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Protein
Submitted name:

collagen alpha-1(XVIII) chain isoform X2

Gene

Col18a1

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
collagen alpha-1(XVIII) chain isoform X2Imported
Gene namesi
Name:Col18a1Imported
OrganismiMesocricetus auratus (Golden hamster)Imported
Taxonomic identifieri10036 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
Proteomesi
  • UP000189706 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_501051883327 – 1517Sequence analysisAdd BLAST1491

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini235 – 423LAM_G_DOMAINInterPro annotationAdd BLAST189

Keywords - Domaini

CollagenSAAS annotationImported, SignalSequence analysis

Family and domain databases

CDDicd00247 Endostatin-like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186 C-type_lectin-like/link_sf
IPR039075 COL18A1
IPR008160 Collagen
IPR010515 Collagenase_NC10/endostatin
IPR013320 ConA-like_dom_sf
IPR016187 CTDL_fold
IPR010363 DUF959_COL18_N
IPR001791 Laminin_G
PANTHERiPTHR45362 PTHR45362, 1 hit
PfamiView protein in Pfam
PF01391 Collagen, 4 hits
PF06121 DUF959, 1 hit
PF06482 Endostatin, 1 hit
SMARTiView protein in SMART
SM00210 TSPN, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
SSF56436 SSF56436, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.iShow all

A0A1U8BTB6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPDPSRRLW LLLLLLLSCC LEPARPDRNP LNPLNPLSPL VWLWSTKTND
60 70 80 90 100
PISEPKSSSP VEPTESPTTH AVPQDGLAEQ QTARANPKLP PEDQEAGQSG
110 120 130 140 150
TPTTTATPIP PMASAASPDM KEENVAGVGA KILNVAQGIR SFVQLWDENP
160 170 180 190 200
ATKKSAGMEA SASSIPSALL TPTEFSSAPQ EGDTTLWLNR GVPSSPDVQT
210 220 230 240 250
TEAGTLTVPT QPPPSLSSLQ APLRRPTPPE NVAEEVGLPQ LLGDPLPQQI
260 270 280 290 300
TQIDDPHVGP VYIFGRDSSS SQTAQHHFPR LFFRDFSLLF HIQPATKAAG
310 320 330 340 350
VLFAITDTVQ KVVSLGVKLS GVQNGHQNIS LLYTEPGATQ TQTGASFHLP
360 370 380 390 400
AFVGQWTHFV LSVDGGSVTL YVDCEEFQRV PFARSPQGLE LEHGSGLFVG
410 420 430 440 450
QAGAADPDKF QGKISELKVR QNPRVSPVLC SDEDGDDEDR ASGDFGSGFE
460 470 480 490 500
ESSKPHREED TSLAPSLPQP PPVTSPPLAG GSTTEDSRTE ETEEETTVDS
510 520 530 540 550
IGAETLPGTD SSRARDESVQ NHGGGLIKGG LKGQKGEPGA RGLPGPAGPQ
560 570 580 590 600
GPAGPVIQSP IAQPVPGAQG PPGPQGPPGK DGAPGRDGEP GDPGEDGRPG
610 620 630 640 650
DAGPQGFPGT PGDVGPKGEK GDPGVGARGP PGPPGPPGPS FRQDKLTFID
660 670 680 690 700
MEGSGFSGDL ESLRGPRGFP GPPGPPGVPG LPGEPGRFGV NSSYAPGPAG
710 720 730 740 750
LPGVPGKEGP PGFPGPPGPP GPPGKVGPPG EAGQKGNVGE VGIPGPKGSK
760 770 780 790 800
GDLGPVGVPG KTGMAGPPGP TGPPGPPGPP GPPGPGFAAG FDDMEGSGIP
810 820 830 840 850
FWSTARSSEG LQGPPGLPGL KGDPGVTGPP GAKGEVGAEG VQGMPGLPGR
860 870 880 890 900
AGAAGSPGPK GEKGSQGEKG SPGKDGVGLP GLPGPPGPPG PVLYVSNEDR
910 920 930 940 950
AVVTTPGPEG KPGYAGFPGP AGPKGDLGSK GEQGLPGPKG EKGEPGAIFG
960 970 980 990 1000
PDGRALGHAQ KGAKGEPGFR GPPGPYGRPG HKGEIGFPGR PGRPGTNGLK
1010 1020 1030 1040 1050
GEKGEPGDAS LGFSMRGLPG PPGPPGPPGP PGMPIYDSNA FVESGRPGLP
1060 1070 1080 1090 1100
GQQGVQGPSG PKGDKGEVGP PGPPGQFPID FFNLGAEMKG DKGDRGDTGQ
1110 1120 1130 1140 1150
KGERGEPGVA GGGFFSSSVP GPPGPPGYPG IPGPKGESIR GPPGPPGPQG
1160 1170 1180 1190 1200
PPGIGYEGRQ GPPGPPGPPG PPSFPGPHRQ TVSVPGPPGP PGPPGPPGAM
1210 1220 1230 1240 1250
GASAGVRIWA TYQTMLDKVR EVPEGWLIFV AEREELYVRV RNGFRKVLLE
1260 1270 1280 1290 1300
ARTALPHGTG NEVAALQPPL VQLHEGSPYT RREHSYSTAR PWRADDILAN
1310 1320 1330 1340 1350
PPRLPEPQPY PGVPHHHSSS VHQPPAHPTG SPAHTHHDFQ PVLHLVALNS
1360 1370 1380 1390 1400
PLSGGMRGIR GADFQCFQQA RAVGLAGTFR AFLSSRLQDL YSIVRRADRG
1410 1420 1430 1440 1450
TVPIVNLKDE VLSPSWDALF SGSQGQLQPG ARIFSFDGRD VLRHPVWPQK
1460 1470 1480 1490 1500
SIWHGSDPSG RRLMESYCET WRTEATGATG QASSLLSGRL LEQKAASCHN
1510
TYIVLCIENS FMTSFSK
Length:1,517
Mass (Da):155,182
Last modified:May 10, 2017 - v1
Checksum:iFCA447BCFB4DBC9B
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1U8C1A8A0A1U8C1A8_MESAU
collagen alpha-1(XVIII) chain isofo...
Col18a1
1,518Annotation score:
A0A1U8BQ55A0A1U8BQ55_MESAU
collagen alpha-1(XVIII) chain isofo...
Col18a1
1,322Annotation score:
A0A1U8BPT3A0A1U8BPT3_MESAU
collagen alpha-1(XVIII) chain isofo...
Col18a1
1,508Annotation score:

Sequence databases

RefSeqiXP_012969355.1, XM_013113901.1

Genome annotation databases

GeneIDi101836799

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_012969355.1, XM_013113901.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi101836799

Organism-specific databases

CTDi80781

Family and domain databases

CDDicd00247 Endostatin-like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186 C-type_lectin-like/link_sf
IPR039075 COL18A1
IPR008160 Collagen
IPR010515 Collagenase_NC10/endostatin
IPR013320 ConA-like_dom_sf
IPR016187 CTDL_fold
IPR010363 DUF959_COL18_N
IPR001791 Laminin_G
PANTHERiPTHR45362 PTHR45362, 1 hit
PfamiView protein in Pfam
PF01391 Collagen, 4 hits
PF06121 DUF959, 1 hit
PF06482 Endostatin, 1 hit
SMARTiView protein in SMART
SM00210 TSPN, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
SSF56436 SSF56436, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1U8BTB6_MESAU
AccessioniPrimary (citable) accession number: A0A1U8BTB6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: September 12, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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