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Protein
Submitted name:

voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X3

Gene

CACNA2D1

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X3Imported
Gene namesi
Name:CACNA2D1Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501025892925 – 1089Sequence analysisAdd BLAST1065

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini253 – 430VWFAInterPro annotationAdd BLAST178

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR013680 VDCC_a2/dsu
IPR013608 VWA_N
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF08473 VGCC_alpha2, 1 hit
PF00092 VWA, 1 hit
PF08399 VWA_N, 1 hit
SMARTiView protein in SMART
SM00327 VWA, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50234 VWFA, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

A0A1S3A1P8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAARCLLALT LTLFQFLLIG PSSEEPFPSA VTIKSWVDKM QEDLVTLAKT
60 70 80 90 100
ASGVNQLVDI YEKYQDLYTV EPNNARQLVE IAARDIEKLL SNRSKALVRL
110 120 130 140 150
AQEAERVQAA HQWREDFASN EVVYYNAKDD LDSEKNDSEP GSQRIKPVFT
160 170 180 190 200
EDANFGRQIS YQHAAVHIPT DIYEGSTIVL NELNWTSALD EVFKKNQEED
210 220 230 240 250
PSLLWQVFGS ATGLARYYPA SPWVDNSRTP NKIDLYDVRR RPWYIQGAAS
260 270 280 290 300
PKDMLILVDV SGSVSGLTLK LIRTSVSEML ETLSDDDFVN VASFNSNAQD
310 320 330 340 350
VSCFQHLVQA NVRNKKVLKD AVNNITAKGI TDYKKGFSFA FEQLLNYNVS
360 370 380 390 400
RANCNKIIML FTDGGEERAQ EIFTKYNKDK KVRVFTFSVG QHNYDRGPIQ
410 420 430 440 450
WMACENKGYY YEIPSIGAIR INTQEYLDVL GRPMVLAGEK AKQVQWTNVY
460 470 480 490 500
LDALELGLVI TGTLPVFNIT GQVENKTKNQ LILGVMGVDV SLEDIKRLTP
510 520 530 540 550
RFTLCPNGYY FAIDPNGYVL LHPNLQPKNP KSQEPVTLDF LDAELENDIK
560 570 580 590 600
VEIRNKMIDG ESGDRTFRTL VKSQDERYID KGNRTYTWTP VNGTDYSLAL
610 620 630 640 650
VLPTYSFYYI KAKIEETITQ ARSKKGKMKD SETLKPDNFE ESGYTFIAPR
660 670 680 690 700
DYCNDLKISE NNTEFLLNFN EFIDRKTPNN PSCNTDLINR VLLDAGFTNE
710 720 730 740 750
LVQNYWSKQK NIKGVKARFV VTDGGITRVY PKEAGENWQE NPETYEDSFY
760 770 780 790 800
KRSLDNDNYV FTAPNFNKSG PSAYESGIMV SKAVEIYIQG KLLKPAVVGI
810 820 830 840 850
KIDVNSWIEN FTKTSIRDPC AGPVCDCKRN SDVMDCVILD DGGFLLMANH
860 870 880 890 900
DDYTNQIGRF FGEIDPSLMR HLINISVYAF NKSYDYQSVC DPGAAPKQGA
910 920 930 940 950
GHRSAYVPSI ADILHIGWWA TAAAWSILQQ LLLSLTFPRL LEAVELEDED
960 970 980 990 1000
FASPLSKQSC ITEQTQYFFD NDSKSFSGVL DCGNCSRIFH VEKLMNTNLI
1010 1020 1030 1040 1050
FIMVESKGTC PCDTRQLIQA EQTSDGPDPC DMVKKPRYRK GPDVCFDNNV
1060 1070 1080
LEDYTDCGGV SGLNPSLWSI IGIQFVLLWL LSGSKHCQL
Length:1,089
Mass (Da):123,052
Last modified:April 12, 2017 - v1
Checksum:i770CEBED20FDC6EE
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1S3WHE2A0A1S3WHE2_ERIEU
voltage-dependent calcium channel s...
CACNA2D1
1,090Annotation score:
A0A1S3WI34A0A1S3WI34_ERIEU
voltage-dependent calcium channel s...
CACNA2D1
1,108Annotation score:
A0A1S3WI39A0A1S3WI39_ERIEU
voltage-dependent calcium channel s...
CACNA2D1
1,077Annotation score:
A0A1S3WHC9A0A1S3WHC9_ERIEU
voltage-dependent calcium channel s...
CACNA2D1
1,082Annotation score:
A0A1S3WHN0A0A1S3WHN0_ERIEU
voltage-dependent calcium channel s...
CACNA2D1
1,084Annotation score:
A0A1S3WHI8A0A1S3WHI8_ERIEU
voltage-dependent calcium channel s...
CACNA2D1
1,101Annotation score:

Sequence databases

RefSeqiXP_007527970.1, XM_007527908.1

Genome annotation databases

GeneIDi103117792

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_007527970.1, XM_007527908.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103117792

Organism-specific databases

CTDi781

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR013680 VDCC_a2/dsu
IPR013608 VWA_N
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF08473 VGCC_alpha2, 1 hit
PF00092 VWA, 1 hit
PF08399 VWA_N, 1 hit
SMARTiView protein in SMART
SM00327 VWA, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50234 VWFA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S3A1P8_ERIEU
AccessioniPrimary (citable) accession number: A0A1S3A1P8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: October 25, 2017
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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