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Protein

Protein-tyrosine sulfotransferase

Gene

Tpst1

Organism
Dipodomys ordii (Ord's kangaroo rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.UniRule annotation

Catalytic activityi

3'-phosphoadenylyl sulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-tyrosine sulfotransferaseUniRule annotation (EC:2.8.2.20UniRule annotation)
Gene namesi
Name:Tpst1Imported
OrganismiDipodomys ordii (Ord's kangaroo rat)Imported
Taxonomic identifieri10020 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaCastorimorphaHeteromyidaeDipodomyinaeDipodomys
Proteomesi
  • UP000081671 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the protein sulfotransferase family.UniRule annotation

Phylogenomic databases

OMAiHIPWNHS

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR026634 TPST
PANTHERiPTHR12788 PTHR12788, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits

Sequencei

Sequence statusi: Complete.

A0A1S3GIL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGKLKQNLL LACLVISSVT VFYLGQHAME CHHRIEERSQ PVKLESIKTS
60 70 80 90 100
MQTGLDIKAN KTFAYHKDMP LIFIGGVPRS GTTLMRAMLD AHPDIRCGEE
110 120 130 140 150
TRVIPRILAL KQMWSRSSKE KIRLDEAGVT DDVLDSAMQA FLLEIIVKHG
160 170 180 190 200
EPAPYLCNKD PFALKSLTYL ARLFPNAKFL LMVRDGRASV HSMISRKVTI
210 220 230 240 250
AGFDLNSYRD CLTKWNRAIE TMYNQCVEVG YQKCMMVHYE QLVLHPERWM
260 270 280 290 300
RTLLKFLHIP WNHSVLHHEE MIGKAGGVSL SKVERSTDQV IKPVNVGALS
310 320 330 340 350
KWVGKIPGDV LQDMAVIAPM LAKLGYDPYA NPPNYGKPDP KILENTRRVY
360 370
KGEFQLPDFL KEKPQTEQVE
Length:370
Mass (Da):42,087
Last modified:April 12, 2017 - v1
Checksum:iCEF28D5D2CB5D035
GO

Sequence databases

RefSeqiXP_012888636.1, XM_013033182.1

Genome annotation databases

EnsembliENSDORT00000034693; ENSDORP00000025471; ENSDORG00000007420
GeneIDi105998472

Similar proteinsi

Entry informationi

Entry nameiA0A1S3GIL8_DIPOR
AccessioniPrimary (citable) accession number: A0A1S3GIL8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: June 20, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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