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Protein

Condensin complex subunit 1

Gene

NCAPD2

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.UniRule annotation

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, DNA condensationUniRule annotation, MitosisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Condensin complex subunit 1UniRule annotation
Gene namesi
Name:NCAPD2Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 238Cnd1_NInterPro annotationAdd BLAST163
Domaini1064 – 1224Cnd1InterPro annotationAdd BLAST161

Sequence similaritiesi

Belongs to the CND1 (condensin subunit 1) family.UniRule annotation

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR026971 CND1/NCAPD3
IPR032682 Cnd1_C
IPR007673 Condensin_cplx_su1
IPR024324 Condensin_cplx_su1_N
PANTHERiPTHR14222 PTHR14222, 1 hit
PTHR14222:SF2 PTHR14222:SF2, 1 hit
PfamiView protein in Pfam
PF12717 Cnd1, 1 hit
PF12922 Cnd1_N, 1 hit
PIRSFiPIRSF017127 Condensin_D2, 1 hit
SUPFAMiSSF48371 SSF48371, 6 hits

Sequencei

Sequence statusi: Complete.

A0A1S3WHJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPQLFEFHL PLSPAELLKN GGRNKYVVQE VLSIRHLPTQ LRAFQAAFRA
60 70 80 90 100
QGPLAILEHF DTIYSILHHF RSIDSDLKEE TLEFLIKVVS RHSQELPGVL
110 120 130 140 150
DDATLSMSDR SAHLNALKMN CYALIRLLES FETMSSQIMD LELGGKGKKS
160 170 180 190 200
RAKAAHGFDW EEERQPILQL LMQLLQLDIR HLWNHSIIEE EFVSLVTGCC
210 220 230 240 250
YRLLENPTIN HQKNRPTREA IAHLLGVALT RYNHLLSATV KITQMLQHYE
260 270 280 290 300
HLAPVLVAAV SLWATDFGMK SIVGEIVREI GQKCPQELSR DPAGTKGFAA
310 320 330 340 350
FLTELAERIP AVLMSSMCIL LDHLDGENYM MRNAVLAAMA EMILQVLNGD
360 370 380 390 400
QLEEAARDTR DQFLDTLQAH GHDVNSFVRS RVLQLFTRIV QQKVLPLTRF
410 420 430 440 450
QAVVALAVGR LEDKSVLVCK NAIQLLASFL TNNPFSSKLS DTDLAGPLQK
460 470 480 490 500
ETQKLQDMRA QRRATTTSAE LDPEEEWEAM LPELKSTLQQ LLALPQDEEE
510 520 530 540 550
PSLEIAEKET IEDMKGRIHQ LLAKAKYKQA IALTQQTISR FPESEPFSNV
560 570 580 590 600
VPEEPEETKF LSLLETIFKG PAATTQEKNP PTSAGSKGPG LSECKDKPSL
610 620 630 640 650
PGRSRDDEEL VKQEMLVQYL QDAYSFSVKI TQAISIINKM MYENTTSVVQ
660 670 680 690 700
EVIEFFVMVS QFGLPQALHG VRRMLPLIWS KEPGVREAVL NAYRQLYLSP
710 720 730 740 750
KGDSARAKAQ TLIQNLSLLL VNASVGTVQC LEEILCEFVQ KDELKPAVTQ
760 770 780 790 800
VLWERATGKV PCSPLERCSS VMLLGMMARG KPEIVGSNLD LLVDIGLEKR
810 820 830 840 850
CPQDYRLAQQ VCQAITSISD RRKQPSLGKS QPPFRLPQEH RLFERLQDVV
860 870 880 890 900
TQGFVHPDPL WIPFKEVAVA LIYQLAEGPE LICAQMLQSC AKQALDKLEK
910 920 930 940 950
SSTQQDQKEA RVLTLLLMNL LALAGDVALQ QMVHLEQAVS GELCRRRVLR
960 970 980 990 1000
EEQEQKTKEP KEKNTGSETT MEEEMGLVGA TADDTEAELI RGICEMELLD
1010 1020 1030 1040 1050
GKQTLAAFVP LVLKVCNNPG LYNSPELSAA ASLALGKFCM ISATFCDSQL
1060 1070 1080 1090 1100
RLLFTMLEKS SLPIVRSNLM IATGDLAIRF PNLVDPWTPH LYARLRDPAQ
1110 1120 1130 1140 1150
QVRKTAGLVM TQLILKDMVK VKGQVSEMAV LLIDPVSEIS ALAKTFFTEL
1160 1170 1180 1190 1200
SHKGNTIYNL LPDIISRLSD PEGGVEEEPF HTIMKQLLSY ITKDKQTESL
1210 1220 1230 1240 1250
VEKLCQRFRT ARTERQYRDL AYCVSQLPLT ERGLRKMLDN FDCFGDKLSD
1260 1270 1280 1290 1300
ESVFSAFLSV VSKLRRGAKP EGKAMIDEFE QKLRTCHTRG LDAVEELEAG
1310 1320 1330 1340 1350
QGDSQKALST KKQPAASRRQ QQRLASAASS DNDFVTPEPC RRTSRRPLNT
1360 1370 1380 1390
LQRLSKKKPK IVFSSDESSE EDLSAEMTED ETPKKTTPIR RVSARRLRS
Length:1,399
Mass (Da):157,098
Last modified:April 12, 2017 - v1
Checksum:i2720CAF9B0EB640B
GO

Sequence databases

RefSeqiXP_016045762.1, XM_016190276.1

Genome annotation databases

GeneIDi103117726

Similar proteinsi

Entry informationi

Entry nameiA0A1S3WHJ6_ERIEU
AccessioniPrimary (citable) accession number: A0A1S3WHJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: February 28, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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