Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

nuclear receptor subfamily 4 group A member 1 isoform X1

Gene

NR4A1

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi264 – 339Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
nuclear receptor subfamily 4 group A member 1 isoform X1Imported
Gene namesi
Name:NR4A1Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini264 – 339Nuclear receptorInterPro annotationAdd BLAST76
Domaini360 – 596NR LBDInterPro annotationAdd BLAST237

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR003071 Nuc_orp_HMR_rcpt
IPR003070 Nuc_orph_rcpt
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01285 HMRNUCRECPTR
PR01284 NUCLEARECPTR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A1S3W4X5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPCIQAQYGT PAPSPGPRDH LAGDPLTPEL NKPTMDLASP EAAPTAPTVL
60 70 80 90 100
PSFSTFMDGY SGEFDTFLYQ LPGTAQPSSS ASSSASSTSS SSATSPASAS
110 120 130 140 150
FKFEDFQVYG CYPGTLSGPL DETLSSSGSD YYGSPCSVPS PSTPSFQPPQ
160 170 180 190 200
LSPWDSAFGP FSPSQTFEGL RAWTEQLPKA SAPPQPSAFF SFSPPTGLSP
210 220 230 240 250
SLAHSPLKLF SAQAPHQLGE GESYSVPAAF PGLGPTSPLL DGSRMLDAPM
260 270 280 290 300
SSAKARSGAL AGSEGRCAVC GDNASCQHYG VRTCEGCKGF FKRTVQKNAK
310 320 330 340 350
YICLANKDCP VDKRRRNRCQ FCRFQKCLAV GMVKEVVRTD SLKGRRGRLP
360 370 380 390 400
SKPKQPPDAS PANLLTSLVR AHLDSGPSTA KLDYSKFQEM VLPHFGKEDA
410 420 430 440 450
GDVQQFYDLL SGSLEVIRKW AEKVPGFAEL SPGDQDLLLE SAFLELFILR
460 470 480 490 500
LAYRSKPAEG KLIFCSGLVL HRLQCARGFG DWIDSILAFS RSLHSLVVDV
510 520 530 540 550
PAFACLSALV LITADRHGLQ EPRRVEELQN CIASCLKEHI SAMSGEPQPA
560 570 580 590
SCLSRLLGKL PELRTLCTQG LQRIFYLKLE DLVPPPPIVD KIFMDTLPF
Length:599
Mass (Da):64,496
Last modified:April 12, 2017 - v1
Checksum:i938A6198BC9575EA
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1S2ZEV1A0A1S2ZEV1_ERIEU
nuclear receptor subfamily 4 group ...
NR4A1
598Annotation score:

Sequence databases

RefSeqiXP_016041538.1, XM_016186052.1
XP_016041539.1, XM_016186053.1

Genome annotation databases

GeneIDi103109192

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_016041538.1, XM_016186052.1
XP_016041539.1, XM_016186053.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103109192

Organism-specific databases

CTDi3164

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR003071 Nuc_orp_HMR_rcpt
IPR003070 Nuc_orph_rcpt
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01285 HMRNUCRECPTR
PR01284 NUCLEARECPTR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S3W4X5_ERIEU
AccessioniPrimary (citable) accession number: A0A1S3W4X5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: May 23, 2018
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again