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Protein
Submitted name:

calmodulin-regulated spectrin-associated protein 1 isoform X5

Gene

CAMSAP1

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
calmodulin-regulated spectrin-associated protein 1 isoform X5Imported
Gene namesi
Name:CAMSAP1Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MicrotubulePROSITE-ProRule annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini201 – 316Calponin-homology (CH)InterPro annotationAdd BLAST116
Domaini1441 – 1575CKKInterPro annotationAdd BLAST135

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili178 – 198Sequence analysisAdd BLAST21
Coiled coili853 – 883Sequence analysisAdd BLAST31
Coiled coili1003 – 1023Sequence analysisAdd BLAST21
Coiled coili1269 – 1321Sequence analysisAdd BLAST53

Domaini

The CKK domain binds microtubules.PROSITE-ProRule annotation

Sequence similaritiesi

Belongs to the CAMSAP1 family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3Di1.10.418.10, 1 hit
3.10.20.360, 1 hit
InterProiView protein in InterPro
IPR032940 CAMSAP
IPR031372 CAMSAP_CC1
IPR022613 CAMSAP_CH
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR038209 CKK_dom_sf
IPR014797 CKK_domain
IPR011033 PRC_barrel-like_sf
PANTHERiPTHR21595 PTHR21595, 1 hit
PfamiView protein in Pfam
PF17095 CAMSAP_CC1, 1 hit
PF11971 CAMSAP_CH, 1 hit
PF08683 CAMSAP_CKK, 1 hit
SMARTiView protein in SMART
SM01051 CAMSAP_CKK, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
SSF50346 SSF50346, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
PS51508 CKK, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

A0A1S2ZM90-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEAPPDGAAD IVPLDRYDSA RAKIAANLQW ICAKAYGIDN IPEDLRDPFY
60 70 80 90 100
VDQYEQEHIK PPVIKLLLSS ELYCRVCSLI LKGDQVASLQ GHQSVIQALS
110 120 130 140 150
RKGIYVMESD DTPVTDPDLS LTPIKMSSHM AMVDALMMAY TVEMISIEKV
160 170 180 190 200
VASVKRFSTF SASKELPYDL EDAMVFWINK VNLKMREITE KEVKLKQQIL
210 220 230 240 250
ESPAHQKVRY RREHLAARQP PYFPLLEDLM RDGSDGAALL AVIHYYCPEQ
260 270 280 290 300
MKLDDICLKE VTSMADSLYN IRLLREFSNE YLNKCFYLTL EDMLYAPLVL
310 320 330 340 350
KPNVMVFIAE LFWWFENVKP DFVQPRDVQE LKDAKAVSHQ KSSRPPIPIS
360 370 380 390 400
NATKRSFLGS PAAASPADLQ PPAQLPTEGG HRHHLHIEEP EHLSKGTSAF
410 420 430 440 450
SPSHPLLPLR QKQQKTVQGE ENPDQRHRSN SLTRVDGQPR GAAVAWPEKR
460 470 480 490 500
NRPVSQPAPF ALHHAASCDV DPGFGDSISL ARSISKDSLA SNVINLTPQN
510 520 530 540 550
QPHPTALKIN GKSLLNNVDI EDEDEELVAI IRTEVGPHGG DMGLVASARS
560 570 580 590 600
PQRLPDTLES KPDSFFLEPL MPAVLRPAKE KQVITKEDEY GDGKPRSFVS
610 620 630 640 650
KRSSEGHQPL VRKKAPISHI GRDLNRTFTP ISSSELPAGF DPALPEAGLQ
660 670 680 690 700
AAEEAHGGPL PSCGFDLLSQ GQSADGFFLH ITRAEDDAAE GRFHIRSSRS
710 720 730 740 750
PTPLGPEAWT VLRQDSDSDV AEIEEAGHDL MSEDHPALVA RYVGEEESAK
760 770 780 790 800
LQEDMKVKEH EDKDDASGRS SPCLSTVSQI SSVSMASGSV KMTSFAERKL
810 820 830 840 850
QRLNSCETKS STSSSQKTTP DASESCPPPL TTWKQRREQS PTRQNRDHAS
860 870 880 890 900
LLASELVQLH MQLEEKRRAI ETQKKKMEAL SARQRLKLGK AAFLHVVKKG
910 920 930 940 950
KAEIVPQPLK PEHFAREFSQ HNGEDLVDGT VAKMEEFLVK EEGRAELLEA
960 970 980 990 1000
GEVEKESLAL VQQHRLKDPA AVHELEKSRA LSVALLEDGT GEAMDVSECD
1010 1020 1030 1040 1050
LSIEKLNETI STLQQAILKI SQQQEQLLMK SPTVPTPGSK NNSQEQKVKA
1060 1070 1080 1090 1100
SIHFVEPLSP TGMVSHRKPP RLSQGRNSRS GRPAELKVPK DRQQGSSRSK
1110 1120 1130 1140 1150
TPTPNIETLP HLRSFPPSSQ PRTPSDPSCD GIADPGNDTP EKCFFESYRL
1160 1170 1180 1190 1200
HDENNQRTLT LPSCKDANIL SEQTSFKEAP DNSIREAGLS SALPGKESLS
1210 1220 1230 1240 1250
VDEPLRSKAS LIEVDLSDLK APDEDGGLDS HESSADLISE GDQKPGVGFF
1260 1270 1280 1290 1300
FKDEQKAEDE LAKKRAAFLL KQQRKAEEAR MRKQQLEAEV ELKRDEARRK
1310 1320 1330 1340 1350
AEEDRIRKEE EKARRELIKQ EYLRRKQQQI LEEQGLGKPK SKPKKTRPKS
1360 1370 1380 1390 1400
VHREESCSDS GTKCSSTPDN LSRAQSGSSL SLASAATTEP ESIHSGGTPS
1410 1420 1430 1440 1450
QRVESLEALP VLSRNPSRST DRDWETASAA SSLASVAEYT GPKLFKEPSS
1460 1470 1480 1490 1500
KSNKPIIHNA ISHCCLAGKV NEPHKNSILE ELEKCDANHY IILFRDAGCQ
1510 1520 1530 1540 1550
FRALYCYYPD TEEIYKLTGT GPKSITKKMM DKLYKYSSDR KQFNLIPAKT
1560 1570 1580
MSVSVDALTI HNHLWQPKRP AVPKKTQTRK
Length:1,580
Mass (Da):175,861
Last modified:April 12, 2017 - v1
Checksum:iF3B8F33A7B48E9F1
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1S3WA30A0A1S3WA30_ERIEU
calmodulin-regulated spectrin-assoc...
CAMSAP1
1,592Annotation score:
A0A1S3W9C9A0A1S3W9C9_ERIEU
calmodulin-regulated spectrin-assoc...
CAMSAP1
1,581Annotation score:
A0A1S3W998A0A1S3W998_ERIEU
calmodulin-regulated spectrin-assoc...
CAMSAP1
1,591Annotation score:
A0A1S3W958A0A1S3W958_ERIEU
calmodulin-regulated spectrin-assoc...
CAMSAP1
1,591Annotation score:

Sequence databases

RefSeqiXP_007521530.1, XM_007521468.1

Genome annotation databases

GeneIDi103112088

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_007521530.1, XM_007521468.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103112088

Organism-specific databases

CTDi157922

Family and domain databases

Gene3Di1.10.418.10, 1 hit
3.10.20.360, 1 hit
InterProiView protein in InterPro
IPR032940 CAMSAP
IPR031372 CAMSAP_CC1
IPR022613 CAMSAP_CH
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR038209 CKK_dom_sf
IPR014797 CKK_domain
IPR011033 PRC_barrel-like_sf
PANTHERiPTHR21595 PTHR21595, 1 hit
PfamiView protein in Pfam
PF17095 CAMSAP_CC1, 1 hit
PF11971 CAMSAP_CH, 1 hit
PF08683 CAMSAP_CKK, 1 hit
SMARTiView protein in SMART
SM01051 CAMSAP_CKK, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
SSF50346 SSF50346, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
PS51508 CKK, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S2ZM90_ERIEU
AccessioniPrimary (citable) accession number: A0A1S2ZM90
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: May 23, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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