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Entry version 8 (13 Feb 2019)
Sequence version 1 (10 May 2017)
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Protein
Submitted name:

collagen alpha-1(XXVII) chain isoform X6

Gene

Col27a1

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
collagen alpha-1(XXVII) chain isoform X6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Col27a1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMesocricetus auratus (Golden hamster)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10036 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000189706 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 39Sequence analysisAdd BLAST39
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501055854840 – 1799Sequence analysisAdd BLAST1760

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1599 – 1799Fibrillar collagen NC1InterPro annotationAdd BLAST201

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

CollagenImported, SignalSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR000885 Fib_collagen_C
IPR001791 Laminin_G

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01410 COLFI, 2 hits
PF01391 Collagen, 9 hits

ProDom; a protein domain database

More...
ProDomi
View protein in ProDom or Entries sharing at least one domain
PD002078 Fib_collagen_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00038 COLFI, 1 hit
SM00210 TSPN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899 SSF49899, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51461 NC1_FIB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

A0A1U8CAG8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGTGSAQGAR GTAAAGHWGG FLFAWILVSF ACHLASTQGA PEDVDVLQRL
60 70 80 90 100
GLSWTKAGGG RSPAPPGVIP FPSGFIFTQR ARLQAPTATV LPTSLGQELA
110 120 130 140 150
LVLSLCSHRV NHAFLFAIRS REHRLQLGLQ FLPGRTLVHL GPRQSVAFNL
160 170 180 190 200
DVHDGRWHHL ALELRGRTVT LVTACGQHRV PIPLPSRRDS VLDPQGSFLL
210 220 230 240 250
GKMNPRAVQF EGALCQFSVH PVAQVARNYC AHLRERCRQV DTYGPQVGAL
260 270 280 290 300
FPWDSGPAFA LRPEPAFLGL GNLTRAPATL GARPVVRGPM MTMAPAMPTK
310 320 330 340 350
PLRIVPPDVP QHSSAQTPLG LAKQSARKAS SPPPSASLAS STQPRQITVT
360 370 380 390 400
SPTKRPPTKP SPSSLSVTPV EGPHPSQKAA VPSSTNPAVL PAQKLVTRTP
410 420 430 440 450
HLAPSKASSP TVRPVQKTFV TPRPLSPSPQ PLCPTAGLVK KSTLPTVAES
460 470 480 490 500
KSKTSSWASK PVHTSAPKSI QQTVVSQSPV PYLISARASL TLATALPPLG
510 520 530 540 550
AGNPRMALPT RDSSSTPAGS KRFTGLEASK KTRPKSGPRK PIPLSPEKTA
560 570 580 590 600
RDTPPRDLTT RPSQPSTPAL VLAPAHLLSS SPRPTSGSFP FFYLPGPTPF
610 620 630 640 650
PMLMGPPGSK GDCGLPGPPG LPGLPGSPGA RGPRGPPGPY GNPGPPGPPG
660 670 680 690 700
AKGQKGDPGL SPGQAHDGAK GNMGLPGLSG NPGPLGRKGQ KGHPGAAGHP
710 720 730 740 750
GEQGQPGPEG SPGAKGYPGR QGFPGPVGDP GPKGSRGYIG LPGLFGLPGS
760 770 780 790 800
DGERGLPGVP GKRGEMGRPG FPGNSGERGP PGLDGNPGEI GLPGPPGVPG
810 820 830 840 850
LIGDMGALGP IGYPGPKGMK GLMGGVGEPG LKGDKGEQGI PGVSGDPGFQ
860 870 880 890 900
GDKGSQGLPG LPGARGKPGP LGKAGDKGSL GFPGPPGPEG FPGDIGPPGD
910 920 930 940 950
NGPEGMKGKP GARGLPGPPG LLGPEGDEGP MGPPGVPGVE GQPGRKGFPG
960 970 980 990 1000
RPGPDGSKGE PGDPGRPGPV GEQGLMGFIG LVGEPGIMGE KGDRGVMGPP
1010 1020 1030 1040 1050
GAPGPKGSMG HPGTPGGIGD PGEPGSRGPP GSRGPPGMRG AKGRRGPRGP
1060 1070 1080 1090 1100
DGPAGEQGSK GLKGRAGPRG RPGQPGQQGA AGERGHLGAR GFPGIPGPSG
1110 1120 1130 1140 1150
PPGAKGLPGE PGSQGPQGPV GPPGEMGPKG PPGAVGEPGL PGDSGMKGDL
1160 1170 1180 1190 1200
GPLGPPGEQG LIGQRGEPGL EGDLGPMGPD GLKGDKGDPG PDGERGEKGQ
1210 1220 1230 1240 1250
EGLKGEEGLP GPPGIVGVRG PEGKPGRQGP MGAPGRMGAQ GDPGLAGYNG
1260 1270 1280 1290 1300
HKGITGPLGP PGPKGEKGEQ GEDGNAEGPP GPPGDRGPVG DRGDRGEPGD
1310 1320 1330 1340 1350
PGYPGQEGVQ GLRGKPGQQG QPGHPGPRGQ PGPKGSKGEE GPKGKPGKAG
1360 1370 1380 1390 1400
ASGRRGTQGL QGLPGPRGVV GRQGPEGMDG PDGTPGRDGR PGYQGQQGDD
1410 1420 1430 1440 1450
GTPGPVGPAG RRGNPGVAGL PGAQGPPGFK GESGLPGQLG PPGKRGTEGG
1460 1470 1480 1490 1500
TGLPGNQGEP GSKGQPGDSG EMGFPGVAGL LGPKGPPGDI GFKGIQGPRG
1510 1520 1530 1540 1550
PPGLMGKEGI IGPPGMLGPA GLPGPKGDRG SRGDWGLQGP KGPPGPRGRP
1560 1570 1580 1590 1600
GPPGPPWHPV QFQQDDLGAT FQTWMDAHRA VRPEQGYSYP DQLVLDQGGE
1610 1620 1630 1640 1650
IFKTLHYLSN LIQSIKTPLG TKENPARVCR DLMDCEQRMA DGTYWVDPNL
1660 1670 1680 1690 1700
GCSSDTIEVS CNFTHGGQTC LKPLTASKVE FAVSRVQMNF LHLLSSEGTQ
1710 1720 1730 1740 1750
HITIHCLNLT VWQEDPGRPS ARRAVRFRAW NGQVFEAGGQ FRPEVSVDGC
1760 1770 1780 1790
KVHDGRWHRT LFTFRTQDPQ QLPIVSVDNL PPVSSGKQYR LEVGPACFL
Length:1,799
Mass (Da):181,647
Last modified:May 10, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF0DD683A409FE07D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1U8BZC0A0A1U8BZC0_MESAU
collagen alpha-1(XXVII) chain isofo...
Col27a1
1,841Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1U8C9W1A0A1U8C9W1_MESAU
collagen alpha-1(XXVII) chain isofo...
Col27a1
1,839Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1U7QJC2A0A1U7QJC2_MESAU
collagen alpha-1(XXVII) chain isofo...
Col27a1
1,840Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1U8BZB1A0A1U8BZB1_MESAU
collagen alpha-1(XXVII) chain isofo...
Col27a1
1,840Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1U8C2F2A0A1U8C2F2_MESAU
collagen alpha-1(XXVII) chain isofo...
Col27a1
1,553Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q0CYK9A0A3Q0CYK9_MESAU
collagen alpha-1(XXVII) chain isofo...
Col27a1
1,840Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_012972579.1, XM_013117125.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
101840376

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_012972579.1, XM_013117125.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi101840376

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
85301

Family and domain databases

InterProiView protein in InterPro
IPR008160 Collagen
IPR013320 ConA-like_dom_sf
IPR000885 Fib_collagen_C
IPR001791 Laminin_G
PfamiView protein in Pfam
PF01410 COLFI, 2 hits
PF01391 Collagen, 9 hits
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002078 Fib_collagen_C, 1 hit
SMARTiView protein in SMART
SM00038 COLFI, 1 hit
SM00210 TSPN, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS51461 NC1_FIB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1U8CAG8_MESAU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1U8CAG8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: February 13, 2019
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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