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Protein
Submitted name:

Myosin XV

Gene

1274922

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi203 – 210ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin XVImported
Gene namesi
Name:1274922Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 797Myosin motorInterPro annotationAdd BLAST686
Domaini969 – 1120MyTH4InterPro annotationAdd BLAST152
Domaini2568 – 2722MyTH4InterPro annotationAdd BLAST155
Domaini2727 – 3046FERMInterPro annotationAdd BLAST320

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni673 – 695Actin-bindingPROSITE-ProRule annotationAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili514 – 534Sequence analysisAdd BLAST21
Coiled coili870 – 890Sequence analysisAdd BLAST21
Coiled coili2089 – 2109Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
cd01387 MYSc_Myo15, 1 hit
Gene3Di1.25.40.530, 2 hits
2.30.29.30, 2 hits
3.40.850.10, 3 hits
InterProiView protein in InterPro
IPR019749 Band_41_domain
IPR035963 FERM_2
IPR019748 FERM_central
IPR000299 FERM_domain
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR035487 MYO15A
IPR001609 Myosin_head_motor_dom
IPR036057 MYSc_Myo15
IPR000857 MyTH4_dom
IPR038185 MyTH4_dom_sf
IPR027417 P-loop_NTPase
IPR011993 PH-like_dom_sf
PANTHERiPTHR13140:SF379 PTHR13140:SF379, 1 hit
PfamiView protein in Pfam
PF00373 FERM_M, 1 hit
PF00612 IQ, 2 hits
PF00063 Myosin_head, 1 hit
PF00784 MyTH4, 2 hits
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00295 B41, 1 hit
SM00015 IQ, 3 hits
SM00242 MYSc, 1 hit
SM00139 MyTH4, 2 hits
SUPFAMiSSF47031 SSF47031, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50057 FERM_3, 1 hit
PS50096 IQ, 3 hits
PS51456 MYOSIN_MOTOR, 1 hit
PS51016 MYTH4, 2 hits

Sequencei

Sequence statusi: Complete.

A0A1S4GNJ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDWSTGDLVW FDPGLGHPLP GEIQEVHRAA QMIIVQALIN GKRIKRRQRR
60 70 80 90 100
METVSELSPS EGKESFVRQQ PARIRRPPRN KLLPDDVPPN PQTFTLGPNE
110 120 130 140 150
GNIRARQDLG KTGVEDMTQL EDLHEASLLW NLKLRYDNGL IYTNAGSILI
160 170 180 190 200
AINPYKMFPE SYGIEMAKLY SGRPLGTLPP HLFAIGSAAH AALPSPQVVV
210 220 230 240 250
ISGESGSGKT ESTKLVMQYL AAVVPGGGSA STVITEQILE AAPLLEAFGN
260 270 280 290 300
ARTVRNDNSS RFGKYLEVYF KSGAIIGAKI TQYLLEKSRI VTQAAGERNY
310 320 330 340 350
HVFYELLGGL AEPERMKYGL LEADKYFYLN QGGSDCAPGR MDWASLQSAM
360 370 380 390 400
QVLGVTESER EGIVKVLASV LHLGNVYFHR RQLRHGQEGV EIGSDAEIKW
410 420 430 440 450
AAHLLQLPSE GILKSLTSRI TETRSERLYT PLGIDQALDA RDALAKALYS
460 470 480 490 500
GLFNWLVLRI NSIVHRGGTH DAQRLSILDI FGFEDLAENS FEQLCINYAN
510 520 530 540 550
ESLQLYFNKH VFKLEQAEYA RERLEWTNLE WEDNLPVIHL LAKKPVGIFH
560 570 580 590 600
LLDDESNFPR ANDSSFLEKC HYNHALNELY SRPRVGAQEF GITHYAGQVW
610 620 630 640 650
YCVDGFLEKN RDALRMDVIE LLSSSTEPLV GEMTKQLRAQ RDVGKTLPKG
660 670 680 690 700
SNGRFVTMKP RTPTVAARFS DSLQQLLQSM AKCNPWFVRC VKPNNDKQAL
710 720 730 740 750
RMDMPCVLQQ LRYLGMLDTI KIRQSGYPVR LRFQHFVERY RHLMRTPLPK
760 770 780 790 800
GTPYRELCRF VLDELPGTTT EGPDFQLGAT RVFLREALHR TLEASRADRL
810 820 830 840 850
RLAAVTIQRT VRGMLARKKV QREVRGAVTI QRYWRGYRDR NRYLTIKNGV
860 870 880 890 900
VKYQALYKGH MQRKRYAKLK NELKRRREAE RLKKERTAQR LAKEQVERGS
910 920 930 940 950
AVPLDIPAEL AFIFSKSENW SGQQSDRNLV KVVGTVPGPP SAADLPPDLD
960 970 980 990 1000
QFAFGKFSSV YCNGVKLAPR RDIISAPFLS RAAARDQDFK DAIAIFKLII
1010 1020 1030 1040 1050
RWTTDATMDA NREKILADYI VHKGLSSRGL RDEILVQICN QVYRADEAAA
1060 1070 1080 1090 1100
EKLWTLMSHC LSAFQPGSAF SKYLIKFIVD NAPPNTKEQI LKKLLRNANA
1110 1120 1130 1140 1150
GQTNPCRLFP PAWLEWRASS RLADTALGLN LPDNSVQTVA VDSWTTCEEA
1160 1170 1180 1190 1200
AALAISSFGI PNLGWTVVID ESDQMTDSCG LDFVLDLVAE KELPPAFPAV
1210 1220 1230 1240 1250
RSDILRCGRK GGAPSAAPGT HDSSAEPSSP KRPQVPPPEP PSMKRSSHEI
1260 1270 1280 1290 1300
QLVPVAIGSG TKKHEPAEYG GGGGAASRHH MEPSSAGRKT SHDVSLSRHK
1310 1320 1330 1340 1350
LREERAFYED KSRSRSLDDL LAGEADDALL APDADEPETS LTLTLAENRI
1360 1370 1380 1390 1400
GNKYRSVDTI APLKEQHPRF VKSQYAGKRS SGSHSLKYAE KSEFSVRSSA
1410 1420 1430 1440 1450
MSDTSEAPSL ASHVRRVRVP SQASDVDQFL DDLFSPVLDG SLDELSDARS
1460 1470 1480 1490 1500
LAASIRGGAQ FVSELLATVR TDRSLTDLEQ SAVLASATQG GTTHQAKNAT
1510 1520 1530 1540 1550
SNGFTPSAPN PIAPLSPPVS SSGSLLMMGS VSPDVVMPVF TIPPGVDSTA
1560 1570 1580 1590 1600
YQQQMQRAFL QSAMAQNIQI QQQLMAQNQA LQTLLTQQDG AGPSSSSSPA
1610 1620 1630 1640 1650
NPGAASPKHG GATGSPTSVQ HSPIRKMSAK AGGRNDSTDR PIGPPATSTS
1660 1670 1680 1690 1700
FSDMLRNRKD SSSSNLIPPP PPPPLPPPLE LKDPFEVRPF LDPYGRAKTV
1710 1720 1730 1740 1750
RIGKWRWPPP QGVTASTETE ETFIQFKMTR QSNRKTTPQS QHSSSNLDSP
1760 1770 1780 1790 1800
IGSPNGVEWE EFEIDQKLQE QAAREADAGG KGAGGGGQQP GGAARTAKRS
1810 1820 1830 1840 1850
FDIGADRPAP NSVGKLKLSN EMRQRLEQVT AGHSVRSSSA KSDRPERTPA
1860 1870 1880 1890 1900
KLEDTRRMML EQQLGGMNPP GGAKSPGGDA VPSVKTQVQR MEASKKGAPA
1910 1920 1930 1940 1950
TAWPTVSVLP PAPPGPAPPP PIRPPTSTPP APPPPIHGNM MAAQNAHQQN
1960 1970 1980 1990 2000
QSEIPSFVQR QERDTFGAKD SFMDSWGRAE AAKLDLVYET SFKKEMIIER
2010 2020 2030 2040 2050
ERSRSRSRSR DRENFSESVW DRSEVEGPSS TSSDPRDRDR GDKEREARER
2060 2070 2080 2090 2100
NYELTQLQRE KESNKVFHPS SYTKDKQQQQ HHQQHHQQHQ QQQQQQSQYQ
2110 2120 2130 2140 2150
QQYQQQQKQY SANAPGSGIA TFKTHMVQKS VQERERKSSA ATTNGSVYSE
2160 2170 2180 2190 2200
KLDDGAMADP PAPVLPVQMN PSLKAPAAAC LTYNRVTWTL RVRKEVFRPS
2210 2220 2230 2240 2250
ETVTAPAALD LLFNQITADV FGVTPCMRIS PQEKRLAVNL LSSHGITANG
2260 2270 2280 2290 2300
HSTAKQHVRA IVKRHVLDMA RGWPLYFARL FVMNGSPSIQ EGTLLAVSHM
2310 2320 2330 2340 2350
GVYLASKEPE FLSIQRAIPF DDIQSVTTLP RPLTLQLTLK TGARLVMHAS
2360 2370 2380 2390 2400
KANAIQVMVQ SYLAEYRQTQ SKGSTISSGV RAAAATLNVP LERLETSNVN
2410 2420 2430 2440 2450
SPGSPNQMSP TDKGHHLHHM MGGHPGQHQS PHHLHHLHHQ QQQQLMDEFE
2460 2470 2480 2490 2500
DMHIDHGGLA DSSPPPTMMG GPTDGGMAGR AGSGGGTGSG MIVNHKGSPM
2510 2520 2530 2540 2550
GNGNGNYSDM HIVAGGHHEN DSSPTQTSLT KHSLLQFAMQ HFRTDDEFKS
2560 2570 2580 2590 2600
NRSDKRAMRN QHADLVKWQG YPLRAPLLRL PADLTPLALE CFDCVLRYCG
2610 2620 2630 2640 2650
DLAVDPELSE VKCVYTVLMH CHKHLALRDE VYCQLMKQTT ANRSACPDSA
2660 2670 2680 2690 2700
QRAWRLLSIL AAYFGCSDAL RPYLIEHLTS AASDRRRPCH GTAAVCLTNL
2710 2720 2730 2740 2750
RKTARCGGRK NVPSVEEVTA VSAGRSARRQ IYRLPGGAER IVNTRCSTVV
2760 2770 2780 2790 2800
GDVIAELCSL LGIESPAEQQ EFSLYCIVQG DAFTMPLAAD EYILDVTTEL
2810 2820 2830 2840 2850
LKSGQPFYLI FCRSVWHFAL KRDPAPTPLY IEVLFNQVAP DYLEGLLLEL
2860 2870 2880 2890 2900
PNGGAPSPDY VRDMARIAAI LHRAADLNHL PAMKEIKFLL PKPALSLREL
2910 2920 2930 2940 2950
RPAQWVALVQ SAWPSVAGLS PIQVKAQFLN VLSSWPLFGS SFFAVKRVWA
2960 2970 2980 2990 3000
DENPMEEPSP MWRELILALN RRGVLFLDPN THETMQHWPF NEVISTRKVR
3010 3020 3030 3040 3050
SEDGALFLDM KVGNLLQQRV IRVQTEQAHE ISRLVRQYIT MAQAQQRDRR

E
Length:3,051
Mass (Da):338,023
Last modified:April 12, 2017 - v1
Checksum:i184F8057B6807BA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008900 Genomic DNA No translation available.

Genome annotation databases

EnsemblMetazoaiAGAP005213-RD; AGAP005213-PD; AGAP005213
VectorBaseiAGAP005213-RD; AGAP005213-PD; AGAP005213

Similar proteinsi

Entry informationi

Entry nameiA0A1S4GNJ0_ANOGA
AccessioniPrimary (citable) accession number: A0A1S4GNJ0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: June 20, 2018
This is version 13 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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