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Protein

Cytochrome c oxidase subunit 2

Gene

COII

Organism
Syndemis afflictana
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotationSAAS annotation, Transport
LigandCopperUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 2UniRule annotationSAAS annotation
Gene namesi
Name:COIIImported
Encoded oniMitochondrionImported
OrganismiSyndemis afflictanaImported
Taxonomic identifieri687140 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaTortricoideaTortricidaeTortricinaeSyndemis

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 57HelicalSequence analysisAdd BLAST24
Transmembranei69 – 93HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 97COX2_TMInterPro annotationAdd BLAST91
Domaini98 – 231COX2_CUAInterPro annotationAdd BLAST134

Sequence similaritiesi

Belongs to the cytochrome c oxidase subunit 2 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

CDDicd13912 CcO_II_C, 1 hit
Gene3Di1.10.287.90, 1 hit
2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR002429 CcO_II-like_C
IPR034210 CcO_II_C
IPR001505 Copper_CuA
IPR008972 Cupredoxin
IPR014222 Cyt_c_oxidase_su2
IPR011759 Cyt_c_oxidase_su2_TM_dom
IPR036257 Cyt_c_oxidase_su2_TM_sf
PfamiView protein in Pfam
PF00116 COX2, 1 hit
PF02790 COX2_TM, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
SSF81464 SSF81464, 1 hit
TIGRFAMsiTIGR02866 CoxB, 1 hit
PROSITEiView protein in PROSITE
PS00078 COX2, 1 hit
PS50857 COX2_CUA, 1 hit
PS50999 COX2_TM, 1 hit

Sequencei

Sequence statusi: Fragment.

A0A1S6ENL3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
NILFLEMATW SNFNLQNSAS PLMEQIIFFH DHTLVILIMI TILVGYLMIN
60 70 80 90 100
LFFNSYINRF LLEGQMIELI WTILPAITLI FIALPSLRLL YLLDELNNPL
110 120 130 140 150
ITLKSIGHQW YWSYEYSDFN NIQFDSYMIP INEMKNNNFR LLDVDNRIVL
160 170 180 190 200
PMNNQIRILV TATDVIHSWT IPSLGVKVDA NPGRLNQTNF FINRPGIFYG
210 220 230 240
QCSEICGANH SFMPIVIESI SIKNFINWIN NYSSLDDWKQ VM
Length:242
Mass (Da):28,280
Last modified:May 10, 2017 - v1
Checksum:i866943C1ABCD6E5C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei242Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KY501294 Genomic DNA Translation: AQR59587.1
KY501300 Genomic DNA Translation: AQR59593.1
KY501301 Genomic DNA Translation: AQR59594.1
KY501321 Genomic DNA Translation: AQR59614.1
KY501326 Genomic DNA Translation: AQR59619.1
KY501332 Genomic DNA Translation: AQR59625.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KY501294 Genomic DNA Translation: AQR59587.1
KY501300 Genomic DNA Translation: AQR59593.1
KY501301 Genomic DNA Translation: AQR59594.1
KY501321 Genomic DNA Translation: AQR59614.1
KY501326 Genomic DNA Translation: AQR59619.1
KY501332 Genomic DNA Translation: AQR59625.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd13912 CcO_II_C, 1 hit
Gene3Di1.10.287.90, 1 hit
2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR002429 CcO_II-like_C
IPR034210 CcO_II_C
IPR001505 Copper_CuA
IPR008972 Cupredoxin
IPR014222 Cyt_c_oxidase_su2
IPR011759 Cyt_c_oxidase_su2_TM_dom
IPR036257 Cyt_c_oxidase_su2_TM_sf
PfamiView protein in Pfam
PF00116 COX2, 1 hit
PF02790 COX2_TM, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
SSF81464 SSF81464, 1 hit
TIGRFAMsiTIGR02866 CoxB, 1 hit
PROSITEiView protein in PROSITE
PS00078 COX2, 1 hit
PS50857 COX2_CUA, 1 hit
PS50999 COX2_TM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S6ENL3_9NEOP
AccessioniPrimary (citable) accession number: A0A1S6ENL3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2017
Last sequence update: May 10, 2017
Last modified: March 28, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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