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UniProtKB - A0A1S3JJQ6 (A0A1S3JJQ6_LINUN)

Entry version 13 (10 Feb 2021)
Sequence version 1 (12 Apr 2017)
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Protein
Submitted name:

oral-facial-digital syndrome 1 protein homolog

Gene

LOC106173529

Organism
Lingula unguis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
oral-facial-digital syndrome 1 protein homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LOC106173529Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLingula unguisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7574 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Spiralia › Lophotrochozoa › Brachiopoda › Linguliformea › Lingulata › Lingulida › Linguloidea › Lingulidae › Lingula
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000085678 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini96 – 128LisHInterPro annotationAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni679 – 707DisorderedSequence analysisAdd BLAST29
Regioni730 – 757DisorderedSequence analysisAdd BLAST28
Regioni772 – 1066DisorderedSequence analysisAdd BLAST295
Regioni1096 – 1140DisorderedSequence analysisAdd BLAST45
Regioni1168 – 1204DisorderedSequence analysisAdd BLAST37

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili257 – 284Sequence analysisAdd BLAST28
Coiled coili286 – 342Sequence analysisAdd BLAST57
Coiled coili350 – 370Sequence analysisAdd BLAST21
Coiled coili394 – 445Sequence analysisAdd BLAST52
Coiled coili466 – 511Sequence analysisAdd BLAST46
Coiled coili519 – 546Sequence analysisAdd BLAST28
Coiled coili576 – 596Sequence analysisAdd BLAST21
Coiled coili1145 – 1165Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi680 – 707PolarSequence analysisAdd BLAST28
Compositional biasi779 – 808PolarSequence analysisAdd BLAST30
Compositional biasi832 – 848PolyampholyteSequence analysisAdd BLAST17
Compositional biasi849 – 866PolarSequence analysisAdd BLAST18
Compositional biasi966 – 981PolarSequence analysisAdd BLAST16
Compositional biasi998 – 1027PolyampholyteSequence analysisAdd BLAST30
Compositional biasi1041 – 1066PolyampholyteSequence analysisAdd BLAST26

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Database of Orthologous Groups

More...OrthoDBi		294646at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR006594, LisH

Pfam protein domain database

More...Pfami		View protein in Pfam
PF16045, LisH_2, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50896, LISH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1S3JJQ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTNELILPI AEYFCRFSLC GTVQGSLLVY NMSTSTSVLS ADELKHKLYS 
        60         70         80         90        100
SLRGKGVLDS LKSQLRNKLV HELQHSVLGS SLKTKPPQQQ ADSSLSLTAA 
       110        120        130        140        150
NSLVADHLRR CHYNYSLGVF IPESGASQDK VFTTQDLLQL LHISPHSKLY 
       160        170        180        190        200
KTLTESMPES SSKGFLWQLL TALAGSHAGL SQDTSTQTSR DGHGAMSILS 
       210        220        230        240        250
TRLSKVDEEF DTLLHENSKS HALGTEERIL SIQRHLEERF KEETKLELER 
       260        270        280        290        300
FKETQFTKFK LQEKEKARKE IEKARKEMEQ TYRAKCDALS ERERAATERL 
       310        320        330        340        350
QRRQEQQEKE LYQQRQSLLE EIDKVREREV EVRKDLEIMK RESQLHEDKM 
       360        370        380        390        400
KSWEGVLKKR EDSVHRLEEE FDQRLQIDVA RFKIEEQGRL LERTKNLEVQ 
       410        420        430        440        450
EARLSDELKR LGEEREAQQS VREELRINKA RVAELEAQIQ ALHHEKISTS 
       460        470        480        490        500
KHYEVAQERL RETVDYRSIK EENAVMKREL ETTKMRQAEL LHENERERQR 
       510        520        530        540        550
YESLLKDMGE RTKQPTPESL LLQRELQRAQ DRLKQEQAVF EHQKQQSDAR 
       560        570        580        590        600
IKEEADRNQE ILKKFEEQTL QQREMIREIT DLRQQLLHTQ EALNNEIYRK 
       610        620        630        640        650
PRTATLRPQS TAAYMDDMPV HDPGINDMYI DTSLRRTRVD PELQLAGDVS 
       660        670        680        690        700
YSGGYGSNSV APDINDLLDR VDRELKGADN NMLTTLQRQQ RQQDGGSPDE 
       710        720        730        740        750
SSATDIILET RQRLQRLERE AEEFDENYRQ FNQRMTNPVA VPDDSYLQPQ 
       760        770        780        790        800
SRRTPKTAAT AAYRVVFDDL PPAPSPLTGS PLRQNTKTSP YSSPSKYTGG 
       810        820        830        840        850
ATYSSSPTRL RSEERRSSER GRPLSSTPFR KTRRTLTHDD DETPDRHSPP 
       860        870        880        890        900
TLDGSTSPTS HGNEGYLPSL GMSEVTKRIS PVDNREKSPL TRQGPLTLND 
       910        920        930        940        950
LEGRPGSPGV VVFQGSGTSS KTSDHSGHDP AVDLDIGGNQ VTRPQDHPTT 
       960        970        980        990       1000
WHGDHRGDTP TPATEMDLSI KDNSVTGASR QDKSVRRVDP NDSQPSEPVR 
      1010       1020       1030       1040       1050
LVEHDDSSDR RERPMEEKEE GSNHLDAGAE EEPQVVSLDS TWKVKEDEEK 
      1060       1070       1080       1090       1100
KRQEKRRQIE REQREWVEQR RKIEEEKLRQ EQEEWEREQQ KLEKLRKEKE 
      1110       1120       1130       1140       1150
KEKEKNLTPE AQVKVEKVEE EKVEEKEEKK DDKEPEIDPV MQKYMEMLKK 
      1160       1170       1180       1190       1200
KKEEEKKEAE IATKAVKVWS KGHQSEEKSQ SEHELSVADE EKSIGGFSDD 

DFEW
Length:1,204
Mass (Da):139,256
Last modified:April 12, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE26375C7BDBBD87F
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_013410139.1, XM_013554685.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		106173529

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		lak:106173529

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_013410139.1, XM_013554685.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi106173529
KEGGilak:106173529

Phylogenomic databases

OrthoDBi294646at2759

Family and domain databases

InterProiView protein in InterPro
IPR006594, LisH
PfamiView protein in Pfam
PF16045, LisH_2, 1 hit
PROSITEiView protein in PROSITE
PS50896, LISH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1S3JJQ6_LINUN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1S3JJQ6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: February 10, 2021
This is version 13 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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