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Protein

RBR-type E3 ubiquitin transferase

Gene

RNF217

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N6-ubiquitinyl-L-lysine.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionLigaseImported, TransferaseSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RBR-type E3 ubiquitin transferaseSAAS annotation (EC:2.3.2.31SAAS annotation)
Gene namesi
Name:RNF217Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei492 – 521HelicalSequence analysisAdd BLAST30

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini321 – 389IBR-typeInterPro annotationAdd BLAST69
Domaini396 – 467IBR-typeInterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the RBR family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis, Zinc-fingerSAAS annotation

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR031127 E3_UB_ligase_RBR
IPR002867 IBR_dom
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR11685 PTHR11685, 1 hit
PfamiView protein in Pfam
PF01485 IBR, 2 hits
SMARTiView protein in SMART
SM00647 IBR, 2 hits

Sequencei

Sequence statusi: Complete.

A0A1S3AK05-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGEEQSTVSG RDAPPEARAA ASGAAGHHEP PGPRGCSAGE PGPRATSAEP
60 70 80 90 100
GGGGCEADPG CADTGAPEPA RTPESQGLEP STGLSPAGLL TPRTLQLQLE
110 120 130 140 150
KEDGAGDSNE GGYGPREVPP GEEREPGTPV GTAAADSLAL DVLGQRRRLP
160 170 180 190 200
ASRQVFCSVY CVENDLPRAS STSQLSPPAS PPRIPPVTTP PGTPSSFPSP
210 220 230 240 250
RLSLPADPLS SDGGGIELEF YLAPEPFSVS SLLGAPPYSG LGGVGDPYAP
260 270 280 290 300
LMVLMCRVCL EDKPIKPLPC CKKAVCEECL KVYLSAQVQL GQVEIKCPIT
310 320 330 340 350
ECFEFLEETT VTYNLTHEDS IKYKYFLELG RIDSSTKPCP QCKHFTTFKK
360 370 380 390 400
KGHIPTPSRS ESKYKIQCPT CQFIWCFKCH SPWHEGVNCK EYKKGDKLLR
410 420 430 440 450
HWASEIEHGQ RNAQKCPKCK IHIQRTEGCD HMTCSQCNTN FCYRCGERYR
460 470 480 490 500
QLRFFGDHTS NLSIFGCKYR YLPERPHLRR LVRGSVCAGK LFVAPLILVL
510 520 530
GLALGAIAVV IGLFVFPIYC LCKKQRKRSR TGMHW
Length:535
Mass (Da):58,149
Last modified:April 12, 2017 - v1
Checksum:i492685358B679C7F
GO

Sequence databases

RefSeqiXP_007536171.1, XM_007536109.1

Genome annotation databases

GeneIDi103125338

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_007536171.1, XM_007536109.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103125338

Organism-specific databases

CTDi154214

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR031127 E3_UB_ligase_RBR
IPR002867 IBR_dom
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR11685 PTHR11685, 1 hit
PfamiView protein in Pfam
PF01485 IBR, 2 hits
SMARTiView protein in SMART
SM00647 IBR, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S3AK05_ERIEU
AccessioniPrimary (citable) accession number: A0A1S3AK05
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: May 23, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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