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Protein
Submitted name:

volume-regulated anion channel subunit LRRC8B

Gene

Lrrc8b

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
volume-regulated anion channel subunit LRRC8BImported
Gene namesi
Name:Lrrc8bImported
OrganismiMesocricetus auratus (Golden hamster)Imported
Taxonomic identifieri10036 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
Proteomesi
  • UP000189706 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 47HelicalSequence analysisAdd BLAST21
Transmembranei121 – 141HelicalSequence analysisAdd BLAST21
Transmembranei263 – 281HelicalSequence analysisAdd BLAST19
Transmembranei317 – 339HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 335Pannexin_likeInterPro annotationAdd BLAST335

Keywords - Domaini

Leucine-rich repeatSAAS annotation, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR025875 Leu-rich_rpt_4
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR038960 LRRC8
IPR021040 LRRC8_Pannexin-like
PANTHERiPTHR43945 PTHR43945, 1 hit
PfamiView protein in Pfam
PF12799 LRR_4, 1 hit
PF13855 LRR_8, 2 hits
PF12534 Pannexin_like, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 8 hits
PROSITEiView protein in PROSITE
PS51450 LRR, 11 hits

Sequencei

Sequence statusi: Complete.

A0A1U7QR28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITLTELKYL ADAESSYHIL KPWWDVFWYY ITLVMLLVAA LAGALQLTQT
60 70 80 90 100
RLLCCLPCKA EFGNHCAVPW DLLKASQNVS SSDADGSVRP PLRIQNDLHR
110 120 130 140 150
QQYAYVDAVC YEEQLHWFAK FFPYVVLLHT LIFAACSNFW LHYPSTSSRL
160 170 180 190 200
EHFVAILHKC FDSPWTTRAL SETVAEQSVR TLKPSKSKTL LSTSGGSAEA
210 220 230 240 250
DANKQALPYP QPGLESPGVE SPTSSVLDKK EGEQAKAIFE KVKRFRLHVE
260 270 280 290 300
QRDIIYRVYL KQIIVKVILF VVIIAYVPYF LSCITLEIDC LIDVQAFTGY
310 320 330 340 350
KRYQCVYSLA EIFKVLASFY VVLVILYGLT SSYSLWWMLR SSLKQYSFEA
360 370 380 390 400
LREKSNYSDI PDVKNDFAFI LHLADQYDPL YSKRFSIFLS EVSENKLKQI
410 420 430 440 450
SLNNEWTVEK LKSKLVRNSQ DKLELHLFML SGLPDNVFEL TEMEVLSLEL
460 470 480 490 500
IPEVKLPATV SQLVNLKELH LYHSSLVVDH PALAFLEGNL KILRLKFTEM
510 520 530 540 550
GKIPRWVFYL KNLKELYLSG CVLPEQLGTT QLEGFQDLKN LRTLYLKSNL
560 570 580 590 600
SRIPQVVTDL LPSLQKLSLD NEGSKLVVLN NLKKMVNLKS LELLSCDLER
610 620 630 640 650
IPHSIFSLNN LHELDLKENN LKTVEEVISF QHLPSLSCLK LWHNNIAYIP
660 670 680 690 700
AQIGALSNLE QLFLDHNNIE SLPLQLFLCT KLYYLDLSYN HLTFIPEEIQ
710 720 730 740 750
YLTNLQHFAV TNNNIEMLPD GLFQCKKLQY LLLGKNSLTD LSPLVGELSN
760 770 780 790 800
LTYLELIGNY LETLPPELEG CQSLKRSCLI VEDSLLNTLP LPVTERLQTC

LDKC
Length:804
Mass (Da):92,126
Last modified:May 10, 2017 - v1
Checksum:i1AC2D3A91B8C3820
GO

Sequence databases

RefSeqiXP_005077435.1, XM_005077378.1

Genome annotation databases

EnsembliENSMAUT00000001347; ENSMAUP00000001312; ENSMAUG00000000978
GeneIDi101844931

Similar proteinsi

Entry informationi

Entry nameiA0A1U7QR28_MESAU
AccessioniPrimary (citable) accession number: A0A1U7QR28
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: June 20, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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