Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

laminin subunit beta-2

Gene

LAMB2

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
laminin subunit beta-2Imported
Gene namesi
Name:LAMB2Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 35Sequence analysisAdd BLAST35
ChainiPRO_501024443636 – 1802Sequence analysisAdd BLAST1767

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi317 ↔ 326PROSITE-ProRule annotation
Disulfide bondi382 ↔ 391PROSITE-ProRule annotation
Disulfide bondi445 ↔ 454PROSITE-ProRule annotation
Disulfide bondi498 ↔ 507PROSITE-ProRule annotation
Disulfide bondi510 ↔ 524PROSITE-ProRule annotation
Disulfide bondi527 ↔ 539PROSITE-ProRule annotation
Disulfide bondi529 ↔ 546PROSITE-ProRule annotation
Disulfide bondi548 ↔ 557PROSITE-ProRule annotation
Disulfide bondi787 ↔ 799PROSITE-ProRule annotation
Disulfide bondi789 ↔ 806PROSITE-ProRule annotation
Disulfide bondi808 ↔ 817PROSITE-ProRule annotation
Disulfide bondi835 ↔ 847PROSITE-ProRule annotation
Disulfide bondi837 ↔ 854PROSITE-ProRule annotation
Disulfide bondi856 ↔ 865PROSITE-ProRule annotation
Disulfide bondi900 ↔ 909PROSITE-ProRule annotation
Disulfide bondi960 ↔ 969PROSITE-ProRule annotation
Disulfide bondi1014 ↔ 1023PROSITE-ProRule annotation
Disulfide bondi1071 ↔ 1080PROSITE-ProRule annotation
Disulfide bondi1099 ↔ 1111PROSITE-ProRule annotation
Disulfide bondi1101 ↔ 1118PROSITE-ProRule annotation
Disulfide bondi1120 ↔ 1129PROSITE-ProRule annotation
Disulfide bondi1147 ↔ 1159PROSITE-ProRule annotation
Disulfide bondi1149 ↔ 1166PROSITE-ProRule annotation
Disulfide bondi1168 ↔ 1177PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 287Laminin N-terminalInterPro annotationAdd BLAST240
Domaini288 – 351Laminin EGF-likeInterPro annotationAdd BLAST64
Domaini352 – 414Laminin EGF-likeInterPro annotationAdd BLAST63
Domaini415 – 474Laminin EGF-likeInterPro annotationAdd BLAST60
Domaini475 – 526Laminin EGF-likeInterPro annotationAdd BLAST52
Domaini527 – 567Laminin EGF-likeInterPro annotationAdd BLAST41
Domaini566 – 781Laminin IV type BInterPro annotationAdd BLAST216
Domaini787 – 834Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini835 – 880Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini881 – 930Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini931 – 989Laminin EGF-likeInterPro annotationAdd BLAST59
Domaini990 – 1041Laminin EGF-likeInterPro annotationAdd BLAST52
Domaini1042 – 1098Laminin EGF-likeInterPro annotationAdd BLAST57
Domaini1099 – 1146Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini1147 – 1193Laminin EGF-likeInterPro annotationAdd BLAST47

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1205 – 1225Sequence analysisAdd BLAST21
Coiled coili1266 – 1307Sequence analysisAdd BLAST42
Coiled coili1481 – 1529Sequence analysisAdd BLAST49
Coiled coili1577 – 1621Sequence analysisAdd BLAST45
Coiled coili1636 – 1663Sequence analysisAdd BLAST28
Coiled coili1685 – 1705Sequence analysisAdd BLAST21
Coiled coili1728 – 1783Sequence analysisAdd BLAST56

Keywords - Domaini

Coiled coilSequence analysis, Laminin EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR000742 EGF-like_dom
IPR002049 Laminin_EGF
IPR013015 Laminin_IV_B
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
PfamiView protein in Pfam
PF00053 Laminin_EGF, 13 hits
PF00055 Laminin_N, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 10 hits
SM00180 EGF_Lam, 13 hits
SM00136 LamNT, 1 hit
PROSITEiView protein in PROSITE
PS01248 EGF_LAM_1, 6 hits
PS50027 EGF_LAM_2, 13 hits
PS51116 LAMININ_IVB, 1 hit
PS51117 LAMININ_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1S3AE81-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEQTLGEAGR HRWAQPASWE LQLGLLLSVL ATTLAQALAP DMDVPGCSRG
60 70 80 90 100
SCYPATGDLL VGRADRLTAS STCGLRGPQP YCIVSHLQDE KKCFLCDSRH
110 120 130 140 150
PFSARENPNS HRIQNVVTSF APQRRTAWWQ SENGVPLVTI QLDLEAEFHF
160 170 180 190 200
THLIMTFKTF RPAAMLVERS SDFGRTWHVY RYFSYDCAAD YPGIPLAPPR
210 220 230 240 250
HWDDIVCESR YSEIEPSTEG EVIYRVLDPA IPIPDPYSPR IQNLLKITNL
260 270 280 290 300
RVNLTRLHTL GDNLLDPRRE IREKYYYALY ELVVRGNCFC YGHASQCAPA
310 320 330 340 350
PGAPAHAEGM VHGACVCKHN TRGLNCEQCQ DFYHDLPWHP AEDGHSHACR
360 370 380 390 400
KCECHGHAHS CHFDMAVYLA SGNMSGGVCD GCQHNTAGRH CEFCRPFFYR
410 420 430 440 450
DPVKDMRDPA VCRPCDCDPT GSKDGGRCDP HDDPALGLVS GQCRCKEHVV
460 470 480 490 500
GSRCQQCRDG FFGLSASDPV GCQPCQCDAR GTVPGRTPCD PNSGTCFCKR
510 520 530 540 550
LVTGRGCSRC LPGHWGLSHD LLGCRPCDCD VGGALDPQCN EATGQCRCRQ
560 570 580 590 600
HMVGRRCEQV QPGYFRPFLD HLTWEAEDTR GQVLDVVERL VTPGGTPSWT
610 620 630 640 650
GQGFVRLQQG QALEFQVTSV PKAMEYDLLL RLEPQVPEQW AEIELTLQRP
660 670 680 690 700
GPVSAHSLCR HVPEDDHISA TLRPNARYIV LPRPVCLEPG ISYKLHLKLV
710 720 730 740 750
RTGGSTQPEA PYSRPSLLID SLVLLPRVLT LEMFSGGDSA ALERRAIFER
760 770 780 790 800
YRCHEEGLVT SKTLPSEACA PLLISLSALL YNGALPCQCD PQGSLSSECN
810 820 830 840 850
PHGGQCRCKP SVVGRRCDRC APGYYGFGPA GCQACQCSPE GALSGLCDGT
860 870 880 890 900
SGQCPCRAGA FGLRCDHCQR GQWGFPRCRP CVCNGHADEC DTHTGACLGC
910 920 930 940 950
RDHTGGEHCD RCIAGFHGDP RLPYGGQCRP CPCPEGPGSQ RHFATSCHRD
960 970 980 990 1000
GHSQQIVCHC RAGYTGLRCE VCAPGHFGDP SRPGGRCQPC ECSGNIDPMD
1010 1020 1030 1040 1050
PGACDPRTGR CLRCLHHTEG PHCAHCKPGF HGQAARQSCH RCTCNQLGTD
1060 1070 1080 1090 1100
PQRCPSTDRC HCDPSSGQCP CLPNVQGPSC DRCAPSFWNL TSGHGCQPCA
1110 1120 1130 1140 1150
CHPSRARGPT CNEFTGQCHC RAGFGGRTCS ECQELHWGDP GLQCRACDCD
1160 1170 1180 1190 1200
PRGIDSPQCH RSTGHCSCRP GVSGVRCDQC ARGFSGVFPA CYPCHACFGD
1210 1220 1230 1240 1250
WDRVVQDLAS RTRRLEQQVQ ELQQTGVLGT FESSFWHMQE KLGIVQGFVS
1260 1270 1280 1290 1300
ARNTSTAATA LLLKTTEDLR REIGEATEHL TQLEAELTDV QDENFNANHA
1310 1320 1330 1340 1350
LSNLERDGLA LNLTLRQLHQ HLDLIKHSNF LGAYDSIRQA HSLSVEAERR
1360 1370 1380 1390 1400
ANTSALTVPS PVSNSAGIRQ QTEALMSVQR ENFNRRHMAN QQALDELSAR
1410 1420 1430 1440 1450
TQTLSLTGIN ELVCGSPGDE PCATSPCGGA GCRDEDGQPR CGGLGCSGAA
1460 1470 1480 1490 1500
AVADLALGRA RHTQAELQRA LEGGGSIFSQ VAETRRQAGE AQQRAQAALD
1510 1520 1530 1540 1550
KANASRGQVE QANQELRELI QSVKDFLSQE GANPDSIEMV ATRVLEISIP
1560 1570 1580 1590 1600
ASPEQIQHLA GEIAVRVRSL ADVDTILART VGDVRRAEQL LQDARRARNW
1610 1620 1630 1640 1650
AEDEKRKTEV VQAALEEAQR AQGVAQGAIQ GAVADTQDTE QTLKQVQERM
1660 1670 1680 1690 1700
AGAEKALSSA GERAQQLDVL LEALKLKRAG NSLAASSAEE TANSAQGRAR
1710 1720 1730 1740 1750
EAEQLLQGPV GDKYQTVRDL AERKAQGVLV AQERAEQLRN EARSLLQAAQ
1760 1770 1780 1790 1800
DKLQRLQELE GTYEENERAL EGKAAQLDGL EARMRSVLQA INLQVQIYNT

CQ
Length:1,802
Mass (Da):196,962
Last modified:April 12, 2017 - v1
Checksum:i5B32F6F2668B79B7
GO

Sequence databases

RefSeqiXP_007533627.1, XM_007533565.1

Genome annotation databases

GeneIDi103122957

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_007533627.1, XM_007533565.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103122957

Organism-specific databases

CTDi3913

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR000742 EGF-like_dom
IPR002049 Laminin_EGF
IPR013015 Laminin_IV_B
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
PfamiView protein in Pfam
PF00053 Laminin_EGF, 13 hits
PF00055 Laminin_N, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 10 hits
SM00180 EGF_Lam, 13 hits
SM00136 LamNT, 1 hit
PROSITEiView protein in PROSITE
PS01248 EGF_LAM_1, 6 hits
PS50027 EGF_LAM_2, 13 hits
PS51116 LAMININ_IVB, 1 hit
PS51117 LAMININ_NTER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S3AE81_ERIEU
AccessioniPrimary (citable) accession number: A0A1S3AE81
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: April 25, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again