UniProtKB - A0A1U7QK99 (A0A1U7QK99_MESAU)
Protein
Collagen-binding protein
Gene
Serpinh1
Organism
Mesocricetus auratus (Golden hamster)
Status
Functioni
GO - Molecular functioni
- collagen binding Source: InterPro
- serine-type endopeptidase inhibitor activity Source: InterPro
- unfolded protein binding Source: Ensembl
GO - Biological processi
- chondrocyte development involved in endochondral bone morphogenesis Source: Ensembl
- collagen biosynthetic process Source: Ensembl
- collagen fibril organization Source: Ensembl
- protein maturation Source: Ensembl
Keywordsi
Molecular function | ChaperoneARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Collagen-binding proteinARBA annotationAlternative name(s): Serpin H1ARBA annotation |
Gene namesi | Name:Serpinh1Imported |
Organismi | Mesocricetus auratus (Golden hamster)Imported |
Taxonomic identifieri | 10036 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Cricetidae › Cricetinae › Mesocricetus |
Proteomesi |
|
Subcellular locationi
Endoplasmic reticulum
- endoplasmic reticulum Source: UniProtKB-KW
Extracellular region or secreted
- extracellular space Source: InterPro
Other locations
- endoplasmic reticulum-Golgi intermediate compartment Source: Ensembl
- membrane raft Source: Ensembl
Keywords - Cellular componenti
Endoplasmic reticulumARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 17 | Sequence analysisAdd BLAST | 17 | |
ChainiPRO_5010815451 | 18 – 417 | Collagen-binding proteinSequence analysisAdd BLAST | 400 |
Interactioni
GO - Molecular functioni
- unfolded protein binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 10036.XP_005074034.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 51 – 408 | SERPINInterPro annotationAdd BLAST | 358 |
Sequence similaritiesi
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | KOG2392, Eukaryota |
OrthoDBi | 1124079at2759 |
Family and domain databases
CDDi | cd02046, hsp47, 1 hit |
Gene3Di | 2.30.39.10, 1 hit 3.30.497.10, 1 hit |
InterProi | View protein in InterPro IPR023795, Serpin_CS IPR023796, Serpin_dom IPR000215, Serpin_fam IPR033830, Serpin_H1_domain IPR036186, Serpin_sf IPR042178, Serpin_sf_1 IPR042185, Serpin_sf_2 IPR033547, SERPINH1 |
PANTHERi | PTHR11461, PTHR11461, 1 hit PTHR11461:SF27, PTHR11461:SF27, 1 hit |
Pfami | View protein in Pfam PF00079, Serpin, 1 hit |
SMARTi | View protein in SMART SM00093, SERPIN, 1 hit |
SUPFAMi | SSF56574, SSF56574, 1 hit |
PROSITEi | View protein in PROSITE PS00284, SERPIN, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A1U7QK99-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRSLLLAFFC LWAVALAAEV KKPVEAAAPG TAEKLSSKAT TLAERSTGLA
60 70 80 90 100
FSLYQAMAKD QAVENILLSP LVVASSLGLV SLGGKATTAS QAKAVLSAEK
110 120 130 140 150
LRDEEVHTGL GELLRSLSNS TARNVTWKLG SRLYGPSSVN FADDFVHSSK
160 170 180 190 200
QHYNCEHSKI NFRDKRSALQ SINEWASQTT DGKLPEVTKD VERTDGALLV
210 220 230 240 250
NAMFFKPHWD EKFHHKMVDN RGFMVTRSYT VGVTMMHRTG LYNYYDDEKE
260 270 280 290 300
KLQILEMPLA HKLSSLIILM PHHVEPLERL EKLLTKEQLK AWMGKMQKKA
310 320 330 340 350
VAISLPKGVV EVTHDLQKHL AGLGLTEAID KNKADLSRMS GKKDLYLASV
360 370 380 390 400
FHATAFEWDT EGNPFDQDIY GREELRSPKL FYADHPFIFL VRDNQSGSLL
410
FIGRLVRPKG DKMRDEL
Sequence databases
RefSeqi | XP_005074034.1, XM_005073977.1 XP_005074035.1, XM_005073978.2 XP_021085165.1, XM_021229506.1 |
Genome annotation databases
GeneIDi | 101829082 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_005074034.1, XM_005073977.1 XP_005074035.1, XM_005073978.2 XP_021085165.1, XM_021229506.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10036.XP_005074034.1 |
Genome annotation databases
GeneIDi | 101829082 |
Organism-specific databases
CTDi | 871 |
Phylogenomic databases
eggNOGi | KOG2392, Eukaryota |
OrthoDBi | 1124079at2759 |
Family and domain databases
CDDi | cd02046, hsp47, 1 hit |
Gene3Di | 2.30.39.10, 1 hit 3.30.497.10, 1 hit |
InterProi | View protein in InterPro IPR023795, Serpin_CS IPR023796, Serpin_dom IPR000215, Serpin_fam IPR033830, Serpin_H1_domain IPR036186, Serpin_sf IPR042178, Serpin_sf_1 IPR042185, Serpin_sf_2 IPR033547, SERPINH1 |
PANTHERi | PTHR11461, PTHR11461, 1 hit PTHR11461:SF27, PTHR11461:SF27, 1 hit |
Pfami | View protein in Pfam PF00079, Serpin, 1 hit |
SMARTi | View protein in SMART SM00093, SERPIN, 1 hit |
SUPFAMi | SSF56574, SSF56574, 1 hit |
PROSITEi | View protein in PROSITE PS00284, SERPIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A1U7QK99_MESAU | |
Accessioni | A0A1U7QK99Primary (citable) accession number: A0A1U7QK99 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2017 |
Last sequence update: | May 10, 2017 | |
Last modified: | February 10, 2021 | |
This is version 21 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |