UniProtKB - A0A1P8B590 (IQD19_ARATH)
Protein IQ-DOMAIN 19
IQD19
Functioni
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).
Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity).
Acts as a positive regulator of trichome branch initiation (PubMed:10572032).
May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
By similarity1 PublicationMiscellaneous
GO - Molecular functioni
- calmodulin binding Source: UniProtKB-KW
GO - Biological processi
- trichome branching Source: UniProtKB
Keywordsi
Molecular function | Calmodulin-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Protein IQ-DOMAIN 191 PublicationShort name: AtIQD191 Publication Alternative name(s): Protein FURCA 31 Publication |
Gene namesi | Name:IQD191 Publication Synonyms:FRC31 Publication Ordered Locus Names:At4g14750Imported ORF Names:dl3415wImported, FCAALL.303Imported |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G14750 |
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication
Cytoskeleton
- cytoskeleton 1 Publication
Cytoskeleton
- cytoskeleton Source: UniProtKB-SubCell
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Cell membrane, Cytoplasm, Cytoskeleton, MembranePathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000453125 | 1 – 446 | Protein IQ-DOMAIN 19Add BLAST | 446 |
Proteomic databases
ProteomicsDBi | 214432 |
Interactioni
Subunit structurei
Binds to multiple calmodulin (CaM) in the presence of Ca2+ and CaM-like proteins.
By similarityGO - Molecular functioni
- calmodulin binding Source: UniProtKB-KW
Protein-protein interaction databases
STRINGi | 3702.AT4G14750.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 163 – 191 | IQ 1PROSITE-ProRule annotationAdd BLAST | 29 | |
Domaini | 192 – 214 | IQ 2PROSITE-ProRule annotationAdd BLAST | 23 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 93 – 140 | DisorderedSequence analysisAdd BLAST | 48 | |
Regioni | 214 – 231 | Calmodulin-binding1 PublicationAdd BLAST | 18 | |
Regioni | 332 – 398 | DisorderedSequence analysisAdd BLAST | 67 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 119 – 140 | Pro residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 375 – 391 | Polar residuesSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | ENOG502QS5R, Eukaryota |
Family and domain databases
InterProi | View protein in InterPro IPR025064, DUF4005 IPR000048, IQ_motif_EF-hand-BS |
Pfami | View protein in Pfam PF13178, DUF4005, 1 hit PF00612, IQ, 2 hits |
SMARTi | View protein in SMART SM00015, IQ, 2 hits |
PROSITEi | View protein in PROSITE PS50096, IQ, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
10 20 30 40 50
MVLGCPKREA VKEFGVQCLK QENVCPIITS RNQTHTHTHI TISSSLTLHN
60 70 80 90 100
GGLSLQKIIM GKTSKWFRSL LTGKKERTKE HIIQSECVFT SSIPGTPKEK
110 120 130 140 150
RRWSFRRSSA TGPPPPACAI TLKDSPPPPP PPPPPPPLQQ PFVVEIVDNE
160 170 180 190 200
DEQIKNVSAE EIEEFAAIKI QACYRSHLAR KALRALKGLV KLQALVRGHL
210 220 230 240 250
VRKQATATLR CMQALITLQA KAREQRIRMI GGDSTNPRTS IHKTRINNFY
260 270 280 290 300
HENEENIKIV EMDIQSKMYS PAPSALTEMS PRAYSSHFED CNSFNTAQSS
310 320 330 340 350
PQCFSRFKEY YNGDTLSSYD YPLFPNYMAN TQSSKAKARS QSAPKQRPPE
360 370 380 390 400
IYEKQMSGRR RSSMEAPRNN GVPRAVRMQR SSSQLGSNTA KESQQHHHHQ
410 420 430 440
YYPWMAIKLD RSNISLMESE CGSTSTVMTN TNYGRHVDVQ GNNNMY
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF4JIF3 | F4JIF3_ARATH | IQ-domain 19 | IQD19 IQ-domain 19, At4g14750, Dl3415W, FCAALL.303 | 387 | Annotation score: | ||
A0A1P8B5B0 | A0A1P8B5B0_ARATH | IQ-domain 19 | IQD19 IQ-domain 19, At4g14750, Dl3415W, FCAALL.303 | 460 | Annotation score: |
Sequence cautioni
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z97337 Genomic DNA Translation: CAB10254.1 Sequence problems. AL161539 Genomic DNA Translation: CAB78517.1 Sequence problems. CP002687 Genomic DNA Translation: ANM66770.1 AY080719 mRNA Translation: AAL86322.1 |
PIRi | D71410 |
RefSeqi | NP_001328646.1, NM_001340965.1 |
Genome annotation databases
EnsemblPlantsi | AT4G14750.1; AT4G14750.1; AT4G14750 AT4G14750.2; AT4G14750.2; AT4G14750 |
GeneIDi | 827130 |
Gramenei | AT4G14750.1; AT4G14750.1; AT4G14750 AT4G14750.2; AT4G14750.2; AT4G14750 |
KEGGi | ath:AT4G14750 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z97337 Genomic DNA Translation: CAB10254.1 Sequence problems. AL161539 Genomic DNA Translation: CAB78517.1 Sequence problems. CP002687 Genomic DNA Translation: ANM66770.1 AY080719 mRNA Translation: AAL86322.1 |
PIRi | D71410 |
RefSeqi | NP_001328646.1, NM_001340965.1 |
3D structure databases
SMRi | A0A1P8B590 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT4G14750.1 |
Proteomic databases
ProteomicsDBi | 214432 |
Genome annotation databases
EnsemblPlantsi | AT4G14750.1; AT4G14750.1; AT4G14750 AT4G14750.2; AT4G14750.2; AT4G14750 |
GeneIDi | 827130 |
Gramenei | AT4G14750.1; AT4G14750.1; AT4G14750 AT4G14750.2; AT4G14750.2; AT4G14750 |
KEGGi | ath:AT4G14750 |
Organism-specific databases
Araporti | AT4G14750 |
Phylogenomic databases
eggNOGi | ENOG502QS5R, Eukaryota |
Gene expression databases
ExpressionAtlasi | A0A1P8B590, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR025064, DUF4005 IPR000048, IQ_motif_EF-hand-BS |
Pfami | View protein in Pfam PF13178, DUF4005, 1 hit PF00612, IQ, 2 hits |
SMARTi | View protein in SMART SM00015, IQ, 2 hits |
PROSITEi | View protein in PROSITE PS50096, IQ, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | IQD19_ARATH | |
Accessioni | A0A1P8B590Primary (citable) accession number: A0A1P8B590 Secondary accession number(s): O23331, Q8RXR4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 2, 2021 |
Last sequence update: | April 12, 2017 | |
Last modified: | September 29, 2021 | |
This is version 22 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families