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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnopheles gambiae (African malaria mosquito)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7165 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini22 – 671VitellogeninInterPro annotationAdd BLAST650
Domaini3707 – 3919VWFDInterPro annotationAdd BLAST213

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.20, 1 hit
2.20.50.20, 1 hit
2.30.230.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015819 Lipid_transp_b-sht_shell
IPR001747 Lipid_transpt_N
IPR009454 Lipid_transpt_open_b-sht
IPR011030 Lipovitellin_superhlx_dom
IPR015816 Vitellinogen_b-sht_N
IPR015255 Vitellinogen_open_b-sht
IPR015817 Vitellinogen_open_b-sht_sub1
IPR001846 VWF_type-D

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06448 DUF1081, 1 hit
PF09172 DUF1943, 1 hit
PF01347 Vitellogenin_N, 1 hit
PF00094 VWD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01169 DUF1943, 1 hit
SM00638 LPD_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48431 SSF48431, 1 hit
SSF56968 SSF56968, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51211 VITELLOGENIN, 1 hit
PS51233 VWFD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1S4H025-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DPLRDPQICG RPVCYNSTKF NYNVGHLYKY DHSMYVKTTV VGSSDNTSEL
60 70 80 90 100
HISSIVEVDF HAPCQGILRL HSIEVRERAE RPVEEVEFEY GEEPEDTQPQ
110 120 130 140 150
AVDEQNGMHP KSDVIAEELM RFELRFDFHD GMIGELCHED DEPVWTLNLK
160 170 180 190 200
RGILSALQNT MPRLDIDYDT TETDVSGICD VQYKTNGRNG TGLLFRKTKD
210 220 230 240 250
LASCRRRHKT KSFIQTVSYD FRTNNVVWPI LKSESYCDIM IDNSIYKSVA
260 270 280 290 300
CYERHQLVPF SNGLAGAVTE TYNRLELTDE ETYSQESNNE IDIQRRSSLL
310 320 330 340 350
YDHTPSVHES HDEIKASREL LIELCVHGFP NIKREFPTVF LKFLTTARAL
360 370 380 390 400
SSNALKQLLM RSRSICDNGQ KHILESLPYI GSAASVTLMK DQIVENNVEP
410 420 430 440 450
ALANKWMESF AFLTRPNEEV LEAMLELMKH GKESGDQTYL LSATTVVNTF
460 470 480 490 500
CKIHFDCDES EEVQAIVQYL EEELLDTIES VEVMAENDRQ KRERVIVLLM
510 520 530 540 550
SLGNMGVINK RLNFELRAII ESERYPIEIR VEAVNVFRRS DCTRTKDYFL
560 570 580 590 600
KLYSTFLLDV EVRIAAYLQA MRCPDHLSVR LIKNVLKTEE VKQVGSFVWS
610 620 630 640 650
HLTNLAKSAS PVRVQAQGLL AENDLDSKFN LDVRKFSRNY EQTLFFDEYN
660 670 680 690 700
FGMTVDSNVI FSTESYVPRS VRLNLTTDLF GESINFLELN VRLEGLEQSV
710 720 730 740 750
HHLFGPNGTY SAKKVGERVD TYMKFLRQYV PTKVLELFDG ESSWRDYLQD
760 770 780 790 800
PDESGRQKRA AVERLPQVIA RQIQEDVDRL GFQLKGNFDK PQVTIGVKIF
810 820 830 840 850
GNDLHYYSNG LELLKISDER KKLANLFSGK ESSYTKSSVF LDTSYDVPLS
860 870 880 890 900
SGMPLALGLV GASSLDFHSM GNIKAFDFTR WLIDIEGKLK PSITMDITAS
910 920 930 940 950
MRSDLMHAST AIIVKTNLYS SSTLAAHLKL RGTDQAVLQV SLPQERNDIF
960 970 980 990 1000
SIRSEMFVLT ERRELQQAGI ERRYSNSTCT WPYINQAIGL KMCTNYSLPD
1010 1020 1030 1040 1050
VSNTGKDVKV PSLILSGPVN FDVSLEKADP TAKMFVLKYS WAERQNQTIV
1060 1070 1080 1090 1100
GVVFETPNSQ IPRIFRANIT NEVQRKTASM SFVNGNISHK AIGLYINNPN
1110 1120 1130 1140 1150
QLQVEMSLNV NDRKYLALEL HLNKTDTRNG RMYYPSFYLS VNHERIAGLG
1160 1170 1180 1190 1200
GQIKYTERKN ISQWEYIVMI ETRRVRATAT GYVSVSHNMT YMIHNTVEYR
1210 1220 1230 1240 1250
VRSNPEQLVI NALAEIVQQE ALTYRANFDL RSSAYPHFDV ALNASLLDRM
1260 1270 1280 1290 1300
GLLDFTLLHN NAPDLRDEKF RTTLNVIFAR EGPYQGQQLI GGSTVQTDPT
1310 1320 1330 1340 1350
ERATVSVELT RPRANIDVKA MIVYDNMPRK GVYRTVRMLL RYAAAKEIVG
1360 1370 1380 1390 1400
IFSIVMPRSQ RFWLESVFNM TVPGVHPCMA TIRLIETSTK EHRFDFQGIW
1410 1420 1430 1440 1450
FTEHAANITG LYKDRSSSAK FHHHAKLAAQ FGRPNSIREF FGDMKYVQDE
1460 1470 1480 1490 1500
FDHRLSINAM FEKKPYGIIL QHTQQIANGT KSYAMVQWKD ERYWFSALMK
1510 1520 1530 1540 1550
SAAIKQLDLE LHIDKIRDIS ATLRGYKTPL KREVGVEFKW DANRDPTQRI
1560 1570 1580 1590 1600
ALTGELNTPT DRIYDGLFLL SYPNRTFSGT FDLKAIHPRY LANARISWNT
1610 1620 1630 1640 1650
TEAIVIHFDA GTHEEMLSKM WLLLHLNTTF HGWRRNALSG AFSFKDNVLY
1660 1670 1680 1690 1700
TDLIANWAED QRLGVELNGT YRSNKEIFNC ELGTQLKSSL RNIPAVTMYF
1710 1720 1730 1740 1750
NQTLVTDRVE TTVLLNYETT DQPVQEFSVR SNWQHKADKR HSNITGSLRL
1760 1770 1780 1790 1800
ISPYENYRMG ALVAKVSVSE NRTITGAADL QLDDNTYDLL LEGHIRNLVD
1810 1820 1830 1840 1850
CMLTANITSS NINYRSINGR FGISEKNRHL VAEIITPKTE LGIELLYAVV
1860 1870 1880 1890 1900
SPQNFDVKFH LATPLKELEK VILRAKLQKD NVDFRAGMNN MVLGCTGVWR
1910 1920 1930 1940 1950
KAHLKDFEYS YRIYTPLQKF EESALIVKVV INSERAQYVD VELSGKFSEY
1960 1970 1980 1990 2000
KLGVKAMSKP KPDIKRVMLP QTASSLVEEN LWNNEVDDEQ DDEDYDEEED
2010 2020 2030 2040 2050
EENLLNFIGE IELYTIVMPT IEGTLELTEQ NSQYRAIGKL KVPQGDIDFR
2060 2070 2080 2090 2100
DRFYLRHLLN MHNSLQLKTP FPVAQQITSE FVMKFSDETT DITVGMNVKF
2110 2120 2130 2140 2150
NNRSEWVNTG FHVNYKKSVD EAEVHKHQAL VDLMTPMKNL QKVFLNGTLE
2160 2170 2180 2190 2200
LEDHSYKGNL TAKTMTTDAS LALSFEAEDQ FIDTFMSVWV RAPLMPYYAC
2210 2220 2230 2240 2250
RVFYKQDYSS TENSMDLGFT VNDGDLYSNF RMDGAWSFAK PHYIKGAGKY
2260 2270 2280 2290 2300
QSNFLPINLI NTDFLITRSP LPRAYWNVKF HDKNGVVEEI KARAERNREL
2310 2320 2330 2340 2350
FMIDLSVPME DYRNFSIHGR LQHRQGSEYA VSGQLYRNEH IFQVEGSATI
2360 2370 2380 2390 2400
AEDIPYRAEL AFQPLTPEGS IGSIRYDCRN SSTSTEFNLE VESGNKVAKL
2410 2420 2430 2440 2450
DGSFKLLAMS DWFLKLGLES SEPGLKSVDF YMGINPEANG KALGKFNLHS
2460 2470 2480 2490 2500
PWVQYGIDQA DVEMMFDVQP ISGSVMARYG IRDVSGNASC LWNWALKSNT
2510 2520 2530 2540 2550
QFALENRVLR NSVERYFRTG VRYVSPDLEN NHNLTFGGDL NLNNIWIFSA
2560 2570 2580 2590 2600
NSSVDFISIR DMSAVLKVLL PKPVGDVHTL ALAMNGNLPF LEPVKSFNME
2610 2620 2630 2640 2650
TSYETDESRK RYAYHSEYSG IGDIRALVRF DWGPDVRKER IQSILNVFRI
2660 2670 2680 2690 2700
GDRQELMVTL RGPWYLEDAF VTHGTYDTIE NLYLVSGNIS MPASTKVMSA
2710 2720 2730 2740 2750
NVEFNNLSNM KADVNCTTPF LNVSWIHGQL EFIESPIESI RYVKGSWPES
2760 2770 2780 2790 2800
SAIFDAKATY RNNNQDREQQ GTVKMEVPLQ TRHFAEIKYG LSERPAITTG
2810 2820 2830 2840 2850
YAEVEYNSKN VLSGQYTSKE ESRPGFDKET IEAMLKNEYK PIGVHYVHSV
2860 2870 2880 2890 2900
NKQDPTVESM DFKRAEIFEL DNKEDNKFNV TGELHVLSKE KGHEYIVRAI
2910 2920 2930 2940 2950
QTNRTVELTA NIEEDNIVSK KQSRLQLAPT VWIAYDFERT NRSRDDVEAQ
2960 2970 2980 2990 3000
NFTLKISYPN RNISADGWYS YTSSAFDSDI TLSYSPNRTN AEDESEMPKQ
3010 3020 3030 3040 3050
RTVRGGVVWR DLANRSTDGQ QIRVFLGHPS FQRDVTVDAR YFTDPKHWFS
3060 3070 3080 3090 3100
SKAELRYNDD NEHLLAMGLD LNDMQPIVGF WNYSYHLFST HEASDLDLDS
3110 3120 3130 3140 3150
IGSIGLRPGL WGVSSNSHYK RAYLSQMHGH VLGWMNLHQK EMHYERITSQ
3160 3170 3180 3190 3200
SKYRIWTKAT GAYPVYLING TLLDGPELDA TGFFYLNIDD KMVQMKINMT
3210 3220 3230 3240 3250
PDGSENVYMY GIIPDTRSAY FDLWRDYDKA REVDVTYYLK MNHSRLITGH
3260 3270 3280 3290 3300
LLWRPEIKSD VQKLVRDYVN QIHQSFMESI EFWIKQVYLE TKDSTMSIYE
3310 3320 3330 3340 3350
AAVPYIEEFL EDANGLSILQ HDLEELHQFF NASYYVDDFY IRSIANITMT
3360 3370 3380 3390 3400
MLNELALKNK ETSYPTILAE LLQVMGESGK SLGKSVILAL EQVKQSYEKF
3410 3420 3430 3440 3450
MHMIFSTFDG SAVQYLSYLV EDSIKQFDKF VKEAHVEFVK QTDSLWERTV
3460 3470 3480 3490 3500
IMTKTLWKGL LQNIEPTIVQ LLNYGESLDW FAGNELLTFL HNTTQEIAES
3510 3520 3530 3540 3550
PHFNTIINFT NDVELLYRDL TTNDLWSNLQ KYSSVLWEFL HQKYFQLIPF
3560 3570 3580 3590 3600
AEDLNLAWIK LLEEVKQLRK IDFVHYFIQR YEEVQAYAIR LAEEFEHRYH
3610 3620 3630 3640 3650
LTQVFRLIGR KLLYLEQTAL EAEDHYRKAK TKFIFDPDRG VIELEQKLPM
3660 3670 3680 3690 3700
SWHAFNETPK FEEIPEFKYI SKIQDLFAGS NTTIWTVYND ICPYVDLEVW
3710 3720 3730 3740 3750
LPPFKSTALL IGSRHYMSFD KRFVSLDLND SNHCQYLLAH DYYNRTITLL
3760 3770 3780 3790 3800
LESSDLRYGQ TSRQITLIID DNTLAIDVFN ISVKINNKAT ALPAMIGTQT
3810 3820 3830 3840 3850
VVFQQSDQLW IQSQRGFLIG CSLRYHICWL ELSGWYFGKM AGLLGTMNNE
3860 3870 3880 3890 3900
MFDDRITSTN RYNETEEQFL NSWALPGCSS TVTGTNHTSN FYSASNELSQ
3910 3920 3930 3940 3950
LCDSFFHQKL SYLATCFSVV DVTPFYEMCM DLGHNLMPDR GACTAAIAYI
3960 3970 3980 3990 4000
QACSLERTPL RVPNNCISCL LMNGSYVPEG SFVPLRNEEV PKAADVVFII
4010 4020 4030 4040 4050
EAKPCNERFV ETKSINLLVS GIARELQDLG IDDTLFGVVT FGGSAPFDRA
4060 4070 4080 4090 4100
HSVVVGNSVF EMHNGTQPFF DHVKIGNGTN EDIFDAITMA SNLVFRPGAS
4110 4120 4130 4140 4150
KTFVLLPCSR CVASKMKLDF SSIVQLLVEN DIKLHILADQ ELSFQKSRVS
4160 4170 4180 4190 4200
RLFYGMDSQM VYTKKDVKEL IGDAELRRQI QLPKATLGEC IALAMETNGS
4210 4220 4230 4240 4250
IFGGHKLRQD RSNTANTKKF IKVFAKRIAA SALPNSCQTC ECTGHNTGVA
4260 4270 4280
YMQCTPCNYP SPFSMEDGNM TDDMLLSVMQ PDGEWDDGF
Length:4,289
Mass (Da):491,784
Last modified:April 12, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD3AAFFCA47073653
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAAB01008944 Genomic DNA No translation available.

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
AGAP008810-RA; AGAP008810-PA; AGAP008810

Bioinformatics Resource for Invertebrate Vectors of Human Pathogens

More...
VectorBasei
AGAP008810-RA; AGAP008810-PA; AGAP008810

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008944 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAGAP008810-RA; AGAP008810-PA; AGAP008810
VectorBaseiAGAP008810-RA; AGAP008810-PA; AGAP008810

Family and domain databases

Gene3Di1.25.10.20, 1 hit
2.20.50.20, 1 hit
2.30.230.10, 1 hit
InterProiView protein in InterPro
IPR015819 Lipid_transp_b-sht_shell
IPR001747 Lipid_transpt_N
IPR009454 Lipid_transpt_open_b-sht
IPR011030 Lipovitellin_superhlx_dom
IPR015816 Vitellinogen_b-sht_N
IPR015255 Vitellinogen_open_b-sht
IPR015817 Vitellinogen_open_b-sht_sub1
IPR001846 VWF_type-D
PfamiView protein in Pfam
PF06448 DUF1081, 1 hit
PF09172 DUF1943, 1 hit
PF01347 Vitellogenin_N, 1 hit
PF00094 VWD, 1 hit
SMARTiView protein in SMART
SM01169 DUF1943, 1 hit
SM00638 LPD_N, 1 hit
SUPFAMiSSF48431 SSF48431, 1 hit
SSF56968 SSF56968, 2 hits
PROSITEiView protein in PROSITE
PS51211 VITELLOGENIN, 1 hit
PS51233 VWFD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1S4H025_ANOGA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1S4H025
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: November 7, 2018
This is version 11 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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