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Protein
Submitted name:

alpha-1-antitrypsin isoform X1

Gene

Serpina1

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
alpha-1-antitrypsin isoform X1Imported
Gene namesi
Name:Serpina1Imported
OrganismiMesocricetus auratus (Golden hamster)Imported
Taxonomic identifieri10036 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
Proteomesi
  • UP000189706 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501055250525 – 412Sequence analysisAdd BLAST388

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 410SERPINInterPro annotationAdd BLAST357

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1U8BK25-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKPSISWGIL LLAGLCCLVP SFLAEDAQET DASKQDQEHQ ACCKIAPNLA
60 70 80 90 100
DFSFNLYREL VHQSNTTNIF FSPVSIATAF AMLSLGTKGV THTQILEGLG
110 120 130 140 150
FNLTEIAEAE VHKGFHNLLQ TFNRPDNELQ LTTGNGLFIH NNLKLVDKFL
160 170 180 190 200
EEVKNSYHSE AFSVNFTDSE EAKKVINGFV EKGTQGKIVD LVKDLDKDTV
210 220 230 240 250
LALVNYIFFK GKWKKPFDAD NTEEADFHVD KTTTVKVPMM SRLGMFDVHH
260 270 280 290 300
CSTLSSWVLL MDYLGNATAI FILPDDGKMQ HLEQTLNKEI IGKFLKDRHT
310 320 330 340 350
RSANVHFPKL SISGTYNLKT ALDPLGITQV FSNGADLSGI TEDVPLKLGK
360 370 380 390 400
AVHKAVLTID ERGTEAAGAT FMEIIPMSVP PEVNFNSPFI AIIYDRQTKS
410
PLFVGKVVDP TR
Length:412
Mass (Da):45,698
Last modified:May 10, 2017 - v1
Checksum:i1682696D7425AEF1
GO

Sequence databases

RefSeqiXP_012967507.1, XM_013112053.1

Genome annotation databases

EnsembliENSMAUT00000011923; ENSMAUP00000008106; ENSMAUG00000009608
GeneIDi101841330

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_012967507.1, XM_013112053.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMAUT00000011923; ENSMAUP00000008106; ENSMAUG00000009608
GeneIDi101841330

Organism-specific databases

CTDi5265

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1U8BK25_MESAU
AccessioniPrimary (citable) accession number: A0A1U8BK25
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: June 20, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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