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Protein

Protein transport protein sec16

Gene

Sec16b

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization.UniRule annotation

GO - Biological processi

Keywordsi

Biological processER-Golgi transportUniRule annotation, Protein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein sec16UniRule annotation
Gene namesi
Name:Sec16bImported
OrganismiMesocricetus auratus (Golden hamster)Imported
Taxonomic identifieri10036 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
Proteomesi
  • UP000189706 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Golgi apparatusUniRule annotation, MembraneUniRule annotation

Interactioni

Subunit structurei

SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini287 – 383Sec16InterPro annotationAdd BLAST97
Domaini452 – 685Sec16_CInterPro annotationAdd BLAST234

Sequence similaritiesi

Belongs to the SEC16 family.UniRule annotation

Family and domain databases

CDDicd09233 ACE1-Sec16-like, 1 hit
InterProiView protein in InterPro
IPR024298 ACE1_Sec16_Sec31
IPR024880 Sec16
IPR024340 Sec16_CCD
PfamiView protein in Pfam
PF12932 Sec16, 1 hit
PF12931 Sec16_C, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A1U8C206-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPWVPQWSS QPQVRPKTPS KDANRGLLSG HYRPRPHPRY SGDKYHQGQD
60 70 80 90 100
AQRSSKSQQD PKAQDHRAQD PRDDQQQVRY VPRPGGWSQP VSGSNYLEGS
110 120 130 140 150
YPNQLYSRPG YEDPYRRYHT PTPREEYAYG NYYYKGHPQL LQEERVARQG
160 170 180 190 200
SPYIWNEDYG DQKYFNEHHG EKHNSPFGTK SENQFHTSKN PYEDSLASIF
210 220 230 240 250
GQEQPGEFFP ESEAQKQKSS LTSRSNLLQQ HESGLSSSSY ELSQYMTDVP
260 270 280 290 300
EQYEPVVSAA WRPIQADDAS ATNPKTLRKF CVPHMSVSFG PGGQLVCVIP
310 320 330 340 350
NSPADGQTAL VEVHSMEVIL NDSEDQEEMR SFPGPLTRED IHKVDIMTFC
360 370 380 390 400
QQKAAQCLKS ETPGSRDSAL LWQLLVLLCR QNGSMVGSDI AELLMQDCRK
410 420 430 440 450
LEKYKKQPPV ANLINLTDED WLVPRSGTRN LLTGEIPPSV ETPAQIVEKF
460 470 480 490 500
TKLLYYGRKK EALEWAMKNH LWGHALFLAS KMDPRTYNWV MSGFTSTLAL
510 520 530 540 550
NDPLQTLFQL MSGRIPQAAM CCGDKQWGDW RPHLAVILSN QAGDTEVYQR
560 570 580 590 600
SIVSMGDTLA GKGLVEAAHF CYLMAQAPFG HYTAKTDLLA LLGSNHSQEF
610 620 630 640 650
LKFATIEAIQ RTEIFEYCQM LGRPKSFIPS FQVYKLLYAS RLADYGLASQ
660 670 680 690 700
ALHYCEAIGE AVLSQGGSSH PVLLAELIKL AEKLKLSDPL VLERRPGDRD
710 720 730 740 750
LEPDWLVQLR RRHKELEQNK TGDYSDPDSI HSDIYGTRGT PDTPYRDLSG
760 770 780 790 800
YQSYSGDPGF NSAPWPTPEQ TGLTQPIPHQ PFPLHRDACS EREGENTAPQ
810 820 830 840 850
EPLQDPDGLE VSSPQAPQAP RTGRFSEDST ISSKKDEEAS SDEADEPSHQ
860 870 880 890 900
DASQRGKPGD GKENTKSSGF GWFSWFRSKP ANSVSPSGDE DSSDISDSEQ
910 920 930 940 950
ESSSPSPPRH IGLGLSPTPS VESPSPLDAS TFSRGIGGSN LPGSSNNSGT
960 970 980 990 1000
AEVTRIGSVL GPQGVSSEFY SQPGALPPPP TLQGAVPLYN PSQVPQLSTT
1010
TSLSRPNRLA QRRYPTQPC
Length:1,019
Mass (Da):113,433
Last modified:May 10, 2017 - v1
Checksum:i8BA4E1E3945A234C
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1U8BR35A0A1U8BR35_MESAU
Protein transport protein sec16
Sec16b
1,071Annotation score:
A0A1U8BRF9A0A1U8BRF9_MESAU
Protein transport protein sec16
Sec16b
1,070Annotation score:
A0A1U8C2K6A0A1U8C2K6_MESAU
Protein transport protein sec16
Sec16b
1,001Annotation score:

Sequence databases

RefSeqiXP_012969808.1, XM_013114354.1

Genome annotation databases

GeneIDi101838479

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_012969808.1, XM_013114354.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi101838479

Organism-specific databases

CTDi89866

Family and domain databases

CDDicd09233 ACE1-Sec16-like, 1 hit
InterProiView protein in InterPro
IPR024298 ACE1_Sec16_Sec31
IPR024880 Sec16
IPR024340 Sec16_CCD
PfamiView protein in Pfam
PF12932 Sec16, 1 hit
PF12931 Sec16_C, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1U8C206_MESAU
AccessioniPrimary (citable) accession number: A0A1U8C206
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: November 22, 2017
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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