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Entry version 10 (16 Jan 2019)
Sequence version 1 (12 Apr 2017)
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Protein

Ochratoxin highly reducing polyketide synthase

Gene

OTApks

Organism
Aspergillus carbonarius (strain ITEM 5010)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of ochratoxin A (OTA), a mycotoxin demonstrated to have nephrotoxic, immunotoxic, genotoxic, neurotoxic, and teratogenic properties (PubMed:24699234). OTA is composed of a chlorinated type I polyketide dihydroisocoumarin moiety linked to L-phenyl-alanine (PubMed:24699234). The highly reducing polyketide synthase (OTApks) catalyzes the formation of the isocoumarin group during the initial stages of biosynthesis, starting from one acetate and 4 malonate units, to originate the characteristic pentaketide skeleton 7-methylmellein (7-MM) of the OTA molecule (PubMed:22983973, PubMed:24699234). 7-MM is then oxidized into 7-carboxymellein (also called ochratoxin beta) (PubMed:27422838). The NRPS encoded by the OTAnrps gene is involved in the linking of phenylalanine to the dihydroisocoumarin ring (PubMed:22983973). The reaction catalyzed by NRPS results in the production of ochratoxin B (OTB), which is the non-chlorinated analog of OTA and which subsequently serves as the substrate of the halogenase (OTAhal) for chlorination activity to form the final molecular structure of OTA, containing a chlorine atom in the C-5 position of the molecule (PubMed:27422838).3 Publications

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pantetheine 4'-phosphateSequence analysisNote: Binds 1 phosphopantetheine covalently.Sequence analysis

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: Mycotoxin biosynthesis

This protein is involved in Mycotoxin biosynthesis.1 Publication
View all proteins of this organism that are known to be involved in Mycotoxin biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei182PROSITE-ProRule annotation1
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei1420S-adenosyl-L-methionine; via amide nitrogenPROSITE-ProRule annotation1
Binding sitei1442S-adenosyl-L-methioninePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Methyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase
LigandNADP, S-adenosyl-L-methionine

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ochratoxin highly reducing polyketide synthase1 Publication (EC:2.3.1.-1 Publication)
Short name:
OTApks1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OTApks1 Publication
ORF Names:ASPCADRAFT_173482
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAspergillus carbonarius (strain ITEM 5010)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri602072 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000188318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Abolishes the porduction of ochratoxin A and its degradation derivative ochratoxin alpha (PubMed:24699234).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004405881 – 2541Ochratoxin highly reducing polyketide synthaseAdd BLAST2541

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2490O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Keywords - PTMi

Phosphopantetheine, Phosphoprotein

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Expression is down-regulated in the presence of fennel, cardamom, chamomile, celery, anise and rosemary essential oils (PubMed:27548221).1 Publication

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A1R3RGK0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2453 – 2530CarrierPROSITE-ProRule annotationAdd BLAST78

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni12 – 434Ketosynthase (KS) domainSequence analysisAdd BLAST423
Regioni571 – 888Malonyl-CoA:ACP transacylase (MAT) domainSequence analysisAdd BLAST318
Regioni957 – 1250Dehydrogenase (DH) domainSequence analysisAdd BLAST294
Regioni1433 – 1605Methyltransferase (CMeT) domainSequence analysisAdd BLAST173
Regioni1857 – 1919Enoyl reductase (ER) (ER) domainSequence analysisAdd BLAST63
Regioni2165 – 2344Ketoreductase (KR) domainSequence analysisAdd BLAST180

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
19161at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 1 hit
3.40.366.10, 1 hit
3.40.47.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001227 Ac_transferase_dom_sf
IPR036736 ACP-like_sf
IPR014043 Acyl_transferase
IPR016035 Acyl_Trfase/lysoPLipase
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR032821 KAsynt_C_assoc
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR016036 Malonyl_transacylase_ACP-bd
IPR013217 Methyltransf_12
IPR036291 NAD(P)-bd_dom_sf
IPR020801 PKS_acyl_transferase
IPR020841 PKS_Beta-ketoAc_synthase_dom
IPR020807 PKS_dehydratase
IPR020843 PKS_ER
IPR013968 PKS_KR
IPR020806 PKS_PP-bd
IPR009081 PP-bd_ACP
IPR029063 SAM-dependent_MTases
IPR016039 Thiolase-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00698 Acyl_transf_1, 1 hit
PF08240 ADH_N, 1 hit
PF16197 KAsynt_C_assoc, 1 hit
PF00109 ketoacyl-synt, 1 hit
PF02801 Ketoacyl-synt_C, 1 hit
PF08659 KR, 1 hit
PF08242 Methyltransf_12, 1 hit
PF00550 PP-binding, 1 hit
PF14765 PS-DH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00827 PKS_AT, 1 hit
SM00826 PKS_DH, 1 hit
SM00829 PKS_ER, 1 hit
SM00825 PKS_KS, 1 hit
SM00823 PKS_PP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336 SSF47336, 1 hit
SSF50129 SSF50129, 1 hit
SSF51735 SSF51735, 2 hits
SSF52151 SSF52151, 1 hit
SSF53335 SSF53335, 1 hit
SSF53901 SSF53901, 1 hit
SSF55048 SSF55048, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 1 hit
PS50075 CARRIER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1R3RGK0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTFTSHPQSE PLAIIGLACK YANDINSPLD LYQQVMAARS MHGPMPPSRM
60 70 80 90 100
DAAFYYHPSS EATGTTYAKG GYFLQSDLNA FDSPFFQLSE IDVLAMDPQQ
110 120 130 140 150
KMLLENVYHA LENAGIPLKD AVSSSTSVFV GCSNNDHLAL ANADLLLALK
160 170 180 190 200
GKGTGTSPSI LANRISWFYD FQGTSQTIDT ACSSSLVAFH QGCMDVRAGK
210 220 230 240 250
STMSIISGVN LMEHPAPTMY LSSLGVLSPD GRSMSFDARA NGYGRGEGLG
260 270 280 290 300
TVIIKPLTAA LRDGNRIRAI VRSTGSNQDG RTPGITVPSP TAQERLIREV
310 320 330 340 350
YKAADLDPSR TGYVEAHGTG TPVGDPLEVQ AISAALGMSR DSPLYVGSVK
360 370 380 390 400
SVVGHLEGGA GMAGLISATM AVESKTIPPV AGLQTLNPRI PQRPDLKFAK
410 420 430 440 450
EATPWPREDV RRASINSFGF GGTNAHVVLE DVEGFFSDLF GQQLPGALQL
460 470 480 490 500
SEVTSKALVP SAMKSAVNGI PADQPPKESS VNRLFVISAF DEAGIQRNAA
510 520 530 540 550
SLASHLESMR AITGSDGEER LLNDLCHTLN EKRTRFDWRS YHVADSIDSL
560 570 580 590 600
RNSLQNPRPI RQSPAEKVVR FIFTGQGANW AGMAYDLLVY PLFRRRIQEA
610 620 630 640 650
AIFLKELGSD WDLYERIASQ SGELDEPTFA QSSCVAVQVA LVDLLASWNV
660 670 680 690 700
TPQTVVGHSS GEIAAAYCAG QISRQAAWKV AFCRGQVCAR RTDGQGRMLA
710 720 730 740 750
AAMPVTQLEQ LVARVNKGQS TAVKVGCYNS PKNLTLTGRA EDILRAKLEL
760 770 780 790 800
DDVGALNRLL PVKVAYHSDY MRDAAPEYLD LLGDLDFGDS IHADAGIKMV
810 820 830 840 850
SSVTGRAVSA GEAQQPSYWV DNLVSPVRFS TALLASMDDP SATGAREDAL
860 870 880 890 900
IEIGPHSTLR TAIKETFADV REFQSIQYGS LLKRYETDGS TILRTFGMLV
910 920 930 940 950
CSGHKISLAA INDRRVGAKK TPRLLTGLPS YAFDHSRSMR GTSRRIEQAK
960 970 980 990 1000
FPAYKRHELL GVPVEDTNPV EQRWRNILRP DDLPWLRMNR MNGQIHFPGV
1010 1020 1030 1040 1050
AYLLMATEAA IQRVGNTVAI SGVRLGNVSM LAPLPIPDSA AGVEIQFSIY
1060 1070 1080 1090 1100
PMKIHANSGT DWSTFRIVSY DSAEKTWTEH CVGSVRVETG PHESHEPHPG
1110 1120 1130 1140 1150
NATREECTES VDIAQMYSRF TTAGMDFGEY LRNIQEMKLS PDHQACTATI
1160 1170 1180 1190 1200
TAPDIPCQAH DHYSLHPCTF ESILHALLHL CKSSQGPMVT TYIEEVLVLS
1210 1220 1230 1240 1250
PQDTGVCGFE ACAQTQRASA TTWRSDVTIT ANTGRQQIRV TGLDLVQLPP
1260 1270 1280 1290 1300
SEDASDAESF YVVKWKPDVK LLTSVDALRD SASMYVAQHL PTLDEHEGFQ
1310 1320 1330 1340 1350
LASGIFLLDT MDYVTRTGLP ALPQHHQAFM QWMEKECRSI ADGTVPLLDT
1360 1370 1380 1390 1400
ALFEGIRASP DRRRELLARV AQLSARGELL VRVGTQMVPI LEQKIDCLEV
1410 1420 1430 1440 1450
MFGPDNLMDR TYEEGLPGQI APSVAGYLHC LAHAQTGIKV LEVGAGTGSA
1460 1470 1480 1490 1500
TKVILDSLKP TERQDGGGLV SSVSTYHFTD ISAAFFEKAR ARFPDWADIL
1510 1520 1530 1540 1550
RPKVLNIELD PADQGFEMGS YDLVIATHVL HATADLSVSL KNIRGLLKEG
1560 1570 1580 1590 1600
GDLIVIENIQ PDLMCSPLAF GLLPGWWRSV EPYRKTNPLI TKDQWDQELR
1610 1620 1630 1640 1650
NAGLQSRLLI DDTDEGVNEM TAFVASRVRE PPATQHVCSI IYSSRYGGQY
1660 1670 1680 1690 1700
ELASQVARDL PPSCTASLVD LADISPEHTS TIGIVLVGYQ GLDLSELSAH
1710 1720 1730 1740 1750
EYDRVNFLLT AFHRLLWVTC DEDEVPKSAM ASGLVRTARW ERDHDGVNFI
1760 1770 1780 1790 1800
LLGISHRVPS ASAAVSQMIR VCDHAFFSHE LVPRNAEFRL EGSVLLTNRL
1810 1820 1830 1840 1850
FPATGINECI ASSSRPRSKQ VALEAVQHPV KLTSIGPHQP NGFHFVEDPQ
1860 1870 1880 1890 1900
VDEPLLPDEV KIQIRAVGLD ESDVEEMNRL IPGESAGSQG TGVVVEVGPA
1910 1920 1930 1940 1950
VHDIHVGDRV MALRTGHSGS LQTVLRTHSS AVTQVPEGLS LADAAAVPLP
1960 1970 1980 1990 2000
FTTAYHGLVN VARLEPQDTI LIHNAGGATG QAAVQFACML GATVYATVES
2010 2020 2030 2040 2050
DAQRQALLDY GVDRSRLLDG PSFAQQLARR GAKGSVDVLF NLSRESLEDR
2060 2070 2080 2090 2100
DLACLSQFGR LVGVHGQGSL PAGPTNRSYA TVSIRELVQV RPKALHGTLR
2110 2120 2130 2140 2150
TISDLLTSRA IRPITPVRAG YSELQTVLSQ IRQGNAGPWV LEPRANDTIP
2160 2170 2180 2190 2200
VAMKPLGDYQ FDPCASYLLI GGFGGIGRSV VRWMLTRGAK NFIFLSRSGA
2210 2220 2230 2240 2250
SSVPAKQLCA DLLDAGCGVS DTVCDVTDAT AVENALQQCG KSMPPIRGCL
2260 2270 2280 2290 2300
QCSMVLEDSM LSNMSHAQFL NAITPKVQGT IHVASALSSV KSNLDFFVLL
2310 2320 2330 2340 2350
SSSAGIIGNR GQANYSAANA FLDAFAAHLV SRGYPATSIS LGSVLSVGWV
2360 2370 2380 2390 2400
AENQDRLPIA LSYGAISEDL LLAILEYHMD PSWGAAQSPG TCHTVAGVRS
2410 2420 2430 2440 2450
ARDFQRQSIP LPGFMAYPLF SPLRAIAGAS QTAEEVAEAP IAQGLRGATS
2460 2470 2480 2490 2500
MEDAVELVTR AIVYKLARIM ALSAKEIDAQ RSLASYGVDS LVTVDLKAWF
2510 2520 2530 2540
QREVGATVAS GDLLGDSTIV QLAQQAAGGS RLVSVAMKGT E
Length:2,541
Mass (Da):274,798
Last modified:April 12, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF2ACF09BA03616CF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KV907504 Genomic DNA Translation: OOF93599.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
OOF93599; OOF93599; ASPCADRAFT_173482

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KV907504 Genomic DNA Translation: OOF93599.1

3D structure databases

SMRiA0A1R3RGK0
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiOOF93599; OOF93599; ASPCADRAFT_173482

Phylogenomic databases

OrthoDBi19161at2759

Family and domain databases

Gene3Di1.10.1200.10, 1 hit
3.40.366.10, 1 hit
3.40.47.10, 1 hit
InterProiView protein in InterPro
IPR001227 Ac_transferase_dom_sf
IPR036736 ACP-like_sf
IPR014043 Acyl_transferase
IPR016035 Acyl_Trfase/lysoPLipase
IPR013154 ADH_N
IPR011032 GroES-like_sf
IPR032821 KAsynt_C_assoc
IPR018201 Ketoacyl_synth_AS
IPR014031 Ketoacyl_synth_C
IPR014030 Ketoacyl_synth_N
IPR016036 Malonyl_transacylase_ACP-bd
IPR013217 Methyltransf_12
IPR036291 NAD(P)-bd_dom_sf
IPR020801 PKS_acyl_transferase
IPR020841 PKS_Beta-ketoAc_synthase_dom
IPR020807 PKS_dehydratase
IPR020843 PKS_ER
IPR013968 PKS_KR
IPR020806 PKS_PP-bd
IPR009081 PP-bd_ACP
IPR029063 SAM-dependent_MTases
IPR016039 Thiolase-like
PfamiView protein in Pfam
PF00698 Acyl_transf_1, 1 hit
PF08240 ADH_N, 1 hit
PF16197 KAsynt_C_assoc, 1 hit
PF00109 ketoacyl-synt, 1 hit
PF02801 Ketoacyl-synt_C, 1 hit
PF08659 KR, 1 hit
PF08242 Methyltransf_12, 1 hit
PF00550 PP-binding, 1 hit
PF14765 PS-DH, 1 hit
SMARTiView protein in SMART
SM00827 PKS_AT, 1 hit
SM00826 PKS_DH, 1 hit
SM00829 PKS_ER, 1 hit
SM00825 PKS_KS, 1 hit
SM00823 PKS_PP, 1 hit
SUPFAMiSSF47336 SSF47336, 1 hit
SSF50129 SSF50129, 1 hit
SSF51735 SSF51735, 2 hits
SSF52151 SSF52151, 1 hit
SSF53335 SSF53335, 1 hit
SSF53901 SSF53901, 1 hit
SSF55048 SSF55048, 1 hit
PROSITEiView protein in PROSITE
PS00606 B_KETOACYL_SYNTHASE, 1 hit
PS50075 CARRIER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOTA1_ASPC5
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1R3RGK0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2017
Last sequence update: April 12, 2017
Last modified: January 16, 2019
This is version 10 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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