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Protein

Acetaldehyde dehydrogenase

Gene

BMG05_24170

Organism
Mycobacterium malmoense
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD+ and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei131Acyl-thioester intermediateUniRule annotation1
Binding sitei281NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi16 – 19NADUniRule annotation4
Nucleotide bindingi162 – 170NADUniRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotation
Biological processAromatic hydrocarbons catabolismUniRule annotationSAAS annotation
LigandNADUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Acetaldehyde dehydrogenaseUniRule annotationSAAS annotation (EC:1.2.1.10UniRule annotation)
Alternative name(s):
Acetaldehyde dehydrogenase [acetylating]UniRule annotation
Gene namesi
ORF Names:BMG05_24170Imported, BST29_20080Imported
OrganismiMycobacterium malmoenseImported
Taxonomic identifieri1780 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000181742 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 123Semialdhyde_dhInterPro annotationAdd BLAST114

Sequence similaritiesi

Belongs to the acetaldehyde dehydrogenase family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_01657 Ac_ald_DH_ac, 1 hit
InterProiView protein in InterPro
IPR003361 Acetaldehyde_dehydrogenase
IPR015426 Acetylaldehyde_DH_C
IPR036291 NAD(P)-bd_dom_sf
IPR000534 Semialdehyde_DH_NAD-bd
PfamiView protein in Pfam
PF09290 AcetDehyd-dimer, 1 hit
PF01118 Semialdhyde_dh, 1 hit
PIRSFiPIRSF015689 Actaldh_dh_actl, 1 hit
SMARTiView protein in SMART
SM00859 Semialdhyde_dh, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03215 ac_ald_DH_ac, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1S2WEU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSKASVALK VAIVGSGNIS TDLLYKLLRS DWLEPRWMVG IDPQSEGLAR
60 70 80 90 100
ARRLGLETTH EGVDWLLAQP EKPDLVFEAT SAYVHRDAAP KYAAAGIRAI
110 120 130 140 150
DLTPAAVGPA VIPPANLREH LDAPNVNMIT CGGQATIPIV YAVSRVVEVP
160 170 180 190 200
YAEIVASVAS VSAGPGTRAN IDEFTKTTSK GVETIGGAKR GKAIIILNPA
210 220 230 240 250
DPPMIMRDTI FCAIPEDADR EAIAKSIHDV VAEVQTYVPG YRLLNEPQFD
260 270 280 290 300
EPSINSGGQA LVTTFVEVEG AGDYLPPYAG NLDIMTAAAT KVGEEIARKR
310
DATLVAGGTR
Length:310
Mass (Da):32,879
Last modified:April 12, 2017 - v1
Checksum:iCA2E250A94BAA192
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MOWS01000197 Genomic DNA Translation: OIN78418.1
MVHV01000025 Genomic DNA Translation: ORA78924.1
RefSeqiWP_071513133.1, NZ_MVHV01000025.1

Similar proteinsi

Entry informationi

Entry nameiA0A1S2WEU2_MYCMA
AccessioniPrimary (citable) accession number: A0A1S2WEU2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: June 20, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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