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Protein

Transporter

Gene

Slc6a18

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Biological processSymportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:Slc6a18Imported
OrganismiMesocricetus auratus (Golden hamster)Imported
Taxonomic identifieri10036 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
Proteomesi
  • UP000189706 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 44HelicalSequence analysisAdd BLAST19
Transmembranei56 – 77HelicalSequence analysisAdd BLAST22
Transmembranei98 – 126HelicalSequence analysisAdd BLAST29
Transmembranei178 – 197HelicalSequence analysisAdd BLAST20
Transmembranei209 – 232HelicalSequence analysisAdd BLAST24
Transmembranei252 – 277HelicalSequence analysisAdd BLAST26
Transmembranei289 – 310HelicalSequence analysisAdd BLAST22
Transmembranei400 – 421HelicalSequence analysisAdd BLAST22
Transmembranei442 – 461HelicalSequence analysisAdd BLAST20
Transmembranei473 – 496HelicalSequence analysisAdd BLAST24
Transmembranei517 – 537HelicalSequence analysisAdd BLAST21
Transmembranei566 – 592HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR000175 Na/ntran_symport
IPR002438 Na/ntran_symport_orphan
IPR037272 SNS_sf
PANTHERiPTHR11616 PTHR11616, 1 hit
PfamiView protein in Pfam
PF00209 SNF, 1 hit
PRINTSiPR00176 NANEUSMPORT
PR01206 ORPHTRNSPORT
SUPFAMiSSF161070 SSF161070, 2 hits
PROSITEiView protein in PROSITE
PS00610 NA_NEUROTRAN_SYMP_1, 1 hit
PS00754 NA_NEUROTRAN_SYMP_2, 1 hit
PS50267 NA_NEUROTRAN_SYMP_3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

A0A1U7Q3E1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQASGIDPL VDMEDDRPKW DNKLQYLLSC IGFAVGLGNI WRFPYLCQTY
60 70 80 90 100
GGGAFLIPYF IALVFEGIPL FYIELAIGQR LRRGSIGVWR TISPYLGGVG
110 120 130 140 150
LGCFSVSFLV SLYYNTVLLW VLWYFLNSFQ YPLPWSTCPL DLNRTGFVRE
160 170 180 190 200
CQSSGTVSYY WYRQTLNISS DIGNTGTIQW KLFLCLVACW ATVYLCVIRG
210 220 230 240 250
IESTGKAIYF TALFPYVVLT IFLVRGLTLP GATEGLTYLF TPNMKILQNP
260 270 280 290 300
RVWLDAATQI FFSLSLAFGG HIAFASYNPP RNNCEKDAVT IALVNSMTSL
310 320 330 340 350
YASITIFSIM GFKATNDYGR CLDRNILSLI NEFDFPELSI SRDEYPEVLM
360 370 380 390 400
YLNATQADRL AQLPLKTCHL EDFLDKSASG PGLAFIVFTE AVLHMPGASV
410 420 430 440 450
WSVLFFGMLF TLGLSSMFGN MESVITPLFD LGILPRSVPK EAMTGMVCLV
460 470 480 490 500
CFISAICFTL QSGSYWLEIF DSFAASLNLI IFAFMEVVGV IYVYGMKRFC
510 520 530 540 550
DDIEWMTGRR PSLYWQVTWK VVSPLLLFSI FLSYIILLSQ TPPSYKAWNP
560 570 580 590 600
QYEHFPSREE KLYPGWVQVT CILMSFLPSL WVPSVALAHL LYQHRRRQKD
610
THLESGLKPQ ESRSC
Length:615
Mass (Da):69,650
Last modified:May 10, 2017 - v1
Checksum:iB40EB00A5CE87742
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1U7Q680A0A1U7Q680_MESAU
Transporter
Slc6a18
552Annotation score:

Sequence databases

RefSeqiXP_005065497.1, XM_005065440.1

Genome annotation databases

EnsembliENSMAUT00000009452; ENSMAUP00000005714; ENSMAUG00000007818
GeneIDi101831631

Similar proteinsi

Entry informationi

Entry nameiA0A1U7Q3E1_MESAU
AccessioniPrimary (citable) accession number: A0A1U7Q3E1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: June 20, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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