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Protein
Submitted name:

ARF GTPase-activating protein GIT2 isoform X3

Gene

GIT2

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
ARF GTPase-activating protein GIT2 isoform X3Imported
Gene namesi
Name:GIT2Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 124Arf-GAPInterPro annotationAdd BLAST124
Domaini132 – 221ANK_REP_REGIONInterPro annotationAdd BLAST90
Repeati166 – 198ANKPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili408 – 428Sequence analysisAdd BLAST21
Coiled coili564 – 584Sequence analysisAdd BLAST21

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR022018 GIT1_C
IPR013724 GIT_SHD
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF01412 ArfGap, 1 hit
PF12205 GIT1_C, 1 hit
PF08518 GIT_SHD, 2 hits
PRINTSiPR00405 REVINTRACTNG
SMARTiView protein in SMART
SM00248 ANK, 3 hits
SM00105 ArfGap, 1 hit
SM00555 GIT, 2 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit
PS50115 ARFGAP, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

A0A1S2ZVM6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKRLRSSEV CADCSGPDPS WASVNRGTFI CDECCGVHRS LGRHISQVRH
60 70 80 90 100
LRHTPWPPTL LQMVETLYNN GANSIWEHSL LDPASLMSGR RKANPQDKVH
110 120 130 140 150
PNKAEFIRAK YQMLAFVHRL PCRDDDTVTA RDLSKQLHSS VRTGNLETCL
160 170 180 190 200
RLLSLGAQAN FFHPEKGNTP LHVASRAGQT LQAELLAVYG ADPATQDARG
210 220 230 240 250
ETPVDCARQG GHHGLAERLV EIQYELTDRL AFYLCGRKPD HKNGQHFLIP
260 270 280 290 300
QMADSSLDLS ELAKAAKKKL QSLSNHLFEE LAMDVYDEVD RRETDAVWLA
310 320 330 340 350
TQNHSTLVTE TTVVPFLPVN PEYSSTRNQG RQKLARFNAH EFATLVIDIL
360 370 380 390 400
SDARRRQQGS PLSGSKDNVE LILKAVSSQH SVESQDNDQP DYDSVASDED
410 420 430 440 450
ADLEATAGKA SRQKLQTLQS ENSNLRKQST ASVYQVQTAS EYPDTCKHSS
460 470 480 490 500
LKRRPSARGS RPMSMYETGS GHKPYLPLGD AERPEESRTR LPPFPAHASR
510 520 530 540 550
LEKQNSTPES DYDNTPNDRD ADDTGPGKKG RQSSTAWQGD GSVPDTAEPH
560 570 580 590 600
MAPSPVLPST EDVIRKTEQI TKNIQELLRA AQENKHDSYS PCSERIHDAV
610 620 630 640 650
TEMAALFPKK PKSDTARTSL RLLTSSAYRL QSECKKTLPG DLGPPADIQL
660 670
VTQQVIQCAY DIAKAAKQLV TITTKENSS
Length:679
Mass (Da):75,266
Last modified:April 12, 2017 - v1
Checksum:iA265D3AF2DBF1F0C
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1S2ZVM3A0A1S2ZVM3_ERIEU
ARF GTPase-activating protein GIT2 ...
GIT2
631Annotation score:
A0A1S2ZVL4A0A1S2ZVL4_ERIEU
ARF GTPase-activating protein GIT2 ...
GIT2
729Annotation score:
A0A1S2ZVL3A0A1S2ZVL3_ERIEU
ARF GTPase-activating protein GIT2 ...
GIT2
759Annotation score:
A0A1S2ZVN3A0A1S2ZVN3_ERIEU
ARF GTPase-activating protein GIT2 ...
GIT2
681Annotation score:

Sequence databases

RefSeqiXP_007525302.1, XM_007525240.1

Genome annotation databases

GeneIDi103115486

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_007525302.1, XM_007525240.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103115486

Organism-specific databases

CTDi9815

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR022018 GIT1_C
IPR013724 GIT_SHD
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF01412 ArfGap, 1 hit
PF12205 GIT1_C, 1 hit
PF08518 GIT_SHD, 2 hits
PRINTSiPR00405 REVINTRACTNG
SMARTiView protein in SMART
SM00248 ANK, 3 hits
SM00105 ArfGap, 1 hit
SM00555 GIT, 2 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit
PS50115 ARFGAP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S2ZVM6_ERIEU
AccessioniPrimary (citable) accession number: A0A1S2ZVM6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: March 28, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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