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Entry version 12 (02 Dec 2020)
Sequence version 1 (07 Jun 2017)
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Protein

Phospho-N-acetylmuramoyl-pentapeptide-transferase

Gene

mraY

Organism
Rhizobium pusense
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferaseUniRule annotationImportedARBA annotation
Biological processCell cycle, Cell divisionUniRule annotationARBA annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotation, Peptidoglycan synthesisUniRule annotation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
RSP424182:BN877_RS10235-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00219

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferaseUniRule annotationARBA annotation (EC:2.7.8.13UniRule annotationARBA annotation)
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferaseUniRule annotationARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mraYUniRule annotationImported
ORF Names:BN877_I2172Imported, BTE56_19705Imported, CFBP5496_10105Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRhizobium pusenseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri648995 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000016944 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei25 – 48HelicalUniRule annotationAdd BLAST24
Transmembranei69 – 90HelicalUniRule annotationAdd BLAST22
Transmembranei96 – 114HelicalUniRule annotationAdd BLAST19
Transmembranei134 – 154HelicalUniRule annotationAdd BLAST21
Transmembranei174 – 193HelicalUniRule annotationAdd BLAST20
Transmembranei205 – 225HelicalUniRule annotationAdd BLAST21
Transmembranei245 – 262HelicalUniRule annotationAdd BLAST18
Transmembranei269 – 288HelicalUniRule annotationAdd BLAST20
Transmembranei294 – 317HelicalUniRule annotationAdd BLAST24
Transmembranei344 – 363HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyltransferase 4 family. MraY subfamily.UniRule annotationARBA annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_023982_0_0_5

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06852, GT_MraY, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00038, MraY, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR000715, Glycosyl_transferase_4
IPR003524, PNAcMuramoyl-5peptid_Trfase
IPR018480, PNAcMuramoyl-5peptid_Trfase_CS

The PANTHER Classification System

More...
PANTHERi
PTHR22926, PTHR22926, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00953, Glycos_transf_4, 1 hit
PF10555, MraY_sig1, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00445, mraY, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS01347, MRAY_1, 1 hit
PS01348, MRAY_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1S9E852-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLIWLVELSD KIQIFNLFRY ITFRAGAAMF TSALIVFLFG PAIINSLRVR
60 70 80 90 100
QGKGQPIRAD GPQTHFKKAG TPTMGGLMIL AGILGGSLLW GDLSNVYVVA
110 120 130 140 150
VLMVTLGFGA IGFYDDYLKV TKQSDKGFSG KARLGIEFLI AAIAVFFMMK
160 170 180 190 200
MALASAPHGG TLGSSIAFPF FKEFVINLGY FFVLFGAFVI VGAGNAVNLT
210 220 230 240 250
DGLDGLAIVP VMIAAATFGV IAYLAGNAVF ANYLQINFVP GTGELAVIVG
260 270 280 290 300
AVIGAGLGFL WFNAPPAAIF MGDTGSLALG GLIGSIAVAT KHEIVMVIVG
310 320 330 340 350
GLFVMETLSV IIQVFWFKRT GRRVFLMAPI HHHFEKKGWT ESQVVIRFWI
360
ISVGLALLGL ATLKLR
Length:366
Mass (Da):39,141
Last modified:June 7, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i21AB907DD7D7D0F8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HG518322 Genomic DNA Translation: CDI09063.1
MRDJ01000021 Genomic DNA Translation: OOO17453.1
SWKG01000001 Genomic DNA Translation: TKD28468.1

NCBI Reference Sequences

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RefSeqi
WP_003522196.1, NZ_WJOL01000004.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CDI09063; CDI09063; BN877_I2172

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
50491097

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rir:BN877_I2172

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|424182.3.peg.2141

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HG518322 Genomic DNA Translation: CDI09063.1
MRDJ01000021 Genomic DNA Translation: OOO17453.1
SWKG01000001 Genomic DNA Translation: TKD28468.1
RefSeqiWP_003522196.1, NZ_WJOL01000004.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiCDI09063; CDI09063; BN877_I2172
GeneIDi50491097
KEGGirir:BN877_I2172
PATRICifig|424182.3.peg.2141

Phylogenomic databases

HOGENOMiCLU_023982_0_0_5

Enzyme and pathway databases

UniPathwayiUPA00219
BioCyciRSP424182:BN877_RS10235-MONOMER

Family and domain databases

CDDicd06852, GT_MraY, 1 hit
HAMAPiMF_00038, MraY, 1 hit
InterProiView protein in InterPro
IPR000715, Glycosyl_transferase_4
IPR003524, PNAcMuramoyl-5peptid_Trfase
IPR018480, PNAcMuramoyl-5peptid_Trfase_CS
PANTHERiPTHR22926, PTHR22926, 1 hit
PfamiView protein in Pfam
PF00953, Glycos_transf_4, 1 hit
PF10555, MraY_sig1, 1 hit
TIGRFAMsiTIGR00445, mraY, 1 hit
PROSITEiView protein in PROSITE
PS01347, MRAY_1, 1 hit
PS01348, MRAY_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1S9E852_9RHIZ
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1S9E852
Secondary accession number(s): U4PVH9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2017
Last sequence update: June 7, 2017
Last modified: December 2, 2020
This is version 12 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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