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Protein

Palmitoyltransferase

Gene

ZDHHC12

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:ZDHHC12Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalUniRule annotationAdd BLAST21
Transmembranei44 – 64HelicalUniRule annotationAdd BLAST21
Transmembranei142 – 167HelicalUniRule annotationAdd BLAST26
Transmembranei179 – 204HelicalUniRule annotationAdd BLAST26

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini96 – 216DHHCInterPro annotationAdd BLAST121

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

A0A1S2ZZQ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPWALLSPG VLVRSGHTVL TWGITLVLFL HDTALRQWEE QGELLMPLTF
60 70 80 90 100
LLLVLGSLLL YLAVSLMDPG YVNVHPQPKE EAKEEQTAMV PQAIPLRRCG
110 120 130 140 150
YCLVLQPLRA RHCRECRRCV RRYDHHCPWM ENCVGERNHP LFVAYLALQL
160 170 180 190 200
VVLLWGLHLA WSGLRFFQPW GLWLRSSGLL FFTFLLLSLF SLVASLLLAS
210 220 230 240 250
HLYLVASNTT TWEFISSHRI TYLRQHQGNP FDRGLTRNLA HFFCGWPSGS
260
WEMLWAEEEG DQGDSNQAV
Length:269
Mass (Da):30,894
Last modified:April 12, 2017 - v1
Checksum:i02BF1D75CB71BEFE
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1S3WH41A0A1S3WH41_ERIEU
Palmitoyltransferase
ZDHHC12
265Annotation score:
A0A1S3WGN2A0A1S3WGN2_ERIEU
Palmitoyltransferase
ZDHHC12
267Annotation score:
A0A1S3WGD7A0A1S3WGD7_ERIEU
Palmitoyltransferase
ZDHHC12
268Annotation score:
A0A1S3WGJ2A0A1S3WGJ2_ERIEU
Palmitoyltransferase
ZDHHC12
227Annotation score:

Sequence databases

RefSeqiXP_007527117.1, XM_007527055.1

Genome annotation databases

GeneIDi103117057

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_007527117.1, XM_007527055.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103117057

Organism-specific databases

CTDi84885

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S2ZZQ8_ERIEU
AccessioniPrimary (citable) accession number: A0A1S2ZZQ8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: August 30, 2017
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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