Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

dynein heavy chain 3, axonemal

Gene

DNAH3

Organism
Erinaceus europaeus (Western European hedgehog)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
dynein heavy chain 3, axonemalImported
Gene namesi
Name:DNAH3Imported
OrganismiErinaceus europaeus (Western European hedgehog)Imported
Taxonomic identifieri9365 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaInsectivoraErinaceidaeErinaceinaeErinaceus
Proteomesi
  • UP000079721 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1627 – 1766AAAInterPro annotationAdd BLAST140
Domaini2272 – 2419AAAInterPro annotationAdd BLAST148

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili225 – 252Sequence analysisAdd BLAST28
Coiled coili1018 – 1038Sequence analysisAdd BLAST21
Coiled coili1043 – 1080Sequence analysisAdd BLAST38
Coiled coili3111 – 3176Sequence analysisAdd BLAST66
Coiled coili3427 – 3447Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 5 hits

Sequencei

Sequence statusi: Complete.

A0A1S2ZB49-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAATSTLLLQ NPVQHPELQA CSHDELNAPS PRSSTKASRG QGAAWTRRAS
60 70 80 90 100
PGPGDRAPAG PEKRRTWEEL ESGARTRFAS SVQRAHRLPP TSIKTTPPNR
110 120 130 140 150
GSASSMTTPT GNRSALNVPP SAALLRLHPV SRLHPKVLAK SVSRPRGGFY
160 170 180 190 200
GARSGPQLFV ATRAARGGVQ TRKTELRKSV GSTPQTETSW LSDFPRCEEH
210 220 230 240 250
FTDMISLNVQ PYSKSELGVF WKSSKRETLT AKEELKEEEE SLQKAQQNLC
260 270 280 290 300
AISSRLSLPF SPLQPENSSA FQTQYASLFM SLHIFTIDIF QIQFCHIDPT
310 320 330 340 350
DSIHHMSQCQ AQPELPPLPA SANEQPSELY QTVMLHSIYP PLMQRTSWTL
360 370 380 390 400
AAPFKEQQHH RGPSDSIGNN YSLKAQNLKL KDLQKVYQAV TINVPREKTG
410 420 430 440 450
QEQSLGIYVS NKSSSEPSKK KMKLSYKDKQ DSSGTKLLHK MTSSFIKKVE
460 470 480 490 500
VMTSELPRSR PMSPEEQINV MLQQEKEIES KESKPSSIDL ERYCYYLTNG
510 520 530 540 550
IPKEMIAAEE ADMMVRILKL ISYTLLKSPP LEPLITALTE EKEQDYYRSI
560 570 580 590 600
MKSIVDYILM DPAEKSRLFI KSIPHVFPQR VIRAPVPWHG VYMNAKKWNE
610 620 630 640 650
EHLYTVNPIM LSLKKLWSSE FRNLRFVRTA ELLAGTLPLQ PYEYNSVIQQ
660 670 680 690 700
HCMEARQILL NKWIPTCAHI FTSQKQQWVH FAPKSEYDSS QNIEEYFASV
710 720 730 740 750
GSFMSLQLRE LVIKSLEDLV SFFMIHKGGN DFEEPYKEME FFMPQLIMIK
760 770 780 790 800
LDVSEPNIAF NPTFDNCWQL IYNSFLEIID NSKGIPKVES VLFPELKGYD
810 820 830 840 850
LTLRTVDAEE KLVSDLVNQT FEVFQKNQVG PLKYINVYKK YGDLLNDSAE
860 870 880 890 900
QNVTTFLYEP HEIEDFVMEI NNIKKRKNEI ASMHITVPLA MFCLDALVLN
910 920 930 940 950
YELCERAQSL KDRLIQFQVD VNRDTNTSIC NQYSTIADKV SEIPANTEEL
960 970 980 990 1000
VFLIEFLKKS SDVTVFRLRR QLKDAVERLE FLMDYADLPH QIEDIFENSR
1010 1020 1030 1040 1050
NLLLSKRDQA EMDLIKRCSE FESKLEGYNK ELEGFRKREV MTTEEMKNNV
1060 1070 1080 1090 1100
EKLHELSKNL EQALVEFELI NKEEELLEKE KSTFPLLQTV MTNKVPYEQL
1110 1120 1130 1140 1150
WITTYEFSIK SEEWMNGPLF SLNAEEIAEE IGNMWRTIYK LTKTLTDVPA
1160 1170 1180 1190 1200
PRRLAENVKM KIEKFKQHIP VLTLSCNPGI KERHWQQISE VVGCEIKPTE
1210 1220 1230 1240 1250
TTCLANMLEY GFSKYIDKLE PIGAAASKEY SLEKNLEKMK SDWVNMVFNF
1260 1270 1280 1290 1300
VKYRDTDTNI LCSVDDIQLL LDDHVIKTQT MCGSPFVKPI EAEVRKWEEK
1310 1320 1330 1340 1350
LLRVQEILDA WLKCQVTWLY LEPIFSSEDI IAQMPEEGKK FATVDSYWKS
1360 1370 1380 1390 1400
LMSQALILVE DETEKEKKNC STIHAYSYKF FFLSNDELLE ILSETKDPLR
1410 1420 1430 1440 1450
VQPHLKKCFE GISRLKFTDS LEIVGMISSE KETVPFNQKI NPIQAKGMVE
1460 1470 1480 1490 1500
KWLQQVEQMM LASLREVIRL GMEAYVKIPR NHWVLQWPGQ VVICVSSIFW
1510 1520 1530 1540 1550
TQEVSQALVE KTLPDFLQKS NDQIAQIVQL VRGKLSSGAR LTLGALTVID
1560 1570 1580 1590 1600
VHARDVVAKL SSDNVCDLND FQWISQLRYY WEANDVQVQM ITTEALYGYE
1610 1620 1630 1640 1650
YLGNSPRLVI TPLTDRCYRT LMGALKLNLG GAPEGPAGTG KTETTKDLAK
1660 1670 1680 1690 1700
ALAKQCVVFN CSDGLDYKAM GKFFKGLAQA GAWACFDEFN RIEVEVLSVV
1710 1720 1730 1740 1750
AQQILSIQQA IIRKLKTFIF EGTELALNPT CAVFITMNPG YAGRAELPDN
1760 1770 1780 1790 1800
LKALFRTVAM MVPDYALIGE ISLYSMGFLD SRSLAQKIVA TYRLCSEQLS
1810 1820 1830 1840 1850
SQHHYDYGMR AVKSVLTAAG NLKLKYPEEN ESVLLLRALL DVNLAKFLAQ
1860 1870 1880 1890 1900
DVPLFQGIIS DLFPGVVLPK PDYEVFMGVL NENIKKMKLQ PVPWFIGKII
1910 1920 1930 1940 1950
QIYEMMLVRH GFMIVGDPLG GKTCAYKVLA AALADLHAAQ QMEEFAVDYH
1960 1970 1980 1990 2000
IINPKAITMG QLYGCFDPVS HEWTDGVLAN AFREQASSVS DDRKWIIFDG
2010 2020 2030 2040 2050
PVDAVWIENM NTVLDDNKKL CLMSGEIIQM SPKMSLIFEP ADLEQASPAT
2060 2070 2080 2090 2100
VSRCGMIYME PHQLGWKPLK DSYMDTLPSS LKEDHKELIN DMFMWLIQPC
2110 2120 2130 2140 2150
LEFIRNECKF VVQTSPIHLA FSMMRLYSSL FDEIRTIEGE ESEFSEGPTS
2160 2170 2180 2190 2200
QQIFLWLQGL FLFALVWTVA GTINSDGKKK FDLFFRNLLM GMNDNHPRPK
2210 2220 2230 2240 2250
SVKLTKNNIF PEKGSIYDFY FLKQGGGHWC TWTEYITKEE ENIPPNAKIS
2260 2270 2280 2290 2300
ELIIPTMETA RQSFFLKTYL NHEIPVLFVG PTGTGKSAIT NNFLLHLPKN
2310 2320 2330 2340 2350
TYVPNCINFS ARTSANQTQD IIMSKLDRRR KGVFGPPIGK KAVVFVDDLN
2360 2370 2380 2390 2400
MPAKEVYGAQ PPIELLRQWI DHGYWFDKKD TTKLDIVDVL LVTAMGPPGG
2410 2420 2430 2440 2450
GRNDITGRFT RHLNILSISA FEDEILNKIF SSIADWHFGR GFDVAFLRHG
2460 2470 2480 2490 2500
KILVNATMTI YRAAVENFLP TPSKSHYVFN LRDFSRVIQG VLLCPHTHLQ
2510 2520 2530 2540 2550
DVEKLIRLWI HEIYRVFYDR LTDHEDRQVF FNMMKETTSN CFKQTVEKVL
2560 2570 2580 2590 2600
IHLSPSGKIV DDNIRSLFFG DFFKPESEPK IYDEITDLKQ LTVVMEYYLE
2610 2620 2630 2640 2650
EFNNISKAPM SLVMFKFAIE HISRICRVLK QDKGHLLLVG IGGSGRQSAS
2660 2670 2680 2690 2700
KLSTFMNSYE LYQIEITKNY SGSDWREDLK KIMLQVGVAT KCTVFLFSDN
2710 2720 2730 2740 2750
QIKDESFVED INMLLNTGDV PNIFPADEKA DLVEKMQTAA RTEGEKIEVT
2760 2770 2780 2790 2800
PLSMYNFFID RVKKNLHIVL AMSPIGDSFR NRLRMFPSLI NCCTIDWFQA
2810 2820 2830 2840 2850
WPTDALELVA NKFLEDVELE DSVRKAVISM CKYFQESVKM LSVNYYNTLL
2860 2870 2880 2890 2900
RHNYVTPTSY LELILTFKAL LNSKRQEVDT MRNRYLTGLQ KLDFAASQVA
2910 2920 2930 2940 2950
VMQIELTALQ PQLILTSEET AKMMVKIEAE TREADAKKLL VQADEKEANA
2960 2970 2980 2990 3000
AAAISQGIKD ECEGDLAEAM PALEAALAAL DTLNPADISL VKSMQNPPGP
3010 3020 3030 3040 3050
VKLVMESICV MKGLKPERKP DPSGSGKMIE DYWGVSKKVL GDLKFLESLK
3060 3070 3080 3090 3100
TYDKDNIPSV TMKRIREKFI DHPDFQPSVI KNVSSACEGL CKWVRAMEVY
3110 3120 3130 3140 3150
DRVAKVVAPK RERLKEAEGK LEVQMQKLNL KRAELKLVED RLQALNDDFE
3160 3170 3180 3190 3200
DMNNKKKKLE ENIDLCSQKL VRAEKLISGL GGEKDRWTEA ARQLGIRYTN
3210 3220 3230 3240 3250
LTGDVLLSSG TVAYLGAFTV DYRAECQQQW LAQCKEKVIP GSVDFSLSST
3260 3270 3280 3290 3300
LGDPVKIRAW QIAGLPIDSF SIDNGIIVSN SRRWALMIDP QGQANKWIKN
3310 3320 3330 3340 3350
MEKSNKLSVI KFSDASYVRT LENALQFGTP VLLENVGEEL DAFIEPILLK
3360 3370 3380 3390 3400
STFRQQGVEY MRLGENIIEY AKDFKLYITT RLRNPHYLPE VAVKVCLLNF
3410 3420 3430 3440 3450
MITPLGLQDQ LLGIVAAKEK PELEEKKNKL IVESAKNKKQ LKEIEDKILE
3460 3470 3480 3490 3500
VLSQSEGNIL EDETAIKVLS SSKVLSEEIS EKQTVASITE TQIDQTRMGY
3510 3520 3530 3540 3550
KPVAVHSATI FFCISDLANI EPMYQYSLTW FINLYVQSLA NSEKSDELEH
3560 3570 3580 3590 3600
RISNIIEHFT LSIYNNVCRS LFEKDKLLFS LLLTYGIQKE KKLINEEMWY
3610 3620 3630 3640 3650
FLLTGGISLD NPFPNPASEW LSEKSWGEVV RASSLPRLKG LMEHFIENTD
3660 3670 3680 3690 3700
EWKLIYDSAF PHIEKFPGIW KFLDRLERMV VLRCLRPDKI VPAVRDFIAE
3710 3720 3730 3740 3750
YMGNMFIEPP TFDLQGSYND SNCCAPLIFV LSPGADPMAG LLKFADDVGM
3760 3770 3780 3790 3800
GGAKTQTISL GQGQGPIAAK MINTAIRDGT WVVLQNCHLA TSWMPALEKI
3810 3820 3830 3840 3850
CEEVIVPEST NIRFRLWLTS YPSDKFPVSI LQNGIKMTNE PPKGLRANLL
3860 3870 3880 3890 3900
RSYLNDPISD PVFFQSCTKV VMWQKLLFGL CFFHAIVQER RNFGPLGWNI
3910 3920 3930 3940 3950
PYEFNESDLR ISMRQIQMFL NEYKEVPFEA LTYLTGECNY GGRVTDDKDR
3960 3970 3980 3990 4000
RLLLSLLSTF YCKEIEQDHY YLAPGDIYYV PPHGSYQSYI DYLRNLPITA
4010 4020 4030 4040 4050
HPEVFGLHEN ADITKDNQET NQLFQGVLQT LPRQSGGSGK SPQEAVQELA
4060 4070 4080 4090 4100
QDILSKLPKD FNLEMVMNLY PVVYEESMNT VLRQEVIRFN RLTKVVRVSL
4110 4120 4130 4140 4150
IDLGRAIKGQ VLMSSQLEEV FSSMLLGKVP DLWMTKSYPS LKPLGGYVTD
4160 4170 4180 4190 4200
LLARLAFFQD WINSGPPVVF WISGFYFTQS FLTGVSQNYS RKYTIPIDHI
4210 4220 4230 4240 4250
GFEFEVTSQE MAMESNPDDG AYIKGLFLEG ARWDRKTMKI QESFPKILYD
4260 4270 4280 4290 4300
SLPIIWLKPG ETDTFLHQDI YMCPVYKTSA RRGILSTTGH STNYVLSIEL
4310 4320
PTDRPQKHWI NRGVASLCQL DD
Length:4,322
Mass (Da):493,223
Last modified:April 12, 2017 - v1
Checksum:i113FAD771270A8DD
GO

Sequence databases

RefSeqiXP_007516656.2, XM_007516594.2

Genome annotation databases

GeneIDi103107782

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_007516656.2, XM_007516594.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103107782

Organism-specific databases

CTDi55567

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A1S2ZB49_ERIEU
AccessioniPrimary (citable) accession number: A0A1S2ZB49
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: December 20, 2017
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again