Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Poly [ADP-ribose] polymerase

Gene

parp1

Organism
Salmo salar (Atlantic salmon)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Poly [ADP-ribose] polymeraseUniRule annotation (EC:2.4.2.30UniRule annotation)
Short name:
PARPUniRule annotation
Gene namesi
Name:parp1Imported
OrganismiSalmo salar (Atlantic salmon)Imported
Taxonomic identifieri8030 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeSalmo
Proteomesi
  • UP000087266 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 49PARP-typeInterPro annotationAdd BLAST49
Domaini70 – 160PARP-typeInterPro annotationAdd BLAST91
Domaini343 – 419BRCTInterPro annotationAdd BLAST77
Domaini619 – 736PARP alpha-helicalInterPro annotationAdd BLAST118
Domaini745 – 971PARP catalyticInterPro annotationAdd BLAST227

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili172 – 199Sequence analysisAdd BLAST28
Coiled coili356 – 376Sequence analysisAdd BLAST21
Coiled coili387 – 407Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

CDDicd00027 BRCT, 1 hit
Gene3Di1.20.142.10, 1 hit
2.20.140.10, 1 hit
2.20.25.630, 1 hit
3.30.1740.10, 2 hits
3.40.50.10190, 1 hit
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR012982 PADR1
IPR038650 PADR1_dom_sf
IPR008288 PARP
IPR012317 Poly(ADP-ribose)pol_cat_dom
IPR004102 Poly(ADP-ribose)pol_reg_dom
IPR036616 Poly(ADP-ribose)pol_reg_dom_sf
IPR036930 WGR_dom_sf
IPR008893 WGR_domain
IPR001510 Znf_PARP
IPR036957 Znf_PARP_sf
PfamiView protein in Pfam
PF00533 BRCT, 1 hit
PF08063 PADR1, 1 hit
PF00644 PARP, 1 hit
PF02877 PARP_reg, 1 hit
PF05406 WGR, 1 hit
PF00645 zf-PARP, 2 hits
PIRSFiPIRSF000489 NAD_ADPRT, 1 hit
SMARTiView protein in SMART
SM00292 BRCT, 1 hit
SM01335 PADR1, 1 hit
SM00773 WGR, 1 hit
SM01336 zf-PARP, 2 hits
SUPFAMiSSF142921 SSF142921, 1 hit
SSF47587 SSF47587, 1 hit
SSF52113 SSF52113, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 1 hit
PS51060 PARP_ALPHA_HD, 1 hit
PS51059 PARP_CATALYTIC, 1 hit
PS00347 PARP_ZN_FINGER_1, 1 hit
PS50064 PARP_ZN_FINGER_2, 2 hits

Sequencei

Sequence statusi: Complete.

A0A1S3SA00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDGKVPHWH HFSCFWLRAS AQSPADIAGF SDLRWEDQEK VKKAIETGGA
60 70 80 90 100
AGGKGDVKGG AKGEKTLNDF AVEYAKSNRS TCKGCEQKIE KDQIRVSKKT
110 120 130 140 150
VDPEKPQLGL IDRWYHTACF VGRREELVFK PEYSAAQLKG FNTLRVEDKE
160 170 180 190 200
ELKRRLPAVK SKGKRKTDEV DGEGASKKKK DEEEEKKKVE LQMKEQSQLI
210 220 230 240 250
WGIKDKLRQF CSTNDMKELL IANGQEVPSG ESNVVDSLGD CMAFGALKPC
260 270 280 290 300
EECQGQLVFK SDAYYCTGDL SAWTKCVFKT QLPNRKDWVI PKEFHELPFL
310 320 330 340 350
KKFKFKRQDR VFPKVAPAPP PASSAAVPCA SSAPSIPLPE GAPADKPLTG
360 370 380 390 400
MKLLTVGKLR QNKDELKAAV EELGGKITGT ANKATLCLST KKEVEKMSKK
410 420 430 440 450
MEEAEEVGVR VVSEDFLTDI KSSGKALQEL VSLHAISPWG AEVKLETQAQ
460 470 480 490 500
SAASRSGAMA GKSTKRVKEE EGVSKASKKM KLTVKGGAAV DPDSGLENSA
510 520 530 540 550
HVLDQNGKIF SATLGLVDIV RGTNSYYKLQ LLEDDVHKRY WVFRSWGRVG
560 570 580 590 600
TTIGGKKLDK FNDKNSAMDN FLGVYEEKTG NAWGSSHFTK YPNRFYPLEI
610 620 630 640 650
DYGQDEEAVK RLTASAGTNS LLAKPVQELI RTIFDVESMK KAMVEFEIDL
660 670 680 690 700
QKMPLGKLSK RQIQSAYALL SEVQQAVSDS SSESHILDLS NRFYTLIPHD
710 720 730 740 750
FGMKKPPLLR NLDYIQAKVQ MLDNLLDIEV AYSLLKGGAE DNKKDPIDIN
760 770 780 790 800
YEKLKTKIEV VDKTTKEAEI ILQYVKNTHA ATHNTYTLEV EEIFKIVREG
810 820 830 840 850
EYQKYRPFQD LPNRQLLWHG SRATNYAGIL SQGLRIAPPE APVTGYMFGK
860 870 880 890 900
GVYFADMVSK SANYCHTSQS DPTGLLLLGE VALGNMHELK KASHITKLPK
910 920 930 940 950
GKHSVKGLGR NAPDPSATVT LDGVQVPLGK GTNTNIDDTS LLYNEYIVYD
960 970
VAQVNLKYLL KIKFNYQMSM W
Length:971
Mass (Da):108,185
Last modified:April 12, 2017 - v1
Checksum:i9E99DAFF79A51867
GO

Sequence databases

RefSeqiXP_014061167.1, XM_014205692.1
UniGeneiSsa.14974

Genome annotation databases

GeneIDi100380653

Similar proteinsi

Entry informationi

Entry nameiA0A1S3SA00_SALSA
AccessioniPrimary (citable) accession number: A0A1S3SA00
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: April 25, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health