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Protein
Submitted name:

von Willebrand factor C and EGF domain-containing protein

Gene

Vwce

Organism
Dipodomys ordii (Ord's kangaroo rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
von Willebrand factor C and EGF domain-containing proteinImported
Gene namesi
Name:VwceImported
OrganismiDipodomys ordii (Ord's kangaroo rat)Imported
Taxonomic identifieri10020 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaCastorimorphaHeteromyidaeDipodomyinaeDipodomys
Proteomesi
  • UP000081671 Componenti: Genome assembly

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501036002522 – 941Sequence analysisAdd BLAST920

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini142 – 180EGF-likeInterPro annotationAdd BLAST39
Domaini181 – 219EGF-likeInterPro annotationAdd BLAST39
Domaini220 – 262EGF-likeInterPro annotationAdd BLAST43
Domaini376 – 433VWFCInterPro annotationAdd BLAST58
Domaini491 – 552VWFCInterPro annotationAdd BLAST62
Domaini558 – 618VWFCInterPro annotationAdd BLAST61
Domaini619 – 677VWFCInterPro annotationAdd BLAST59
Domaini677 – 735VWFCInterPro annotationAdd BLAST59

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR026823 cEGF
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR009030 Growth_fac_rcpt_cys_sf
IPR037578 Von_Willebrand_factor
IPR001007 VWF_dom
PANTHERiPTHR11339:SF361 PTHR11339:SF361, 3 hits
PfamiView protein in Pfam
PF12662 cEGF, 1 hit
PF07645 EGF_CA, 1 hit
PF00093 VWC, 4 hits
SMARTiView protein in SMART
SM00181 EGF, 4 hits
SM00179 EGF_CA, 3 hits
SM00214 VWC, 6 hits
SM00215 VWC_out, 5 hits
SUPFAMiSSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 3 hits
PS01186 EGF_2, 2 hits
PS50026 EGF_3, 3 hits
PS01187 EGF_CA, 1 hit
PS01208 VWFC_1, 4 hits
PS50184 VWFC_2, 5 hits

Sequencei

Sequence statusi: Complete.

A0A1S3G6Y1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWAGLFLWAA CTALLLPGAP APGYTGRKSS GHFLAERRRL GPHVCLSGFG
60 70 80 90 100
SGCCPGWAPS IGSGHCTLPL CSFGCGSGIC IAPNVCSCQG GEHGATCPES
110 120 130 140 150
HVSCGEYGCD LACNHGGCQE VARVCPVGFS MTETAVGIRC ADIDECLSSS
160 170 180 190 200
CEGQCVNTEG GFVCECGPGM QLSADRHSCQ DTNECLGTPC QQRCKNSFGS
210 220 230 240 250
YKCSCHSGFH LHGNRHSCVD INECRRPQER RVCHHSCHNT VGSFLCTCRP
260 270 280 290 300
GFRLRADRVS CEASPKAILA PSAILQPRQH PKMSLLLPEA GRPALSPGHG
310 320 330 340 350
APPGVPEPPA GIKTTHPPSP TPVPPTTSPT WLLFTPVPSA SLLGTLGPPS
360 370 380 390 400
FLQGEAVGTP SSPRGPENPR PETSPAPCWH LGTAYASGSH WLQPGCSQCW
410 420 430 440 450
CEDGEMTCEK LRCEATCSHP IPAGDQECCP SCTGCFHSGA IRAEGAVFSP
460 470 480 490 500
PNENCTVCVC LAGNVSCISP ECPPGPCDTH LQSDCCACVP VRCYFHGRWY
510 520 530 540 550
SDGAVFSGGG DECTTCICQN GEVECSFTPC PELNCPREEW WLGPGQCCFS
560 570 580 590 600
CQKPTPATGC SLDDNGVEFP IGQIWSPGDP CELCICQADG SVSCKRTDCV
610 620 630 640 650
DSCPHPIRIP GQCCPDCSAG CTYTGRIFYN NETFLSMLDP CLNCICLLGS
660 670 680 690 700
VACSPVDCPI ACTYPFHPDG ECCPVCRDCN YEGRKVMNGQ LFTLDDEPCT
710 720 730 740 750
QCTCQLGEVS CEKVPCHPAC MDPALPPGDC CSSCPDAPFP PEERQELSPQ
760 770 780 790 800
GDLGRSKAVQ SLHGDTEVLI NCSSCPGPPP TSPSRPALHF LQLLLRTNLS
810 820 830 840 850
NAQTLPAGPP EAQASASSPP GPRATFPGES GASRPPWSTS GSSVPAGPSA
860 870 880 890 900
LPPTSLGILG PPAAPESSFS ASGAQTVSRW PLRANLLTET LGQSMMDHGS
910 920 930 940
SETPTIPLRP SRLSVALVAT THLGPQQPTT GLSREDEEST V
Length:941
Mass (Da):98,774
Last modified:April 12, 2017 - v1
Checksum:iBE6C2444D7D62091
GO

Sequence databases

RefSeqiXP_012884445.1, XM_013028991.1

Genome annotation databases

GeneIDi105995283

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_012884445.1, XM_013028991.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi105995283

Organism-specific databases

CTDi220001

Family and domain databases

InterProiView protein in InterPro
IPR026823 cEGF
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR009030 Growth_fac_rcpt_cys_sf
IPR037578 Von_Willebrand_factor
IPR001007 VWF_dom
PANTHERiPTHR11339:SF361 PTHR11339:SF361, 3 hits
PfamiView protein in Pfam
PF12662 cEGF, 1 hit
PF07645 EGF_CA, 1 hit
PF00093 VWC, 4 hits
SMARTiView protein in SMART
SM00181 EGF, 4 hits
SM00179 EGF_CA, 3 hits
SM00214 VWC, 6 hits
SM00215 VWC_out, 5 hits
SUPFAMiSSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 3 hits
PS01186 EGF_2, 2 hits
PS50026 EGF_3, 3 hits
PS01187 EGF_CA, 1 hit
PS01208 VWFC_1, 4 hits
PS50184 VWFC_2, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S3G6Y1_DIPOR
AccessioniPrimary (citable) accession number: A0A1S3G6Y1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: July 18, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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