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Protein

Aminopeptidase

Gene

ERAP1

Organism
Tarsius syrichta (Philippine tarsier)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminopeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
AminopeptidaseUniRule annotation (EC:3.4.11.-UniRule annotation)
Gene namesi
Name:ERAP1Imported
OrganismiTarsius syrichta (Philippine tarsier)Imported
Taxonomic identifieri1868482 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniTarsiiformesTarsiidaeCarlito
Proteomesi
  • UP000189704 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_501054432033 – 937AminopeptidaseSequence analysisAdd BLAST905

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini260 – 520Peptidase_M1InterPro annotationAdd BLAST261
Domaini593 – 912ERAP1_CInterPro annotationAdd BLAST320

Sequence similaritiesi

Belongs to the peptidase M1 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

CDDicd09601 M1_APN_2, 1 hit
InterProiView protein in InterPro
IPR033520 ERAP1
IPR024571 ERAP1-like_C_dom
IPR034016 M1_APN-typ
IPR001930 Peptidase_M1
IPR014782 Peptidase_M1_N
PANTHERiPTHR11533 PTHR11533, 1 hit
PTHR11533:SF156 PTHR11533:SF156, 1 hit
PfamiView protein in Pfam
PF11838 ERAP1_C, 1 hit
PF01433 Peptidase_M1, 1 hit
PRINTSiPR00756 ALADIPTASE

Sequencei

Sequence statusi: Complete.

A0A1U7T614-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSPSLQWPL GTMSFLLPLL LSLLTVSTPS WCQSHEASDG TPFPWNKMRL
60 70 80 90 100
PEHVIPVHYD LTIHANLTTL TFQGTMEVEI TASQSTSTII LHSHYLQISK
110 120 130 140 150
ATLRKGAGEK PTEEPLRVLE HLPHEQIALL APEPLLVGFP YIVVIHYAGN
160 170 180 190 200
LSESLHGFYK STYRTTEGEV RILASTQFEP TAARMAFPCF DEPALKATFS
210 220 230 240 250
IKIRREPRHM AISNMPLVKS VTVAEGLIED HFDVTVKMST YLVAFIISDF
260 270 280 290 300
ESVSKMTKSG VKISVYAAPN KINQADYALE AAVTLLEFFE DYFNIPYPLP
310 320 330 340 350
KQDLAAIPDF QSGAMENWGL TTYRESSLLF DAETSSASSK LGITMIVAHE
360 370 380 390 400
LAHQWFGNLV TMEWWNDLWL NEGFAKFMEF VSVSVTHPEL KVEDYFFGKC
410 420 430 440 450
FNAMEVDALN SSHPVSTPVE NPAQIREMFD DVSYEKGACI LNMLREYLGA
460 470 480 490 500
DAFKSGIVQY LQKYSYKNTK NEDLWNSMAS ICPTDGTQGM DGFCSRSQHS
510 520 530 540 550
SSSSHWRQEG LDVKTMMNTW TLQKGFPLIT ITVRGRNVHM KQEHYMKGSD
560 570 580 590 600
DAPETGYLWH VPLTFTTSKS DMVHRFLLKT KTDVLILPEE VEWIKFNVGM
610 620 630 640 650
SGYYIVHYKD DGWDSLTGLL KGTHTAISSN DRASLINNAF QLVSIGKLPI
660 670 680 690 700
EKALDLTLYL KHETEIMPVF QGLNELIPMY KLMEKRDMNE VETQFKAFLI
710 720 730 740 750
RLLQGLIDKQ TWTDDGSVSE RMLRSQLLLL ACVRRYQPCV QRAEGYFRRW
760 770 780 790 800
KESNGNLSLP NDVTMAVFAV GAQNTEGWDF LYSKYQSSLS STKKSQIEFA
810 820 830 840 850
LCTSQNKEKL QWLLDQSFKG DIIKTQEFPH ILTLVGRNPV GYPLAWQFLR
860 870 880 890 900
ENWNKLIQKF DLGSSSIAYM VMGTTNQFST RTRLEEVKGF FSSLKENGSQ
910 920 930
LRCVQQTIET IEENIRWMDK NFDKIRVWLQ NEKLELL
Length:937
Mass (Da):106,828
Last modified:May 10, 2017 - v1
Checksum:i08ADCBECB99BE2BF
GO

Sequence databases

RefSeqiXP_008053235.1, XM_008055044.1

Genome annotation databases

EnsembliENSTSYT00000013775; ENSTSYP00000012638; ENSTSYG00000013775
GeneIDi103257319

Similar proteinsi

Entry informationi

Entry nameiA0A1U7T614_TARSY
AccessioniPrimary (citable) accession number: A0A1U7T614
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: February 28, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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