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Protein

Deoxyribonuclease

Gene

DNASE1

Organism
Alligator sinensis (Chinese alligator)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei100UniRule annotation1
Active sitei156UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotation, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
DeoxyribonucleaseUniRule annotation
Gene namesi
Name:DNASE1Imported
OrganismiAlligator sinensis (Chinese alligator)Imported
Taxonomic identifieri38654 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaCrocodyliaAlligatoridaeAlligatorinaeAlligator
Proteomesi
  • UP000189705 Componenti: Genome assembly

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501054317923 – 284DeoxyribonucleaseSequence analysisAdd BLAST262

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi123 ↔ 126UniRule annotation
Disulfide bondi195 ↔ 231Essential for enzymatic activityUniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 274Endo/exonuclease/phosphataseInterPro annotationAdd BLAST227

Sequence similaritiesi

Belongs to the DNase I family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK11994

Family and domain databases

Gene3Di3.60.10.10, 1 hit
InterProiView protein in InterPro
IPR018057 Deoxyribonuclease-1_AS
IPR016202 DNase_I
IPR033125 DNASE_I_2
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
PfamiView protein in Pfam
PF03372 Exo_endo_phos, 1 hit
PIRSFiPIRSF000988 DNase_I_euk, 1 hit
PRINTSiPR00130 DNASEI
SMARTiView protein in SMART
SM00476 DNaseIc, 1 hit
SUPFAMiSSF56219 SSF56219, 1 hit
PROSITEiView protein in PROSITE
PS00919 DNASE_I_1, 1 hit
PS00918 DNASE_I_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1U7SJJ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGAMKLVLSL LTVAYLLHTA ATLRISAFNI RTCGDTKLSN ETIAGIIVNI
60 70 80 90 100
LSMYDLIVVQ EVRDSDLSAV KKLMNKLNRM SPHLYSYVVS LPLGRTSYKE
110 120 130 140 150
QYLFIYRTGM MSVVDSYYYE DGCESCMNDT FSREPFIVKF SSPHTEVKEF
160 170 180 190 200
VLVPLHASPN EAAAEIDALY DVYLDVISKW ATDNILFLGD FNAGCSYVSP
210 220 230 240 250
EDWASIRLRT NRAFQWLIPD SADTTVSHTV CAYDRIVASG SEMKSCLIPE
260 270 280
TAHVNNFQRA FNLQYKDALA VSDHFPVEVT LRSF
Length:284
Mass (Da):31,988
Last modified:May 10, 2017 - v1
Checksum:iCCC6C126D74B5C2C
GO

Sequence databases

RefSeqiXP_006036898.1, XM_006036836.1

Genome annotation databases

GeneIDi102381685
KEGGiasn:102381685

Similar proteinsi

Entry informationi

Entry nameiA0A1U7SJJ2_ALLSI
AccessioniPrimary (citable) accession number: A0A1U7SJJ2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: February 28, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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