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Protein
Submitted name:

helicase ARIP4

Gene

rad54l2

Organism
Salmo salar (Atlantic salmon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
helicase ARIP4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rad54l2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSalmo salar (Atlantic salmon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8030 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeSalmo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000087266 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini377 – 597Helicase ATP-bindingInterPro annotationAdd BLAST221
Domaini807 – 976Helicase C-terminalInterPro annotationAdd BLAST170

Phylogenomic databases

KEGG Orthology (KO)

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KOi
K10876

Database of Orthologous Groups

More...
OrthoDBi
815681at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00079 HELICc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1S3L943-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEEAISGSD LDPSVNSEEE EEEEIEDEDN NDGDDEDDAV ERPESGQGST
60 70 80 90 100
ETETQGGRDS PSATSPSEET PSEPPSQPSS QPPSRASSRP NSRPESRSQP
110 120 130 140 150
PSGPSSQPPS RPESPSQDKP STGKKKKPRA SKSQAPSSCP ETPSKDKTSV
160 170 180 190 200
GKKKKPRTSK SKEPKLAKPS KTLHMRKNIR KLLKEHQMEA VTKAAQQEEL
210 220 230 240 250
ERLRRLEQQR KDFMAPPVQE FPPAVEAVSG RPGEEEFQGQ GSLEAAFLAR
260 270 280 290 300
QDVICLDSSD SSGEEEEDTK PPAIPTITPT IRDDVIELSS GDDDTLPISS
310 320 330 340 350
ESANEDEGAG GTEESSGAHI NDSLNQPDAQ GRVLVNINHP AEEEDLYLVP
360 370 380 390 400
QLARAVKPHQ VGGIRFLYDN LVESLERYKG SSGFGCILAH SMGLGKTLQV
410 420 430 440 450
ISFIDILLRH TEAHTVLAIV PVNTLQNWLA EFNLWLPSQE ALPPDSDPAT
460 470 480 490 500
VAGRTFRVHI LNDEHKTTVA RAKVVEDWSR DGGVLLMGYE MYRLLSLKKS
510 520 530 540 550
FVTGRKRKSK KPQGPVIIDL DEEDRQQELM KGIEKALARP GPDVVICDEG
560 570 580 590 600
HRIKNYHAST SQALKNIRSR RRVVLTGYPL QNNLIEYWCM VDFVRPDFLG
610 620 630 640 650
TRQEFSNMFE RPILNGQCVD STPQDARLMR YRSHVLHSLL EGFVQRRGHD
660 670 680 690 700
VLRDQLPSKD EHVIMVRLSP LQRALYAEFM DRFREAGNSG WLGLNPLKAF
710 720 730 740 750
CVCCKIWNHP DVLYETLQKE NLANEQDLDL DDITAAANPR CPAPGAGLKT
760 770 780 790 800
KAADSANSRS NVTLPPLNPI QERANQVITY EWAKDIMSNY QTGVLENSAK
810 820 830 840 850
MLLLFHLIDE SVIRGDKILV FSQSLSTLTV IEDFLTRRPM PAVRVSPDNH
860 870 880 890 900
GQNQTWVRNI NYYRLDGSTS ASERERLINQ FNDPENTSTW VFLLSTRAGC
910 920 930 940 950
LGVNLIGANR VVVFDASWNP CHDAQAVCRV YRYGQKKPCH IYRLVCDFTL
960 970 980 990 1000
EKKIYDRQVS KQGMSDRVVD DLNPVLTFTR KEVESLLHFA EEEPDPTKAP
1010 1020 1030 1040 1050
PQPHKEMETV ISQACQLYPH LITKEPFHHE SLLVDRKESK LTKAEKRAAK
1060 1070 1080 1090 1100
KSYEDEKRAS VPYSRPSYAH YYPTSDQTLI NIPAFNQRNW RPIARGDEKP
1110 1120 1130 1140 1150
VASVRPVQST PIPMMPRMAG MGVAGSSSGV GFPVNYLQKA GVYVQRIVTT
1160 1170 1180 1190 1200
TDIVIPGANS TTDVQARIGA GESIHMIKGS KGTYIKTNDG RIFAIRSGKL
1210 1220 1230 1240 1250
SRAVQGGTAT NRGSQVSLLH AIGNGCSSPG ERQRLTPDSA LWPSTPEILR
1260 1270 1280 1290 1300
ELSRYAVTAD TVTVGNELPS PSDTFTGDRG GGGRMQQHNQ TTESDHSRQF
1310 1320 1330 1340 1350
REDVGMSISE ALQRSKRKMA ESRGHKQGGK RSSTAAGFPG LSLGSGGLSF
1360 1370 1380 1390 1400
PPMNQALEGH MSHPLLMGGN SSSPFLQSAG QTLGDLQAMF PSAGADLLNH
1410 1420 1430 1440 1450
ASSATGSNGH LPSSTTTSTN TMPVSSASTT LPPYLMNPSV ADLLSPGFPL
1460 1470 1480 1490 1500
NYSQSLLPDP RMYPNTLGGG PASSGGSSSF LSHYPSSPSS LLGAALSRPD
1510 1520
THHMATDNGG SSSDDDVIEV TGQ
Length:1,523
Mass (Da):167,194
Last modified:April 12, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF5F65C295F8E372E
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_013987480.1, XM_014132005.1
XP_013987481.1, XM_014132006.1
XP_013987482.1, XM_014132007.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
106565170

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sasa:106565170

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_013987480.1, XM_014132005.1
XP_013987481.1, XM_014132006.1
XP_013987482.1, XM_014132007.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi106565170
KEGGisasa:106565170

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23132

Phylogenomic databases

KOiK10876
OrthoDBi815681at2759

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1S3L943_SALSA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1S3L943
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: January 16, 2019
This is version 11 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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