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Protein
Submitted name:

Beta-hexosaminidase

Gene

BHV59_00330

Organism
Bifidobacterium sp. 56_9_plus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Beta-hexosaminidaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:BHV59_00330Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBifidobacterium sp. 56_9_plusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1897062 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1580 – 1601HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 151F5/8 type CInterPro annotationAdd BLAST151
Domaini152 – 310F5/8 type CInterPro annotationAdd BLAST159

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.260, 3 hits
3.30.379.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025705 Beta_hexosaminidase_sua/sub
IPR013320 ConA-like_dom_sf
IPR000421 FA58C
IPR008979 Galactose-bd-like_sf
IPR015883 Glyco_hydro_20_cat
IPR017853 Glycoside_hydrolase_SF
IPR029018 Hex-like_dom2
IPR015882 HEX_bac_N
IPR022038 Ig-like_bact

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07523 Big_3, 2 hits
PF00754 F5_F8_type_C, 2 hits
PF00728 Glyco_hydro_20, 1 hit
PF02838 Glyco_hydro_20b, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00738 GLHYDRLASE20

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785 SSF49785, 3 hits
SSF49899 SSF49899, 1 hit
SSF51445 SSF51445, 1 hit
SSF55545 SSF55545, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50022 FA58C_3, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A1Q6EU80-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLTGVTAAQ ASDDNLALNQ TVTASSYEVA TTAPEKAVDG DLGTRWGTAQ
60 70 80 90 100
NKAANEWIEV GLGGTKTVKQ INIDFERKDA DQNITSFKVE LKQGDTYTKV
110 120 130 140 150
YQKDTRAKQQ EIILLDQAQQ ASAVKVTVLS ADGGTMNWVN VGINEISVYS
160 170 180 190 200
APKETVLDTA DTNHMLGATM TASSNETATL TPDKAIDQNR TGRNNRWASG
210 220 230 240 250
YETPSNIWLK AEFPRLTAVK DIRIYFFERD VNPKPTNVQS FDLSYTDSEG
260 270 280 290 300
TEHTLKSGYA MTASGAGYVA DVVIQLDQAV NARSLKLSNF AIKSSEYNNV
310 320 330 340 350
SVAEWEAYSN DQAEPGATLD SVVSDLESNH LTIETDTDTL ALPTVPDGYT
360 370 380 390 400
VKFNGADYEQ LIAADGTVNH PLVDKTVQVA YVVTDTATGN TKTTSDIPYV
410 420 430 440 450
VKGTNQQQEG NNAKPTIIPE IAEWHSTSAA KLAASAVTKV VYDDDSLKAV
460 470 480 490 500
VDEFVADYKD FTGIKLTAKK GAAEAGAFNF VKTDSTAAIA QLGDEGYTMD
510 520 530 540 550
IRADRVVAKS SSVTGNMYAM QTILQMTKQD ANGFVIGSMR DYPRFTTRGL
560 570 580 590 600
LLDVARKPVS LEMMREITRT MRYYKMNDFQ AHLSDNYIFL ENYGKGDNED
610 620 630 640 650
EAFKAYDAFR LESSLTNDKG ESPTAEDYSI SKKTFKQFIQ DERALGMNVV
660 670 680 690 700
PEIDVPAHAN SFTKIWPELM VKGRVSPINS NRPLIDHLDV SKPETIAKIK
710 720 730 740 750
EIFDDYTKGD DPTFDSDTTV HIGADEFLYN YTAYRKFINE IVPYIKDTNT
760 770 780 790 800
VRMWGGLTWI NDHKTEITKD AIENVEMNLW SKDWADGLQM YNMGYKLINT
810 820 830 840 850
IDDYGYMVPN GSYGRANAYG DLLNISRVFD SFEPNKVRSS GGYQAVPSGD
860 870 880 890 900
DQMLGAAFAI WSDNIDKSAS GLTESDLYWR FFDAMPFYAE KTWAATGKEK
910 920 930 940 950
GTAAKLTALA AKQGTGPRTN PYYQATSKNS VYESYDFNDG LADASGNGRD
960 970 980 990 1000
LTIGDGSKAA VKDQSLKLAG GSSYATSKLD KLGNGNELTF DVTLQQAAKP
1010 1020 1030 1040 1050
GDILFEADAP YGTHDIRVME NGKLGFTREL YNYYFDYELP VGKTVTVTIK
1060 1070 1080 1090 1100
VDQQTTKLYV DGEFVSDATG KYIDKGIEKK TGITAATFAL PLQRIGSKTS
1110 1120 1130 1140 1150
AINGVIDNVI VKKSEAETDQ YNKSCWTGTT NSETQYNDTE GLLRYAFDNN
1160 1170 1180 1190 1200
PSTIWHSNWK GATDKLTGSN SFYAEIDMCQ KYTINQFSFT PRTSQDSGQV
1210 1220 1230 1240 1250
TKADLYVKAN ANDEWKQVAT DQVFEASRAK KTFMFDEQEV RYVKFVAKSS
1260 1270 1280 1290 1300
NDGWVAVSEF GVANKPSSTV RVFVAADPAE GGTVSVAAEG ETGTDTAVDV
1310 1320 1330 1340 1350
ASGASVTAKA VAADGYRFSG WFTTASETAV STDATYTFAA DGNTALTAKF
1360 1370 1380 1390 1400
TKDSTPDPGP KPTISSIAVT KPTVTDYKVG DTFDATGLAV TATMSDGSTK
1410 1420 1430 1440 1450
TLTAGEYTLS ATQDGAAVAL DKAFAKAGKV TVTVTANGKT ATFDVTVTAK
1460 1470 1480 1490 1500
DPDPEPATLK SIKVTSKPDK TTYTVDETFA KTGLAVTGTW SDGKTALLKD
1510 1520 1530 1540 1550
GEYKLSAVDA DGKTVDLTKP FTAAGDVTVT VTSGKLTDSF TITVKAKTVT
1560 1570 1580 1590 1600
PAPGDNKPGE NKPGADKPKP NTPDEVAKTG ASVTAVVFSA LLLLSAGYLL

VRKRRI
Length:1,606
Mass (Da):174,230
Last modified:April 12, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA6AEA31310DC16A9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
MNQA01000001 Genomic DNA Translation: OKY90178.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MNQA01000001 Genomic DNA Translation: OKY90178.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.120.260, 3 hits
3.30.379.10, 1 hit
InterProiView protein in InterPro
IPR025705 Beta_hexosaminidase_sua/sub
IPR013320 ConA-like_dom_sf
IPR000421 FA58C
IPR008979 Galactose-bd-like_sf
IPR015883 Glyco_hydro_20_cat
IPR017853 Glycoside_hydrolase_SF
IPR029018 Hex-like_dom2
IPR015882 HEX_bac_N
IPR022038 Ig-like_bact
PfamiView protein in Pfam
PF07523 Big_3, 2 hits
PF00754 F5_F8_type_C, 2 hits
PF00728 Glyco_hydro_20, 1 hit
PF02838 Glyco_hydro_20b, 1 hit
PRINTSiPR00738 GLHYDRLASE20
SUPFAMiSSF49785 SSF49785, 3 hits
SSF49899 SSF49899, 1 hit
SSF51445 SSF51445, 1 hit
SSF55545 SSF55545, 1 hit
PROSITEiView protein in PROSITE
PS50022 FA58C_3, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A1Q6EU80_9BIFI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A1Q6EU80
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2017
Last sequence update: April 12, 2017
Last modified: December 5, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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