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Protein

Sodium/potassium-transporting ATPase subunit alpha

Gene

XELAEV_18036444mg

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processIon transport, Potassium transportUniRule annotation, Transport
LigandATP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotation, Nucleotide-binding, Potassium

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/potassium-transporting ATPase subunit alphaUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
ORF Names:XELAEV_18036444mgImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus
Proteomesi
  • UP000186698 Componenti: Chromosome 7l

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei103 – 124HelicalUniRule annotationAdd BLAST22
Transmembranei136 – 156HelicalUniRule annotationAdd BLAST21
Transmembranei298 – 322HelicalUniRule annotationAdd BLAST25
Transmembranei328 – 351HelicalUniRule annotationAdd BLAST24
Transmembranei797 – 817HelicalUniRule annotationAdd BLAST21
Transmembranei856 – 877HelicalUniRule annotationAdd BLAST22
Transmembranei961 – 981HelicalUniRule annotationAdd BLAST21
Transmembranei993 – 1009HelicalUniRule annotationAdd BLAST17

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 123Cation_ATPase_NInterPro annotationAdd BLAST75

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili22 – 68Sequence analysisAdd BLAST47

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. [View classification]UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Family and domain databases

CDDicd02608 P-type_ATPase_Na-K_like, 1 hit
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR006068 ATPase_P-typ_cation-transptr_C
IPR004014 ATPase_P-typ_cation-transptr_N
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR005775 P-type_ATPase_IIC
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00689 Cation_ATPase_C, 1 hit
PF00690 Cation_ATPase_N, 1 hit
SMARTiView protein in SMART
SM00831 Cation_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 3 hits
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01106 ATPase-IIC_X-K, 1 hit
TIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A1L8FPE5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKKEQHDMF SVEMERDGDE GMDVKIKKKN KANKKKEKLE SMKKEMDIND
60 70 80 90 100
HEITIEELEQ KYNTSVSKGL KSTFAAEIIL RDGPNELKPP KGTPEYIKFA
110 120 130 140 150
RQLAGGLQCL MWVAAVICLI AFGIEESQGD LTSADNLYLA ITLIAVVVVT
160 170 180 190 200
GCFGYYQEFK STNIIASFKN LVPQQATVVR DGEKFLINAN QLVVGDLVEI
210 220 230 240 250
KGGDRVPADI RIITSQGCKV DNSSLTGESE PQTRSPEYTH ESPLETRNIA
260 270 280 290 300
FFSTMCLEGT AIGVIINTGD RTIIGRIATL ASGVGNEKTP IAIEIEHFVD
310 320 330 340 350
IIAGLAIFFG ATFFVVAMVI GYPFLRAMVF FMAIVVAYVP EGLLATVTVC
360 370 380 390 400
LSLTAKRLAR KNCVVKNLEA VETLGSTSVI CSDKTGTLTQ NRMTVSHLWF
410 420 430 440 450
DNHIHSADTT EDQSGQSFDQ TSDTWRALSK VVSLCNRAFF KSGQDGIPVP
460 470 480 490 500
KRIVIGDASE TALVKFSEIT VGNVMEYRER FKKVTEVPFN STNKFQLSIH
510 520 530 540 550
ELQDPLDLRY LMVMKGAPER ILERCSTIMI KGQELPLDEQ WKEAFQTAYM
560 570 580 590 600
DLGGLGERVL GFCHLYLNEK EYPRGFNFDT EEMNFPTSGL CFAGLISMID
610 620 630 640 650
PPRATVPDAV MKCRTAGIRV IMVTGDHPIT AKAIAASVGI ISEGSETVED
660 670 680 690 700
IAARLRIPVE QVNKRDARAC VINGGQLKEM SSEELVEALK LHPEMVFART
710 720 730 740 750
SPQQKLIIVE SCQKLGAIVA VTGDGVNDSP ALKKADIGVA MGIAGSDAAK
760 770 780 790 800
NAADMILLDD NFASIVTGVE QGRLIFDNLK KSIAYTLTKN IPELAPYLIY
810 820 830 840 850
ITASVPLPLG CITILFIELC TDIFPSVSLA YERAESDIMH LKPRNPRRDR
860 870 880 890 900
LVNEALAVYS YFQIGIIQSF AGFVDYFTVM AQEGWFPAYV LGLRSHWENQ
910 920 930 940 950
HLQDLQDSYG QEWTFSQRLY QQYNCYTVFF ISIEICQISD VLIRKTRRLS
960 970 980 990 1000
VFQQGFFRNK VLVIAIVFQL CLGNFLCYCP GMPNVFNFMP IRFQWWLVPL
1010 1020 1030
PFGILIFVYD EIRKLGVRRH PGSWFDKEMY Y
Length:1,031
Mass (Da):115,114
Last modified:March 15, 2017 - v1
Checksum:iE209E81196A31D0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM004478 Genomic DNA Translation: OCT73467.1

Similar proteinsi

Entry informationi

Entry nameiA0A1L8FPE5_XENLA
AccessioniPrimary (citable) accession number: A0A1L8FPE5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 15, 2017
Last sequence update: March 15, 2017
Last modified: February 28, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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