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Protein
Submitted name:

hepatocyte nuclear factor 1-alpha isoform X1

Gene

HNF1A

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi191 – 271HomeoboxPROSITE-ProRule annotationAdd BLAST81

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
hepatocyte nuclear factor 1-alpha isoform X1Imported
Gene namesi
Name:HNF1AImported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini189 – 270HomeoboxInterPro annotationAdd BLAST82

Keywords - Domaini

HomeoboxPROSITE-ProRule annotation

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR039066 HNF-1
IPR006899 HNF-1_N
IPR023219 HNF1_dimer_N_dom_sf
IPR006898 HNF1a_C
IPR006897 HNF1b_C
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
PANTHERiPTHR11568 PTHR11568, 1 hit
PfamiView protein in Pfam
PF04814 HNF-1_N, 1 hit
PF04813 HNF-1A_C, 1 hit
PF04812 HNF-1B_C, 1 hit
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF100957 SSF100957, 1 hit
SSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS50071 HOMEOBOX_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A1S3WE68-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVARLSQLQA ELLGALLESG LSKEALIQAL GEPGPCLLGA DGHLDKGEPA
60 70 80 90 100
ELPNGLGEPR GSEEETDDDG EDFAPPILKE LENLSPEEAA HQKAVVETLL
110 120 130 140 150
QEDPWRVAKM VKSYLQQHNI PQREVVDTTG LNQSHLSQHL NKGTPMKTQK
160 170 180 190 200
RAALYTWYVR KQREVAQQFT HAGQGGLVEE PTGDELPTKK GRRNRFKWGP
210 220 230 240 250
ASQQILFQAY ERQKNPSKEE REALVEECNR AECIQRGVSP SQAQGLGSNL
260 270 280 290 300
VTEVRVYNWF ANRRKEEAFR HKLAMDTYSG PPPGPGPGSA LPGHSSPGLA
310 320 330 340 350
PPALSPGKVH GVRYGQPTTS EGADGPSGSG GPLVTVSASL HQVSPTGLEP
360 370 380 390 400
SHSLLSTEAK LLGFPSKVSA TGGPLPPVST LTALHSLEQT SPGLNQQPQN
410 420 430 440 450
LIMASLPGVM AIGPGEPASL GPTFTNTGAS TLVIGLATTQ AQSVPVINSM
460 470 480 490 500
GSSLTTLQPV QFSQPLHPSY QQPLMSPVQS HVTQSPFMAT MAQLQSPHAL
510 520 530 540 550
YSHKPEVAQY THTGLLPQTM LIADTSNLGA LASLTPKQVF TSEAEASSES
560 570 580 590 600
GLPTPVSQAT TIHIPNQDPG GIQHLQPHRL SASPSVSSSS LVLYQSSDST
610 620
NGHSHLLPSS HSVIETFIST QMASSSQ
Length:627
Mass (Da):66,655
Last modified:April 12, 2017 - v1
Checksum:i274681D85FBFB1CD
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1S2ZVP4A0A1S2ZVP4_ERIEU
hepatocyte nuclear factor 1-alpha i...
HNF1A
621Annotation score:
A0A1S3WEG7A0A1S3WEG7_ERIEU
hepatocyte nuclear factor 1-alpha i...
HNF1A
628Annotation score:

Sequence databases

RefSeqiXP_016044676.1, XM_016189190.1

Genome annotation databases

GeneIDi103115507

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_016044676.1, XM_016189190.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103115507

Organism-specific databases

CTDi6927

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR039066 HNF-1
IPR006899 HNF-1_N
IPR023219 HNF1_dimer_N_dom_sf
IPR006898 HNF1a_C
IPR006897 HNF1b_C
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
PANTHERiPTHR11568 PTHR11568, 1 hit
PfamiView protein in Pfam
PF04814 HNF-1_N, 1 hit
PF04813 HNF-1A_C, 1 hit
PF04812 HNF-1B_C, 1 hit
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF100957 SSF100957, 1 hit
SSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS50071 HOMEOBOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S3WE68_ERIEU
AccessioniPrimary (citable) accession number: A0A1S3WE68
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: September 12, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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