases

RefSeqiXP_012976240.1, XM_013120786.1

Genome annotation databases

GeneIDi101826647

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_012976240.1, XM_013120786.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi101826647

Organism-specific databases

CTDi1523

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR003350 CUT_dom
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376 CUT, 3 hits
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM01109 CUT, 3 hits
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 3 hits
PROSITEiView protein in PROSITE
PS51042 CUT, 3 hits
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1U8CCR7_MESAU
AccessioniPrimary (citable) accession number: A0A1U8CCR7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: April 25, 2018
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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